Protein Alignment Cyp6a18 and Cyp26b1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_851601.2
• Gene: Cyp26b1 / 312495
• RGDID: 631379
• Length: 512
• Species: Rattus norvegicus
• Alignment Length: 547
• Identity: 118/547 - (21%)
• Similarity: 204/547 - (37%)
• Gaps: 113/547 - (20%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDK----PHPLRGNM--------------- 46
            ::|...|..:|..|:::...:...:..:..|.....||    |.| :|:|
  Rat     6 LELVSALATLAACLVSVTLLLAVSQQLWQLRWAATRDKSCKLPIP-KGSMGFPLIGETGHWLLQG 69

  Fly    47 EGYKKTRTVHEIHQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYN 111
            .|::.:|     .::|.|.::.        :|..:|...|...|..::||:......:.:.
  Rat    70 SGFQSSR-----REKYGNVFKT--------HLLGRPLIRVTGAENVRKILLGEHQLVSTEW---- 117

  Fly   112 EKDDPMSAHLF-------NLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFM-AVMHEKVS 168
                |.||.:.       |..|...|..|...|..|:...::...|.:..|.::.: |...:..:
  Rat   118 ----PRSARVLLGPNTVANSIGDIHRNKRKVFSKIFSHEALESYLPKIQLVIQDTLRAWSSQPEA 178

  Fly   169 ENSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNL----------V 223
            .|...:.:.|..|..|.|:  ..|.|....|                    |||          |
  Rat   179 INVYQEAQRLTFRMAVRVL--LGFSIPEEDL--------------------GNLFEVYQQFVENV 221

  Fly   224 SGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLREK----ENIKRNDFMDMLIGLKNQKNM 284
            ..|....|....|.|:     |.::..|:.:::.:  |||    :....:|.:|:||      ..
  Rat   222 FSLPVDLPFSGYRRGI-----QARQILQKGLEKAI--REKLQCTQGKDYSDALDILI------ES 273

  Fly   285 TLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQH-- 347
            :.|:|   |.:||.|:.........|.:.|::|.....:.:|.|:|::.:|:|.||......|
  Rat   274 SKEHG---KEMTMQELKDGTLELIFAAYATTASASTSLIMQLLKHPAVLEKLREELRAQGLLHGG 335

  Fly   348 ----DQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSS 408
                :.....:.:..|:|||.||.|.:|.:|.|....|...:.|.:.|   |.|..|.||:....
  Rat   336 GCPCEGTLRLDMLSGLRYLDCVIKEVMRLFTPVSGGYRTVLQTFELDG---FQIPKGWSVMYSIR 397

  Fly   409 AIHHDPSIYPEPNEFRPERFSPEESA-KRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNF 472
            ..|....::.:.|.|.|:|||...|. |.....:||||.|.|.|:|....::..::....|....
  Rat   398 DTHDTAPVFKDVNVFDPDRFSQARSEDKDGRFHYLPFGGGVRTCLGKHLAKLFLKVLAVELASTS 462

  Fly   473 TFSPCSATPDPLTFDP--HSAILLGIK 497
            .|...:.|...:|..|  |....|.:|
  Rat   463 RFELATRTFPRITLVPVLHPVDGLSVK 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	103/459 (22%)
Cyp26b1	NP_851601.2	CYP26B1	60..490	CDD:410730	107/492 (22%)