Protein Alignment Cyp6a18 and Cyp49a1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_610588.2
• Gene: Cyp49a1 / 36105
• FlyBaseID: FBgn0033524
• Length: 589
• Species: Drosophila melanogaster
• Alignment Length: 559
• Identity: 126/559 - (22%)
• Similarity: 191/559 - (34%)
• Gaps: 185/559 - (33%)

  Fly    34 IPYDKPHPLRGN-------MEGYKKT---RTVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVID 88
            :|...|.||.||       :..||.:   :.::|:|..|      .|...||..:......||.|
  Fly   103 VPGPYPLPLIGNSWRFAPLIGTYKISDLDKVMNELHVNY------GKMAKVGGLIGHPDLLFVFD 161

  Fly    89 LELAKQILIKNFSNFTDKGIYYNEKDDPMS-----------------------AHLFNLDGPQWR 130
            .:..:.|.               :|::.|.                       |.|..:.||:|.
  Fly   162 GDEIRNIF---------------KKEEAMPHRPSMPSLRHYKGDLRRDFFGDVAGLIGVHGPKWE 211

  Fly   131 LLRSKLSSTFTSGKMKFMY-PTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGI 194
            ..|.::.......:....| |.:..:|.|||.
  Fly   212 AFRQEVQHILLQPQTAKKYIPPLNDIASEFMG--------------------------------- 243

  Fly   195 KCNSLRDEK----AEFLH---------FGRRALLDSRHGNL--------------VSGLMRSYPN 232
            :...:||||    |.|||         .| |..||:|.|.|              ::....:.|.
  Fly   244 RIELMRDEKDELPANFLHELYKWALESVG-RVSLDTRLGCLSPEGSEEAQQIIEAINTFFWAVPE 307

  Fly   233 LARRLGLCR--NTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKN-QKNMTLENGEVVKG 294
            |..|:.|.|  .|...:.|.:.:.:.|.                 |.:|| .|.|...:.:..:|
  Fly   308 LELRMPLWRIYPTKAYRSFVKALDQFTA-----------------ICMKNIGKTMDKADADEARG 355

  Fly   295 LTMDE--------IVAQ----------AFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELG 341
            |:..|        ||.:          |...|:.|.||:|......:|:|||||..|.|:..||.
  Fly   356 LSKSEADISIVERIVRKTGNRKLAAILALDLFLVGVDTTSVAASSTIYQLAKNPDKQKKLFDELQ 420

  Fly   342 QVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIP 406
            :|....:.......::.:.||...:.||||...:|....|......|:.|   :.:..|..||.|
  Fly   421 KVFPHREADINQNVLEQMPYLRACVKETLRMRPVVIANGRSLQSDAVING---YHVPKGTHVIFP 482

  Fly   407 SSAIHHDPSIYPEPNEFRPERF---------SPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQAR 462
            ...:.:||:.:|||..|.|||:         .|..:.|......||||.|.|.|:|.||.:::..
  Fly   483 HLVVSNDPAYFPEPKRFLPERWLKQSTDAAGCPHANQKIHPFVSLPFGFGRRMCVGRRFAEIELH 547

  Fly   463 IGLAMLIK---------------NFTFSPCSATPDPLTF 486
            ..||.:.:               |.|:.|.|    ||.|
  Fly   548 TLLAKIFRKYKVSYNSGEFVYRVNSTYIPQS----PLNF 582

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	115/513 (22%)
Cyp49a1	NP_610588.2	CYP24A1-like	138..581	CDD:410677	115/521 (22%)