Protein Alignment Cyp6a18 and Cyp4b1

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 130/541 - (24%)
• Similarity: 222/541 - (41%)
• Gaps: 104/541 - (19%)

  Fly    12 VALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEI---HQEYYNKYRNSKAPF 73
            |.:|.:.:.:|.|:.........|....|.|.|:....:|..::.::   .|::.:.:......|
  Rat    24 VIVLKLFSLLLRRQKLARAMDSFPGPPTHWLFGHALEIQKLGSLDKVVSWAQQFPHAHPLWFGQF 88

  Fly    74 VGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFN------------LDG 126
            |||....:|       :.||.:.               .:.||.:|.:::            |||
  Rat    89 VGFLNIYEP-------DYAKAVY---------------SRGDPKAADVYDFFLQWIGKGLLVLDG 131

  Fly   127 PQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVM---HEKVSENSILDVRDLVARFTVDVIG 188
            |:|...|..|:..|....:|   |.|...||....::   .:|.|||...|:...|....:|.:.
  Rat   132 PKWFQHRKLLTPGFHYDVLK---PYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLM 193

  Fly   189 TCAFGIKCNSL--RDEKAEFLHFGRRALLDSR------HGNLVSGLMRSYPNLARRLGLCR---- 241
            .|.||...:.|  ||............|:..|      |.:.:..|.   |:..|.|..|:
  Rat   194 KCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLT---PHGRRFLRACKIAHD 255

  Fly   242 --------NTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMD 298
                    ..|.:|:     .||...::::.::   ||:|:|:|::::..:.|.:.
  Rat   256 HTDEVIRQRKAALQD-----EKERKKIQQRRHL---DFLDILLGVRDESGIKLSDA--------- 303

  Fly   299 EIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLD 363
            |:.|:...|...|.||::|.:.:.||.:|..|..|...|.|:..:|...| .|.::.:..:.||.
  Rat   304 ELRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQD-SFQWDDLAKMTYLT 367

  Fly   364 QVINETLRHYTIVPNVDRVAAKRFV-VPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPER 427
            ..:.|..|.|..||.|.|...|... |.|..   :.||..:.:...|:|.:.:::|:|..|.|.|
  Rat   368 MCMKECFRLYPPVPQVYRQLNKPVTFVDGRS---LPAGSLISLHIYALHRNSTVWPDPEVFDPLR 429

  Fly   428 FSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHS-- 490
            ||||.:|.|...|::||..|||||||.:|...:.::..|:.:..|.||          .||..
  Rat   430 FSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFS----------LDPSKMP 484

  Fly   491 ----AILLGIKGGIQLKVEAI 507
                .::|..|.||.|.::.:
  Rat   485 IKVPQLILRSKNGIHLYLKPL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	125/510 (25%)
Cyp4b1	NP_058695.2	p450	47..500	CDD:278495	125/511 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.900