Protein Alignment Cyp6a18 and Cyp317a1

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001286435.1
• Gene: Cyp317a1 / 36667
• FlyBaseID: FBgn0033982
• Length: 518
• Species: Drosophila melanogaster
• Alignment Length: 503
• Identity: 160/503 - (31%)
• Similarity: 274/503 - (54%)
• Gaps: 22/503 - (4%)

  Fly    10 VAVALLAIVTYILHRKLTYFKRRGIPYDKPHPL----RGNMEGYKKTRTVH-EIHQEYYNKYRNS 69
            :.:.||.::......:..|::...||:::|..|    |..|.....|..:. |.:...|.|::.|
  Fly    11 LVLGLLVLLIIAARYQRDYWRYLDIPHERPKKLWPIIRQIMTQTLSTEAMKAEHYSAIYKKFKGS 75

  Fly    70 KAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRS 134
             .||.|||...:|.|.::|.||.:||:||:|.||.|:|:|.|:|.||:|..|:.|.|..|:.:|.
  Fly    76 -GPFCGFYALLQPRALILDRELIRQIMIKDFWNFNDRGLYCNQKSDPLSGDLYALRGESWKEMRQ 139

  Fly   135 KLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKV--SENSILDVRDLVARFTVDVIGTCAFGIKCN 197
            ||..:....:|..:|..:...||:.:..::..:  ..:|.:.::.::.|:.:..:..|.||:...
  Fly   140 KLDPSLEGDRMSLLYDCLYEEAEQLLLTVNSTLMSQPHSTVHIQKIMRRYVLSSLAKCVFGLNAE 204

  Fly   198 SLRDEKAE-FLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLR 261
            ..:....| |......||...:||.|::.:|..:||..|.|.:.|...|.:|::.:::...|..|
  Fly   205 QRKTYPLEDFEQMTELALNSHKHGYLMNLMMIRFPNFCRMLRMRRTPKQAEEYFIKLLTSIVEQR 269

  Fly   262 EKENIKRNDFMDMLIGLKNQKNMT--LENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALY 324
            |.....:.|::.:||.:|..:.:|  .|..:.:.....:|:.|.|.||..||::.:::|:.:.||
  Fly   270 ETSGKPQKDYLQLLIDVKALEFITHQYEADKELGAHLQNELAAHAVVFLKAGYEQTANTLSYVLY 334

  Fly   325 ELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVV 389
            |||.:|.:|.:||.|:.:.:|:||...|:|.||.|.::.||||||||.:.|.|.:.|.....:.|
  Fly   335 ELALHPELQVRVREEVKKAIERHDGHITHEGIKSLSFMGQVINETLRMHPITPYILRRTLNDYAV 399

  Fly   390 PGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGL 454
            |.:||:::.....:|||:.||||||.|||:|.||:|:|:|....:.:....|..||.|.|:|||:
  Fly   400 PDHPKYILVKELFLIIPTHAIHHDPDIYPDPEEFKPDRWSGPRDSLQEQGTWFGFGVGARSCIGI 464

  Fly   455 RFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQL 502
            :|.|:|.|:.||:|:..:.||..:..|           |:.::.||.|
  Fly   465 QFAQLQLRLALALLLSEYEFSLNTRKP-----------LINLEDGIAL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	155/475 (33%)
Cyp317a1	NP_001286435.1	p450	39..466	CDD:299894	141/427 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471837
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	10	9.900