Protein Alignment Cyp6a18 and Cyp4f6

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_006241111.1
• Gene: Cyp4f6 / 266689
• RGDID: 708365
• Length: 538
• Species: Rattus norvegicus
• Alignment Length: 561
• Identity: 141/561 - (25%)
• Similarity: 235/561 - (41%)
• Gaps: 131/561 - (23%)

  Fly    14 LLAIVTYILHRKLTYF--------KRRGIPYDKPHP---------LRGNMEGYK----KTRTVHE 57
            ||...::||.|.|.:.        :.|..| ..|.|         ::.|.||.:    ..|...:
  Rat    24 LLGGASWILARILAWIYTFYDNCCRLRCFP-QPPKPSWFWGHLTLMKNNEEGMQFIAHLGRNFRD 87

  Fly    58 IHQEYYNK--------YRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNF-SNFTDKGIYYNEK 113
            ||..:...        :.|..||     |.|..||..     .|::.:..| ..:...|:.
  Rat    88 IHLSWVGPVYPILRLVHPNVIAP-----LLQASAAVA-----PKEMTLYGFLKPWLGDGLL---- 138

  Fly   114 DDPMSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK-----VSENSIL 173
               |||      |.:|...|..|:..|....:|    :.|.:..:.:..||.|     ...::.|
  Rat   139 ---MSA------GEKWNHHRRLLTPAFHFDILK----SYVKIFNKSVNTMHAKWQRLTAKGSARL 190

  Fly   174 DVRDLVARFTVDVIGTCAFGIKCNS------------------LRDEKAEFLHF---------GR 211
            |:.:.::..|:|.:..|.|....|.                  ::.::..||:.         ||
  Rat   191 DMFEHISLMTLDSLQKCIFSFDSNCQESNSEYIAAILELSSLIVKRQRQPFLYLDFLYYLTADGR 255

  Fly   212 --RALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDM 274
              |...|..| |....::|.     ||..|  ||..:.||          |:.:...|..||:|:
  Rat   256 RFRKACDVVH-NFTDAVIRE-----RRSTL--NTQGVDEF----------LKARAKTKTLDFIDV 302

  Fly   275 LIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAE 339
            |:..|:      |:|   |||:..:|.|:|..|...|.||::|.:.:.||.||::|..|::.|.|
  Rat   303 LLLAKD------EHG---KGLSDVDIRAEADTFMFGGHDTTASALSWILYNLARHPEYQERCRQE 358

  Fly   340 LGQVL-EQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSV 403
            :.::| ::..::..::.:..|.:|...|.|:||.:..|..:.|..::..|:|...  ||..|...
  Rat   359 VRELLRDREPEEIEWDDLAQLPFLTMCIKESLRLHPPVLLISRCCSQDIVLPDGR--VIPKGNIC 421

  Fly   404 IIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAML 468
            :|....:||:||::|:|..:.|.||.||...||..:|::||..|||||||..|...:.::.||:.
  Rat   422 VISIFGVHHNPSVWPDPEVYNPFRFDPENPQKRSPLAFIPFSAGPRNCIGQTFAMSEIKVALALT 486

  Fly   469 IKNFTFSPCSATP--DPLTFDPHSAILLGIKGGIQLKVEAI 507
            :..|...|....|  .|       .::|..:||:.|:||.:
  Rat   487 LLRFCVLPDDKEPRRKP-------ELILRAEGGLWLRVEPL 520

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	120/467 (26%)
Cyp4f6	XP_006241111.1	CYP4F	75..516	CDD:410772	125/503 (25%)