Protein Alignment Cyp6a18 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001129072.1
• Gene: Cyp4v3 / 266761
• RGDID: 708530
• Length: 525
• Species: Rattus norvegicus
• Alignment Length: 508
• Identity: 137/508 - (26%)
• Similarity: 219/508 - (43%)
• Gaps: 86/508 - (16%)

  Fly    10 VAVALLAIVTYILHRKLTYFKR----RGIP-YDKPHPLRGNMEGYKKTRTVHEIHQ---EYYNKY 66
            |:||...::..||...::|.::    |.|| ..:.:||.|:....|...|  |..|   :|..::
  Rat    22 VSVAGATVLLNILQMLVSYARKWQQMRPIPSVARAYPLVGHALFMKPNNT--EFFQQIIQYTEEF 84

  Fly    67 RNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRL 131
            |:  .|.:..::...|...:...|..:.||..  |...||...|......:...|....|.:||.
  Rat    85 RH--LPIIKLWIGPVPLVALYKAENVEVILTS--SKQIDKSFMYKFLQPWLGLGLLTSTGSKWRA 145

  Fly   132 LRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDV------IGTC 190
            .|..|:.:|.           .::.|:|:.||:|:.   :|| |..|......:.      |..|
  Rat   146 RRKMLTPSFH-----------FTILEDFLDVMNEQA---NIL-VNKLEKHVNQEAFNCFFPITLC 195

  Fly   191 AFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGL---------------- 239
            |..|.|     |.|...:.|.::..||.:   |..:.|....:.||:.:
  Rat   196 ALDIIC-----ETAMGKNIGAQSNGDSEY---VRTVYRMSDMIYRRMKMPWFWFDLWYLMFKEGR 252

  Fly   240 --CRNTAQIQEFYQRIVKETVTLREKE-------------NIKRNDFMDMLIGLKNQKNMTLENG 289
              .:....:..|...::.|.|..|:.|             ..||..|:|:|:.:.:::...|.:
  Rat   253 DHKKGLKSLHTFTNNVIAERVNARKAEQDCIGAGRGPLPSKTKRKAFLDLLLSVTDEEGNKLSH- 316

  Fly   290 EVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYE 354
                    ::|..:...|...|.||:::.:.::||.|..||.:|.||..||..|..:..:..|.|
  Rat   317 --------EDIREEVDTFMFEGHDTTAAAINWSLYLLGSNPEVQRKVDKELDDVFGRSHRPVTLE 373

  Fly   355 CIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPE 419
            .:|.|||||.||.||||.:..||...|..::...|.|   :.|..|...:|...|:|.||..:|:
  Rat   374 DLKKLKYLDCVIKETLRVFPSVPLFARSLSEDCEVAG---YKISKGTEAVIIPYALHRDPRYFPD 435

  Fly   420 PNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNF 472
            |.||:||||.||.|..|...|::||..|||||||.:|..|:.:..||.:::.|
  Rat   436 PEEFQPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILREF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	119/440 (27%)
Cyp4v3	NP_001129072.1	CYP4V	76..515	CDD:410773	121/452 (27%)