Protein Alignment Cyp6a18 and Cyp4a12a

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_803125.2
• Gene: Cyp4a12a / 277753
• MGIID: 88612
• Length: 508
• Species: Mus musculus
• Alignment Length: 554
• Identity: 138/554 - (24%)
• Similarity: 220/554 - (39%)
• Gaps: 118/554 - (21%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEI-----HQ 60
            :.|...||:.|       ...|||:......:..|....|.|.|           |:|     .|
Mouse    25 LSLLLLLFKTA-------QLYLHRQWLLSSTQQFPSPPSHWLFG-----------HKILKDQDLQ 71

  Fly    61 EYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDP--------- 116
            :...:.:|..:....:....|....|.|.:..|.||               .:.||
Mouse    72 DILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLIL---------------GRSDPKANGSYRFL 121

  Fly   117 ---MSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK----VSENSILD 174
               :...|..|||..|...|..|:..|....:|    ....:..:.:.||.:|    |.::|.|:
Mouse   122 APWIGRGLLMLDGQTWFQHRRMLTPAFHYDILK----PYTEIMADSVRVMLDKWEQIVGQDSTLE 182

  Fly   175 VRDLVARFTVDVIGTCAFGIKCNSLRDEK-------AEFLHFGRRALLDSR-----HGNLVSGLM 227
            :...:...|:|.|..|||..:.:...|.|       .|.|:    .|:.||     |.|.:  :.
Mouse   183 IFRHITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLN----DLVFSRVRNIFHQNDI--IY 241

  Fly   228 RSYPNLARRLGLCR----NTAQIQEFYQRIVKETVTLREKENI------KRNDFMDMLIGLKNQK 282
            |...|..:....|:    :|.|:      |....:.|:::|.:      :|.||:|:|:..:
Mouse   242 RVSSNGCKANSACKLAHDHTDQV------IKSRRIQLQDEEELEKLKKKRRLDFLDILLFAR--- 297

  Fly   283 NMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQH 347
               :|||   |.|:..::.|:...|...|.||::|.:.:..|.||.||..|.:.|.|: |.|...
Mouse   298 ---MENG---KSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEI-QSLLGD 355

  Fly   348 DQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGN---PKFVIEAGQSVIIPSSA 409
            ....|:..:..:.|....|.|.||.|..||:|.|..:.....|..   ||     |..|::....
Mouse   356 GTSITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPK-----GIHVMLSFYG 415

  Fly   410 IHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTF 474
            :||:|:::|.|..|.|.||:|..|  |.|.::|||..|.|||||.:|...:.::.:|:.:..|
Mouse   416 LHHNPTVWPNPEVFDPSRFAPGSS--RHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRF-- 476

  Fly   475 SPCSATPDPLTFD-PHSAILLGIKGGIQLKVEAI 507
               ...|||.... |...|:|..|.||.|.::.:
Mouse   477 ---ELLPDPTRVPIPIPRIVLKSKNGIHLHLKKL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	130/512 (25%)
Cyp4a12a	NP_803125.2	p450	52..502	CDD:278495	130/513 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900