Protein Alignment Cyp6a18 and Cyp26c1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_217935.3
• Gene: Cyp26c1 / 308190
• RGDID: 1308843
• Length: 518
• Species: Rattus norvegicus
• Alignment Length: 483
• Identity: 102/483 - (21%)
• Similarity: 179/483 - (37%)
• Gaps: 116/483 - (24%)

  Fly    54 TVHEIHQ--EYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDP 116
            |:|.:.|  .:::..|.........:|..:|...|...|..:.||:........:.        |
  Rat    62 TLHWLVQGSRFHSSRRERYGTVFKTHLLGRPVIRVSGAENVRTILLGEHRLVRSQW--------P 118

  Fly   117 MSAH-------LFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILD 174
            .|||       |....|.:.|..|..|:..|:...:           |:|:..:.|.:..
  Rat   119 QSAHILLGSHTLLGAVGERHRQRRKVLARVFSRPAL-----------EQFVPRLQEALRR----- 167

  Fly   175 VRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGL 239
                      :|...||         .::...::...:||.......::.||         :|..
  Rat   168 ----------EVRSWCA---------AQRPVAVYQAAKALTFRMAARILLGL---------QLDE 204

  Fly   240 CRNTAQIQEFYQRIVKETVTL-------REKENIKRND----FMDMLIGLKNQKNMTLENG---- 289
            .|.| ::.:.::|:|:...:|       ..::.|:..|    .:|.:|..|.::.:|.|.|
  Rat   205 ARCT-ELAQTFERLVENLFSLPLDVPFSGLRKGIRARDQLYQHLDEVIAEKLREELTAEPGDALH 268

  Fly   290 -------EVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAEL-GQVL-- 344
                   |:.:.|::.|:...|.....|.|.|::|.....:..|.::|:...|::.|| .|.|
  Rat   269 LIINSARELGRELSVQELKELAVELLFAAFFTTASASTSLILLLLQHPAAIAKIQQELSAQGLGS 333

  Fly   345 ------EQHDQKFTYECIKD--------LKYLDQVINETLRHYTIVPNVD---RVAAKRFVVPGN 392
                  .....:....|..|        |:|:|.|:.|.||   ::|.|.   |.|.:.|.:.|
  Rat   334 PCSCAPRASGSRPDCSCEPDLSLAVLGRLRYVDCVVKEVLR---LLPPVSGGYRTALRTFELDG- 394

  Fly   393 PKFVIEAGQSVIIPSSAIHHDPSIYPEPNE-FRPERFSPEESAKRPS---VAWLPFGEGPRNCIG 453
              :.|..|.||:......|...::|..|.| |.||||..|....|.|   ..::|||.|.|:|:|
  Rat   395 --YQIPKGWSVMYSIRDTHETAAVYRSPPEGFDPERFGVESEDARGSGGRFHYIPFGGGARSCLG 457

  Fly   454 LRFGQMQARIGLAMLIKNFTFSPCSATP 481
            ....|...::....|::...:.  .|||
  Rat   458 QELAQAVLQLLAVELVRTARWE--LATP 483

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	98/465 (21%)
Cyp26c1	XP_217935.3	cytochrome_P450	59..504	CDD:477761	102/483 (21%)