Protein Alignment Cyp6a18 and Tbxas1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_036819.1
• Gene: Tbxas1 / 24886
• RGDID: 3826
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 532
• Identity: 152/532 - (28%)
• Similarity: 261/532 - (49%)
• Gaps: 58/532 - (10%)

  Fly    10 VAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFV 74
            ::|.|||::.:......:..::.||.:.:|.|..||:..::  :...|.|.|...:|    .|..
  Rat    20 LSVVLLALLKWYSTSAFSRLRKLGIRHPEPSPFVGNLMFFR--QGFWESHLELRERY----GPLC 78

  Fly    75 GFYLFQKPAAFVIDLELAKQILIKNFSNFTDK---GIYYNEKDDP--MSAHLFNLDGPQWRLLRS 134
            |:||.::....:.|.::.|::|::|||||:::   |:      :|  ::..:..|...:|..:|.
  Rat    79 GYYLGRRMYIVISDPDMIKEVLVENFSNFSNRMASGL------EPKLIADSVLMLRDRRWEEVRG 137

  Fly   135 KLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIKCNSL 199
            .|.|.|:..|:..|.|.:....|..::.:....:.....|::.....||.:|:.:.||||:.||.
  Rat   138 ALMSAFSPEKLNEMTPLISQACELLLSHLKHSAASGDAFDIQRCYCCFTTNVVASVAFGIEVNSQ 202

  Fly   200 RDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPN----LARRLGLCRNTAQIQEFYQRIVKETVTL 260
            ...:..|:...:|....|....|:: |:.|:|:    |||.|. .:|..::..|:..:::..:.|
  Rat   203 DAPEDPFVQHCQRVFAFSTPRPLLA-LILSFPSIMVPLARILP-NKNRDELNGFFNTLIRNVIAL 265

  Fly   261 REKENI--KRNDFMDMLIGLKNQKNMT-------------LENGE-------------VVKGLTM 297
            |:|:..  :|.||:.|:  |..|::|:             |.:.|             ..|.||:
  Rat   266 RDKQTAEERRGDFLQMV--LDAQRSMSSVGVEAFDMVTEALSSAECMGDPPQRCHPTSTAKPLTV 328

  Fly   298 DEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYL 362
            |||..|||:|.|||.:.:::|:.|..|.||.:|..|:::..|:...:|:|.........:.|.||
  Rat   329 DEIAGQAFLFLIAGHEITTNTLSFITYLLATHPECQERLLKEVDLFMEKHPAPEYCNLQEGLPYL 393

  Fly   363 DQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPER 427
            |.|:.||||.|.......|.||:...|.|..   |.||..:.|...|:||||..:|.|..|.|||
  Rat   394 DMVVAETLRMYPPAFRFTREAAQDCEVLGQH---IPAGSVLEIAVGALHHDPEHWPNPETFDPER 455

  Fly   428 FSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAI 492
            |:.|...::....:||||.|||:|:|:|.|.:..::.|..::..|.|..|..|..||..:..||
  Rat   456 FTAEARLQQKPFTYLPFGAGPRSCLGVRLGLLVVKLTLLQVLHKFRFEACPETQVPLQLESKSA- 519

  Fly   493 LLGIKGGIQLKV 504
             |..|.|:.:|:
  Rat   520 -LCPKNGVYVKI 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	136/466 (29%)
Tbxas1	NP_036819.1	cytochrome_P450	74..527	CDD:477761	138/471 (29%)