Protein Alignment Cyp6a18 and Cyp4x1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_663708.1
• Gene: Cyp4x1 / 246767
• RGDID: 628719
• Length: 507
• Species: Rattus norvegicus
• Alignment Length: 530
• Identity: 138/530 - (26%)
• Similarity: 243/530 - (45%)
• Gaps: 73/530 - (13%)

  Fly     7 LFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRG--------NMEGYKKTRTVHEIHQEYY 63
            :|.:|:.|:..|...|.|:......|..|....|.|.|        |||      .:.||.:||.
  Rat    19 VFCLALVLMQAVKLYLRRQRLLRDLRPFPGPTAHWLLGHQKFLQEDNME------KLDEIVKEYP 77

  Fly    64 NKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTD-KGIYYNEKDDP-MSAHLFNLDG 126
            ..:.....||..|:       ::.|.:.||..|.:     || |..|.::...| :...|.||||
  Rat    78 CAFPCWVGPFQAFF-------YIYDPDYAKIFLSR-----TDPKTQYLHQLMTPFLGRGLLNLDG 130

  Fly   127 PQWRLLRSKLSSTFTSGKMKFMYPTVVSVAE--EFMAVMHEK--VSENSILDVRDLVARFTVDVI 187
            |:|...|..|:..|....:|   |.|..:|.  ..|....||  .::.:.::|.:.:...|:|:|
  Rat   131 PRWFQHRCLLTPAFHQDILK---PCVDMMAHSVNMMLDKWEKTWTTQETTIEVFEHINLMTLDII 192

  Fly   188 GTCAFGIKCNSLRD------EKAEFLHFGRRALLDSR------HGNLVSGLM---RSYPNLARRL 237
            ..||||.:.|...:      .||.| ..|.  ::.||      |.:::..|.   ..:..|.:.:
  Rat   193 MKCAFGQETNCQINGTYESYVKATF-ELGE--IISSRLYNFWHHHDIIFKLSPKGHCFQELGKVI 254

  Fly   238 GLCRNTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVA 302
            ..|  |.:|.:..::.:|:.|  .:.:.....:|:|::        ::.:.|: .|..:..::.:
  Rat   255 HQC--TEKIIQDRKKTLKDQV--NQDDTQTSQNFLDIV--------LSAQAGD-EKAFSDADLRS 306

  Fly   303 QAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVIN 367
            :...|..||.|.|::::.:.||.||.||..||:.|.|:..:|.. ....|:|.:.::.|....|.
  Rat   307 EVNTFMWAGHDASAASISWLLYCLALNPEHQDRCRTEIRSILGD-GSSITWEQLDEIPYTTMCIK 370

  Fly   368 ETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEE 432
            ||||....:|::.|..:|...:|....  :.||.:|::....:||:|:::.:|..|.|.||:.|.
  Rat   371 ETLRLIPPIPSISRELSKPLTLPDGHS--LPAGMTVVLSIWGLHHNPAVWKDPKVFDPLRFTKEN 433

  Fly   433 SAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHSAILLGIK 497
            |.:|...|:|||..|||||||.:|..::.::.:|:.:..|..:  :....|..|..|:  :|..|
  Rat   434 SEQRHPCAFLPFSSGPRNCIGQQFAMLELKVAIALTLLRFRVA--ADLTRPPAFSSHT--VLRPK 494

  Fly   498 GGIQLKVEAI 507
            .||.|.::.:
  Rat   495 HGIYLHLKKL 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	117/450 (26%)
Cyp4x1	NP_663708.1	CYP4B-like	66..500	CDD:410771	125/477 (26%)