Protein Alignment Cyp6a18 and cyp26b1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_997831.1
• Gene: cyp26b1 / 324188
• ZFINID: ZDB-GENE-030131-2908
• Length: 511
• Species: Danio rerio
• Alignment Length: 474
• Identity: 111/474 - (23%)
• Similarity: 191/474 - (40%)
• Gaps: 81/474 - (17%)

  Fly    10 VAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNM---------------EGYKKTRTVHEIH 59
            |::|||..|:..|. :|.:...|......|.| :|:|               .|:..:|     .
Zfish    20 VSMALLLAVSQQLW-QLRWTATRDKSCKLPMP-KGSMGFPIIGETCHWFFQGAGFHASR-----R 77

  Fly    60 QEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSA----- 119
            |:|.|.::.        :|..:|...|...|..:::|:...|..|        .|.|.|.
Zfish    78 QKYGNVFKT--------HLLGRPLIRVTGAENVRKVLMGEHSLVT--------VDWPQSTSTLLG 126

  Fly   120 --HLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARF 182
              .|.|..|...|..|...:..|:...::...|.:..|.:|.:.|..   |....::|.....|.
Zfish   127 PNSLANSIGDIHRKRRKIFAKVFSHEALESYLPKIQQVIQETLRVWS---SNPDPINVYRESQRL 188

  Fly   183 TVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQ 247
            :.::......|.:   :.:|:...|....:..:::     |..|....|....|.|:     :.:
Zfish   189 SFNMAVRVLLGFR---IPEEEMHCLFSTFQEFVEN-----VFSLPIDLPFSGYRKGI-----RAR 240

  Fly   248 EFYQRIVKETVTLREKE-NIKRNDFMDML-IGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIA 310
            :..|:.:::.:  |||. :.:..|:.|.| :.|::.|....|       |||.|:.........|
Zfish   241 DSLQKSIEKAI--REKPLHTQGKDYTDALDVLLESAKENNTE-------LTMQELKESTIELIFA 296

  Fly   311 GFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHD-----QKFTYECIKDLKYLDQVINETL 370
            .|.|::|.....:.:|.::|::.:|:|.||......||     .:...:.|..|||||.||.|.|
Zfish   297 AFATTASASTSLVMQLLRHPAVLEKLREELRSCGLLHDGCLCQGELRLDSIISLKYLDCVIKEVL 361

  Fly   371 RHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAK 435
            |.:..|....|:|.:.|.:.|   ..:..|.||:......|...:::.:...|.|:|||||.|..
Zfish   362 RLFAPVSGGYRIATQTFELDG---VQVPKGWSVMYSIRDTHDTSAVFKDVEAFDPDRFSPERSED 423

  Fly   436 RPS-VAWLPFGEGPRNCIG 453
            |.. ..:||||.|.|:|:|
Zfish   424 REGRFHYLPFGGGVRSCLG 442

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	94/399 (24%)
cyp26b1	NP_997831.1	cytochrome_P450	60..489	CDD:477761	99/432 (23%)