Protein Alignment Cyp6a18 and Cyp4b1

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_058695.2
• Gene: Cyp4b1 / 24307
• RGDID: 2480
• Length: 511
• Species: Rattus norvegicus
• Alignment Length: 541
• Identity: 130/541 - (24%)
• Similarity: 222/541 - (41%)
• Gaps: 104/541 - (19%)

  Fly    12 VALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEI---HQEYYNKYRNSKAPF 73
            |.:|.:.:.:|.|:.........|....|.|.|:....:|..::.::   .|::.:.:......|
  Rat    24 VIVLKLFSLLLRRQKLARAMDSFPGPPTHWLFGHALEIQKLGSLDKVVSWAQQFPHAHPLWFGQF 88

  Fly    74 VGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFN------------LDG 126
            |||....:|       :.||.:.               .:.||.:|.:::            |||
  Rat    89 VGFLNIYEP-------DYAKAVY---------------SRGDPKAADVYDFFLQWIGKGLLVLDG 131

  Fly   127 PQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVM---HEKVSENSILDVRDLVARFTVDVIG 188
            |:|...|..|:..|....:|   |.|...||....::   .:|.|||...|:...|....:|.:.
  Rat   132 PKWFQHRKLLTPGFHYDVLK---PYVAIFAESTRMMLDKWEKKASENKSFDIFCDVGHMALDTLM 193

  Fly   189 TCAFGIKCNSL--RDEKAEFLHFGRRALLDSR------HGNLVSGLMRSYPNLARRLGLCR---- 241
            .|.||...:.|  ||............|:..|      |.:.:..|.   |:..|.|..|:
  Rat   194 KCTFGKGDSGLGHRDNSYYLAVSDLTLLMQQRIDSFQYHNDFIYWLT---PHGRRFLRACKIAHD 255

  Fly   242 --------NTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMD 298
                    ..|.:|:     .||...::::.::   ||:|:|:|::::..:.|.:.
  Rat   256 HTDEVIRQRKAALQD-----EKERKKIQQRRHL---DFLDILLGVRDESGIKLSDA--------- 303

  Fly   299 EIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLD 363
            |:.|:...|...|.||::|.:.:.||.:|..|..|...|.|:..:|...| .|.::.:..:.||.
  Rat   304 ELRAEVDTFMFEGHDTTTSGISWFLYCMALYPEHQQLCREEVRGILGDQD-SFQWDDLAKMTYLT 367

  Fly   364 QVINETLRHYTIVPNVDRVAAKRFV-VPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPER 427
            ..:.|..|.|..||.|.|...|... |.|..   :.||..:.:...|:|.:.:::|:|..|.|.|
  Rat   368 MCMKECFRLYPPVPQVYRQLNKPVTFVDGRS---LPAGSLISLHIYALHRNSTVWPDPEVFDPLR 429

  Fly   428 FSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTFDPHS-- 490
            ||||.:|.|...|::||..|||||||.:|...:.::..|:.:..|.||          .||..
  Rat   430 FSPENAAGRHPFAFMPFSAGPRNCIGQQFAMNEMKVVTALCLLRFEFS----------LDPSKMP 484

  Fly   491 ----AILLGIKGGIQLKVEAI 507
                .::|..|.||.|.::.:
  Rat   485 IKVPQLILRSKNGIHLYLKPL 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	117/471 (25%)
Cyp4b1	NP_058695.2	CYP4B-like	67..501	CDD:410771	120/492 (24%)