DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cyp6a18 and cyp-25A6

DIOPT Version :9

Sequence 1:	NP_001287562.1	Gene:	Cyp6a18 / 43304	FlyBaseID:	FBgn0039519	Length:	507	Species:	Drosophila melanogaster
Sequence 2:	NP_001360017.1	Gene:	cyp-25A6 / 187059	WormBaseID:	WBGene00019438	Length:	235	Species:	Caenorhabditis elegans

Alignment Length:	221	Identity:	65/221 - (29%)
Similarity:	110/221 - (49%)	Gaps:	8/221 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LFQVAVALLAIVTYILHRKLTYFKRR---GIPYDKPHPLRGNMEGY--KKTRTVHEIHQEYYNKY 66
            |..:.|:|::.:.|::..:...|:.|   |:...:||.|.||::..  :|.:..::...::|||.
Worm     6 LTSILVSLVSFIIYVILARKERFRLRGKIGLSGPEPHWLMGNLKQIIERKAKLGYDDSYDWYNKL 70

  Fly    67 RNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLF-NLDGPQWR 130
            ........|.|...:....:.:.|..|::.|||||||:|:......:|:.:...|. |.....|:
Worm    71 HKQFGETFGIYFGTQLNINITNEEDIKEVFIKNFSNFSDRTPPPIIEDNKLKESLLQNTYESGWK 135

  Fly   131 LLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIK 195
            ..||.::..|::||||.|:.|:.|..:.|:.::.||.|.....|:.|.....|:||||.|||.|.
Worm   136 HTRSAIAPIFSTGKMKAMHETIHSKVDLFLEILKEKASSGQKWDIYDDFQGLTLDVIGKCAFAID 200

  Fly   196 CNSLRDEKAEFLHFGRRAL--LDSRH 219
            .|..||....|....|:.:  :|.||
Worm   201 SNCQRDRNDIFYVNARKFITNIDIRH 226

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	58/187 (31%)
cyp-25A6	NP_001360017.1	p450	37..>215	CDD:386267	54/177 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.720