Protein Alignment Cyp6a18 and Cyp6u1

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001286149.1
• Gene: Cyp6u1 / 35608
• FlyBaseID: FBgn0033121
• Length: 488
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 174/509 - (34%)
• Similarity: 271/509 - (53%)
• Gaps: 26/509 - (5%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEG-YKKTRTVHEIHQEYYN 64
            |.|.:.....|:..|::|..::...|.|:|||||.::||..|.||::| ....|...:..|:.|.
  Fly     1 MDLMHRTLLTALGALSVVYALVKFSLGYWKRRGILHEKPKFLWGNIKGVVSGKRHAQDALQDIYT 65

  Fly    65 KYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQW 129
            .|: .:|||||||...||....:||:|..||:..:..:||.:|:|.|...:|:|.:|..|||.:|
  Fly    66 AYK-GRAPFVGFYACLKPFILALDLKLVHQIIFTDAGHFTSRGLYSNPSGEPLSHNLLQLDGHKW 129

  Fly   130 RLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGI 194
            |.|.:|.:..||...|:.:...:..::......:.||..:.  :::.:||..:..||:.:.|||:
  Fly   130 RSLHAKSAEVFTPANMQKLLVRLSQISSRIQRDLGEKSLQT--INISELVGAYNTDVMASMAFGL 192

  Fly   195 KCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVT 259
                :..:..||..:.|....|.|.......|  .:|.:||.|...........::|::....:.
  Fly   193 ----VGQDNVEFAKWTRNYWADFRMWQAYLAL--EFPLIARLLQYKSYAEPATAYFQKVALSQLQ 251

  Fly   260 L-REKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFAL 323
            | |.::......|:.:           ..|.|  |.||..||..|||.|.:||....::|:.|.|
  Fly   252 LHRRRDRQPLQTFLQL-----------YSNAE--KPLTDIEIAGQAFGFVLAGLGPLNATLAFCL 303

  Fly   324 YELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFV 388
            ||||:.|.:||:.|.|:.:.||:|..:.|.||:::|:|..||:|||||.:|..|.:.|.|.|.|.
  Fly   304 YELARQPEVQDRTRLEINKALEEHGGQVTPECLRELRYTKQVLNETLRLHTPHPFLLRRATKEFE 368

  Fly   389 VPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIG 453
            |||: .|||..|.:|:||::|||.||.||..|..|.||||..:....||:.|:||||:|.|.||.
  Fly   369 VPGS-VFVIAKGNNVLIPTAAIHMDPGIYENPQRFYPERFEEQARRSRPAAAFLPFGDGLRGCIA 432

  Fly   454 LRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKGGIQLKVEAI 507
            .||.:.|..:||..|::...::|.:.|..|:.:| :..:||..|..|:|.||.:
  Fly   433 ARFAEQQLLVGLVALLRQHRYAPSAETSIPVEYD-NRRLLLMPKSDIKLSVERV 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	160/467 (34%)
Cyp6u1	NP_001286149.1	p450	38..475	CDD:299894	157/460 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45471848
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
	9	8.900