Protein Alignment Cyp6a18 and cyp-25A4

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_497779.1
• Gene: cyp-25A4 / 183248
• WormBaseID: WBGene00007967
• Length: 501
• Species: Caenorhabditis elegans
• Alignment Length: 521
• Identity: 148/521 - (28%)
• Similarity: 240/521 - (46%)
• Gaps: 72/521 - (13%)

  Fly    14 LLAIVTYILHRKLTYFKRR---GIPYDKPHPLRGNME---------GYKKTRTVH-EIHQEYYNK 65
            ::..::|.:.|:...||.|   |||....|.|.||:.         ||..|...| .:|.:|
 Worm    13 IITFISYSIWRRHAIFKLRSSIGIPGPPVHWLWGNLNIIKDRVSRLGYNDTTQWHPTLHTKY--- 74

  Fly    66 YRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLD----- 125
                 .|..|.|...:....|.:.|..|:|.|:|||||:|:          |:..:|.::
 Worm    75 -----GPIFGLYCGTQLHITVSEEEDIKEIFIQNFSNFSDR----------MTPDIFGMNQLNQS 124

  Fly   126 ------GPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTV 184
                  ...|:..||.::..|::||||.|:.|:||..:.|:.|:.||.|.....|:.:.....::
 Worm   125 LLQNTYATGWKHTRSAIAPIFSTGKMKAMHETLVSKIDIFLEVLKEKSSSGQKWDIFENFQSLSL 189

  Fly   185 DVIGTCAFGIKCNSLRDEKAEFLHFGRR--ALLDSRHGNL--VSGLMRSYPNLARRLGLCRNTAQ 245
            |:||.|||.|..|..||....|....|:  ..:|.:...:  ||.::   |.|:.........:.
 Worm   190 DIIGKCAFAIDSNCQRDRTDLFYVQARKFVGAVDLKKSWILPVSLIL---PELSWLWRFLYKFSD 251

  Fly   246 IQEFYQRIVKETVTL--REKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFF 308
            :......:||..|.|  |.:.....||..|:|       |:.:.. |.:..:|..|::...|.|.
 Worm   252 LSAAELPLVKGLVDLYDRRRAGEGGNDSTDLL-------NLLIRR-ETIGKMTQREVIENCFAFL 308

  Fly   309 IAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHY 373
            |||::|:|:.|.|:.|.||:.|.:|.|:..|:.:..|  :....|:.|.::||||.|..|:||.|
 Worm   309 IAGYETTSTAMMFSAYLLAEYPIVQQKLYEEIKKTKE--NAGLNYDSIHNMKYLDCVYKESLRFY 371

  Fly   374 TIVPN-VDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRP 437
            ....: .:||......:.|.   :.....::.:....||.:|:.:..|:||:||||...|. |..
 Worm   372 PPTTHFTNRVCLNDMTIRGQ---IYPEDSTLKVQPYTIHRNPANWESPDEFQPERFENWEE-KSS 432

  Fly   438 SVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFS------PCSATPDPLTFDPHSAILLGI 496
            |:.|:|||.|||.|:|:||.:|:.:..:|.|:..|..|      |.....:.:.|.|.|.:.|.:
 Worm   433 SLKWIPFGVGPRYCVGMRFAEMEFKTTIAKLLDTFELSLVPGDPPMIPETNGVIFRPRSPVRLNL 497

  Fly   497 K 497
            |
 Worm   498 K 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	140/494 (28%)
cyp-25A4	NP_497779.1	p450	37..489	CDD:278495	137/486 (28%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R16884
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	13	12.910