Protein Alignment Cyp6a18 and Cyp6t1

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_608457.1
• Gene: Cyp6t1 / 33127
• FlyBaseID: FBgn0031182
• Length: 529
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 160/509 - (31%)
• Similarity: 255/509 - (50%)
• Gaps: 43/509 - (8%)

  Fly    15 LAIVT-----YILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKA--- 71
            |.:||     .|||  ..:::|.|:|:....|..||:  :...|.......::...|.:.:|
  Fly    29 LLVVTIVWLWQILH--FWHWRRLGVPFVPAAPFVGNV--WNLLRGACCFGDQFRELYESKEAAGR 89

  Fly    72 PFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPM-----SAHLFNLDGPQWRL 131
            .|||..:....|..:.|..|.|:|::::|:.|:.:    .|..||.     |.:||......||.
  Fly    90 AFVGIDVLHNHALLLRDPALIKRIMVEDFAQFSSR----FETTDPTCDTMGSQNLFFSKYETWRE 150

  Fly   132 LRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVS--ENSILDVRDLVARFTVDVIGTCAFGI 194
            .....:..|.:||::.||..:.::.::....|.:|:|  ::..|:|:.|.|.||.|:|.:.||||
  Fly   151 THKIFAPFFAAGKVRNMYGLLENIGQKLEEHMEQKLSGRDSMELEVKQLCALFTTDIIASLAFGI 215

  Fly   195 KCNSLRDEKAEFLHFGRRALL---DSRHGNLVS-GLMRSYPNLARRLGLCRNTAQIQEFYQRIVK 255
            :.:||::.:|||    ||..:   |.|...|:. ..|..:|.|:.|:|....:.:.:.|.::.:.
  Fly   216 EAHSLQNPEAEF----RRMCIEVNDPRPKRLLHLFTMFFFPRLSHRVGTHLYSEEYERFMRKSMD 276

  Fly   256 ETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMG 320
            ..::.|.:....|:|.:|:.:.||.     .|..|.:.. ..|...|||....:|||||||||:.
  Fly   277 YVLSQRAESGENRHDLIDIFLQLKR-----TEPAESIIH-RPDFFAAQAAFLLLAGFDTSSSTIT 335

  Fly   321 FALYELAKNPSIQDKVRAELGQVLE-QHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAA 384
            |||||||||.:|||::|.||...|: ..|::.:.:.:..|.||.||::|.||.|.....:||...
  Fly   336 FALYELAKNTTIQDRLRTELRAALQSSQDRQLSCDTVTGLVYLRQVVDEVLRLYPPTAFLDRCCN 400

  Fly   385 KRF---VVP--GNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPF 444
            .|.   :.|  |...|.:.||..|.|....||.|...:|.|..|.|||||.|:..:...:.:|||
  Fly   401 SRTGYDLSPWNGGSPFKLRAGTPVYISVLGIHRDAQYWPNPEVFDPERFSAEQRQQHHPMTYLPF 465

  Fly   445 GEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIKG 498
            |.|||.|||...||::.::||..::.:|....|..|...:.|||.:.:|....|
  Fly   466 GAGPRGCIGTLLGQLEIKVGLLHILNHFRVEVCERTLPEMRFDPKAFVLTAHNG 519

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	151/481 (31%)
Cyp6t1	NP_608457.1	p450	91..515	CDD:299894	143/437 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45461066
Domainoid	1	1.000	151	1.000	Domainoid score	I1386
eggNOG	1	0.900	-	-		E2759_KOG0158
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	161	1.000	Inparanoid score	I1621
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		otm3438
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	9	8.900