Protein Alignment Cyp6a18 and cyp-13A2

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_496109.1
• Gene: cyp-13A2 / 188360
• WormBaseID: WBGene00011676
• Length: 515
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 148/521 - (28%)
• Similarity: 242/521 - (46%)
• Gaps: 65/521 - (12%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIH-QEYYN 64
            |.|.:.|.......|.|:||.|. ..||:.|:|:...:..|..|.::...:..|...|. .|:..
 Worm     1 MSLGFVLAVTFSIFLGILTYYLW-IWTYWMRKGVKGPRGRPFVGVLDVLLEHETPGLIKLGEWTK 64

  Fly    65 KYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMS--------AHL 121
            ||    ....|:....:....|.|..:..:|.:|.|.||      |..|.:|:.        .||
 Worm    65 KY----GKVYGYTDGTQRTLVVADPAMVHEIFVKQFDNF------YGRKLNPIQGNPEKEQRVHL 119

  Fly   122 FNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDV 186
            ....|.:|:.||:..|.:|::..:|.|..||...|.|.:..:.::.:....:|:......:|:||
 Worm   120 LAAQGYRWKRLRTISSQSFSNASLKKMKRTVEDSALELLRHIEKQTAGGEQIDMLRFYQEYTMDV 184

  Fly   187 IGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRH------------GNLVSGLMRSYPNLARRLGL 239
            ||..|.| :.:|:. .|...::..|.....||.            |..:..|...:|.:.
 Worm   185 IGRFAMG-QTDSMM-FKNPIVNVVREIFCGSRKNLMLICQVFPPIGQFIRDLTFKFPRIP----- 242

  Fly   240 CRNTAQIQEFYQRIVKETVTLREK----ENIKRNDFMDMLIGLKN---------QKNMTLENGEV 291
               ..::....|.:|...:..||:    |:.:..||:|:.:..::         :::.:..|.::
 Worm   243 ---AFKLYSIMQDVVAARIAQREREKGAESGEPQDFIDLFLDARSDDVDFSAEAREDFSKRNLKI 304

  Fly   292 VKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECI 356
            .|.|:.||:|.|.|:|.|.||||::.::.:..|.||.||.||:||..|:.:  |....:..:|.:
 Worm   305 TKELSADEVVGQCFLFLIGGFDTTALSLSYVTYLLAVNPKIQEKVIEEIAR--EFGTSEVEFEKL 367

  Fly   357 KDLKYLDQVINETLRHYTI--VPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPE 419
            ..|||:|.||.|.||.|.:  :.| .|...|...|.|   ..||||..|.:.:.::|:||.::.|
 Worm   368 GRLKYMDCVIKEALRLYPLASISN-SRKCMKTTTVNG---VKIEAGVYVQMDTWSLHYDPELWGE 428

  Fly   420 P-NEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDP 483
            . .||:|||:|.:|..:... |:||||.|||.|||:|...|:.:|.|..|:||:||...:.|..|
 Worm   429 DVKEFKPERWSTDEPLEHKG-AYLPFGLGPRQCIGMRLAIMEQKILLTHLLKNYTFETGNKTRIP 492

  Fly   484 L 484
            |
 Worm   493 L 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	129/451 (29%)
cyp-13A2	NP_496109.1	CYP3A-like	65..508	CDD:410678	131/456 (29%)