Protein Alignment Cyp6a18 and Cyp4a3

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_038965516.1
• Gene: Cyp4a3 / 298423
• RGDID: 631356
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 544
• Identity: 133/544 - (24%)
• Similarity: 224/544 - (41%)
• Gaps: 98/544 - (18%)

  Fly     6 FLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSK 70
            ||..:.:.|...|.:.|.|:.........|....|.|.|           |::....:.:.....
  Rat    23 FLLSLFLVLFKAVQFYLRRQWLLKALEKFPSTPSHWLWG-----------HDLKDREFQQVLTWV 76

  Fly    71 APFVGFYL----FQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFN-------- 123
            ..|.|..|    ..|....:.|.:..|.:|               .:.||.::.::.
  Rat    77 EKFPGACLQWLSGSKTRVLLYDPDYVKVVL---------------GRSDPKASGIYQFLAPWIVS 126

  Fly   124 --------LDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKV-SENSILDVRDLV 179
                    |:|.:|......|:..|..|.:| .|..:::.:...|....||: .::..|::...|
  Rat   127 GTGYGLLLLNGKKWFQHWRMLTPAFHYGILK-PYVKIMADSVSIMLDKWEKLDDQDHPLEIFHYV 190

  Fly   180 ARFTVDVIGTCAFG------IKCNSLRDEKA----EFLHFGRRALLDSRHGNLVSGLMRSYPNLA 234
            :..|:|.:..|||.      :..||....||    ..|.|.|  :..:.:||.:...|.|...|:
  Rat   191 SLMTLDTVMKCAFSHQGSVQLDVNSRSYTKAVEDLNNLTFFR--VRSAFYGNSIIYNMSSDGRLS 253

  Fly   235 RRL---------GLCR-NTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENG 289
            ||.         |:.: ..||:|.     .:|....|:|.::   ||:|:|:..|      :|:|
  Rat   254 RRACQIAHEHTDGVIKMRKAQLQN-----EEELQKARKKRHL---DFLDILLFAK------MEDG 304

  Fly   290 EVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYE 354
               |.|:.:::.|:...|...|.||::|.:.:..|.||.:|..|::.|.|:..:|.. ....|::
  Rat   305 ---KSLSDEDLRAEVDTFMFEGHDTTASGISWVFYALATHPEHQERCREEVQSILGD-GTSVTWD 365

  Fly   355 CIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPE 419
            .:..:.|....|.|.||.|..||:|.|..:.....|....  |..|.:..|....:||:||.:|.
  Rat   366 HLDQISYTTMCIKEALRLYPPVPSVSRELSSPVTFPDGRS--IPKGITTTILIYGLHHNPSYWPN 428

  Fly   420 PNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPL 484
            |..|.|.||||:  :.|.|.|:|||..|.|||||.:|...:.::.:|:.:..|     ...|||.
  Rat   429 PKVFDPSRFSPD--SPRHSHAYLPFSGGARNCIGKQFAMNELKVAVALTLLRF-----ELLPDPT 486

  Fly   485 TFD-PHSAILLGIKGGIQLKVEAI 507
            ... |.:.::|..|.||.|:::.:
  Rat   487 RIPVPMARLVLKSKNGIHLRLKKL 510

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	126/507 (25%)
Cyp4a3	XP_038965516.1	CYP4B-like	69..506	CDD:410771	121/481 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900