Protein Alignment Cyp6a18 and Cyp12b2

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_611370.2
• Gene: Cyp12b2 / 37163
• FlyBaseID: FBgn0034387
• Length: 535
• Species: Drosophila melanogaster
• Alignment Length: 415
• Identity: 106/415 - (25%)
• Similarity: 173/415 - (41%)
• Gaps: 72/415 - (17%)

  Fly   126 GPQWRLLRSKLSSTFTSGKMKFM-----YPTVVSVAEEFMAVMH-EKVSENSIL--DVRDLVARF 182
            |.:|..:|:|::...    ||..     .|.:..:::||:..:. ::..|...|  |..:.:..:
  Fly   156 GQEWADIRNKVNPVL----MKVQNVRQNLPQLDQISKEFIDKLETQRNPETHTLTTDFHNQLKMW 216

  Fly   183 TVDVIGTCAFGIKCNSLRDE---KAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTA 244
            ..:.|...|...:...|.|.   .|:.|         ::|       ||.:.|.:.:..:   ..
  Fly   217 AFESISFVALNTRMGLLSDNPDPNADRL---------AKH-------MRDFFNYSFQFDV---QP 262

  Fly   245 QIQEFYQR--IVKETVTLREKENIKRNDFMDMLIGL-KNQKNMT-------LE-NGEVVKGLTMD 298
            .|..||:.  ..|...|.....:|..|.....:.|. ||....|       || |.:|...:.||
  Fly   263 SIWTFYKTAGFKKFLKTYDNITDITSNYIETAMRGFGKNDDGKTKCVLEQLLEHNKKVAVTMVMD 327

  Fly   299 EIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLD 363
                    ..:||.||:||.....||.||:|||.|:|:|.||.::|.......|.:..|::.||.
  Fly   328 --------MLMAGIDTTSSACLTILYHLARNPSKQEKLRRELLRILPTTKDSLTDQNTKNMPYLR 384

  Fly   364 QVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERF 428
            ..|.|.||..:|.|...|:..|..|:.|   :.:..|..|::....:.:|...:.:.:||.|||:
  Fly   385 ACIKEGLRITSITPGNFRITPKDLVLSG---YQVPRGTGVLMGVLELSNDDKYFAQSSEFIPERW 446

  Fly   429 -----------SPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPD 482
                       .|....:.|.| :||||.|||.|||.|..:::....|..|::::..|....||
  Fly   447 LKSDLAPDIQACPAARTRNPFV-YLPFGFGPRTCIGKRIAELEIETLLVRLLRSYKVSWLPETP- 509

  Fly   483 PLTFDPHSAILLGIKGGIQLKVEAI 507
               .:..|.|:|...|.|:.|:|.:
  Fly   510 ---IEYESTIILSPCGDIRFKLEPV 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	103/406 (25%)
Cyp12b2	NP_611370.2	CYP24A1-like	87..525	CDD:410677	103/407 (25%)