Protein Alignment Cyp6a18 and cyp-13A5

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_496112.1
• Gene: cyp-13A5 / 188356
• WormBaseID: WBGene00011672
• Length: 520
• Species: Caenorhabditis elegans
• Alignment Length: 549
• Identity: 147/549 - (26%)
• Similarity: 247/549 - (44%)
• Gaps: 93/549 - (16%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYN- 64
            |.|:..:  ...:.:.::||.:. ..:::.|:|:...:..|..|         .:||. |:|.|
 Worm     1 MSLSILI--AGASFIGLLTYYIW-IWSFWIRKGVKGPRGFPFFG---------VIHEF-QDYENP 52

  Fly    65 ------KYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMS----- 118
                  ::.....|..|.....:....|.:.|...::.:|.|.||      |..|.:|:.
 Worm    53 GLLKLGEWTKEYGPIYGITEGVEKTLIVSNPEFVHEVFVKQFDNF------YGRKTNPIQGDPNK 111

  Fly   119 ---AHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVA 180
               |||.:..|.:|:.||:..|.||::..::.:..||.....|.|..:.:..::...:|:.|...
 Worm   112 NKRAHLVSAQGHRWKRLRTLSSPTFSNKNLRKIMSTVEETVVELMRHLDDASAKGKAVDLLDYYQ 176

  Fly   181 RFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQ 245
            .||:|:||..|.|         :.|.|.| |..:|....|....|  |..|.|...:.....| .
 Worm   177 EFTLDIIGRIAMG---------QTESLMF-RNPMLPKVKGIFKDG--RKLPFLVSGIFPIAGT-M 228

  Fly   246 IQEFYQRI------------VKETVTLR-------EKENIKRN----DFMDMLIGLKNQKNM--- 284
            .:||:.|.            |::.:..|       ||..|:.:    ||:|:.:..:...:.
 Worm   229 FREFFMRFPSIQPAFDIMSTVEKALNKRLEQRAADEKAGIEPSGEPQDFIDLFLDARANVDFFEE 293

  Fly   285 -------TLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQ 342
                   ..|..:|.|.||.|||:.|.|||.:||:||::.::.::.|.||::|.||.|::.|:.:
 Worm   294 ESALGFAKTEIAKVDKQLTFDEIIGQLFVFLLAGYDTTALSLSYSSYLLARHPEIQKKLQEEVDR 358

  Fly   343 VLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNV-DRVAAKRFVVPGNPKFVIEAGQSVIIP 406
              |..:.:.|::.|..|||::.|:.|.||.|.:...| :|...|...|.|   ..||.|.:|.:.
 Worm   359 --ECPNPEVTFDQISKLKYMECVVKEALRMYPLASIVHNRKCMKETNVLG---VQIEKGTNVQVD 418

  Fly   407 SSAIHHDPSIYPE-PNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIK 470
            :..:|:||.::.| .|||||||:...:........:||||.|||.|||:|...|:.::.|..::|
 Worm   419 TWTLHYDPKVWGEDANEFRPERWESGDELFYAKGGYLPFGMGPRICIGMRLAMMEKKMLLTHILK 483

  Fly   471 NFTFSPCSATPDPL------TFDPHSAIL 493
            .:||...:.|..||      |..|.|.:|
 Worm   484 KYTFETSTQTEIPLKLVGSATTAPRSVML 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	141/512 (28%)
cyp-13A5	NP_496112.1	p450	33..514	CDD:278495	141/514 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4759
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.730