Protein Alignment Cyp6a18 and cyp-25A1

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_497775.3
• Gene: cyp-25A1 / 183247
• WormBaseID: WBGene00007963
• Length: 502
• Species: Caenorhabditis elegans
• Alignment Length: 533
• Identity: 144/533 - (27%)
• Similarity: 247/533 - (46%)
• Gaps: 81/533 - (15%)

  Fly     7 LFQVAVALLAIVTYILHRKLTYFKRR---GIPYDKPHPLRGNME---------GY-KKTRTVHEI 58
            |..:.:::.....||:..:...||.|   |:...:||...||::         || ...|..:|:
 Worm     6 LSSLVISIFTFFIYIILARRERFKLREKIGLSGPEPHWFLGNLKQTAERKEKLGYDDANRWFNEL 70

  Fly    59 HQEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDK---GIYYNEKDDPMSAH 120
            |::|...:        |.|...:....:.:.:..|::.|||||||:|:   .||  |.:...::.
 Worm    71 HEQYGETF--------GIYYGSQMNIVISNEKDIKEVFIKNFSNFSDRSVPSIY--EANQLTASL 125

  Fly   121 LFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVD 185
            |.|.....|:..||.::..|::||||.|..|:.|..:.|:.::.||.|.....|:.|.....|:|
 Worm   126 LMNSYSSGWKHTRSAIAPIFSTGKMKAMQETINSKVDLFLDILREKASSGQKWDIYDDFQGLTLD 190

  Fly   186 VIGTCAFGIKCNSLRDEKAEFLHFGRRAL--LDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQE 248
            |||.|||.|..|..||....|....::.:  :|.||..:::..:.              ..::..
 Worm   191 VIGKCAFAIDSNCQRDRNDVFYVNAKKYISNIDIRHSKIIAASVL--------------LPELST 241

  Fly   249 FYQRIVKETVTLREKE--------NI-------KRNDFMDMLIGLKNQKNMTLENGEVVKGLTMD 298
            |::.:.|.| .|.:.|        |:       :.:|.:|:|..|.|:::      :..|.:|..
 Worm   242 FWKALYKYT-PLADAEIPLVEGLSNVYERRRGGEGSDSVDLLKLLLNRED------DKSKPMTKQ 299

  Fly   299 EIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLD 363
            |::...|.|.:||::|:|:.|.:..|.|:|.|::|.|:..|:.:..|  :...||:.|.::||||
 Worm   300 EVIENCFAFLLAGYETTSTAMTYCSYLLSKYPNVQQKLYEEIMEAKE--NGGLTYDSIHNMKYLD 362

  Fly   364 QVINETLRHY-TIVPNVDRVAAKRFVVPGN--PKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRP 425
            .|..||||.| .::..:.|:..:...:.|.  ||     |..|:.....:|.:|..:..|.||.|
 Worm   363 CVYKETLRFYPPVIHFIRRLCREDITIRGQFYPK-----GAIVVCLPHTVHRNPENWDSPEEFHP 422

  Fly   426 ERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPD------PL 484
            |||...|. |..|:.|:|||.|||.|:|:||.:|:.:..:..|:..|.........|      .:
 Worm   423 ERFENWEE-KSSSLKWIPFGVGPRYCVGMRFAEMEFKTTIVKLLDTFELKQFEGEADLIPDCNGV 486

  Fly   485 TFDPHSAILLGIK 497
            ...|:..:.|.:|
 Worm   487 IMRPNDPVRLHLK 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	137/499 (27%)
cyp-25A1	NP_497775.3	p450	37..496	CDD:278495	135/497 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	208	1.000	Domainoid score	I1665
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	213	1.000	Inparanoid score	I2346
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28638
OrthoDB	1	1.010	-	-		D264519at33208
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	1	1.000	-	-		mtm4722
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	1	1.100	-	-	O	PTHR24292
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.880