Protein Alignment Cyp6a18 and Cyp4a14

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_031848.1
• Gene: Cyp4a14 / 13119
• MGIID: 1096550
• Length: 507
• Species: Mus musculus
• Alignment Length: 423
• Identity: 104/423 - (24%)
• Similarity: 183/423 - (43%)
• Gaps: 62/423 - (14%)

  Fly   113 KDDPMSAHLFN------------LDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHE 165
            :.||.::.::.            |:|.:|...|..|:..|....:| .|..:::.:...|....|
Mouse   108 RSDPKASGIYQFFAPWIGYGLLLLNGKKWFQHRRMLTPAFHYDILK-PYVKIMADSVNIMLDKWE 171

  Fly   166 KV-SENSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRS 229
            |: .::..|::...|:..|:|.:..|||..:.:...||.::..   .:|:.|.  .||....:|:
Mouse   172 KLDGQDHPLEIFHCVSLMTLDTVMKCAFSYQGSVQLDENSKLY---TKAVEDL--NNLTFFRLRN 231

  Fly   230 --------YPNLARRLGLCRNTAQI-QEFYQRIVK----------ETVTLREKENIKRNDFMDML 275
                    | |::....|..:..|| .|....::|          |....|:|.::   ||:|:|
Mouse   232 AFYKYNIIY-NMSSDGRLSHHACQIAHEHTDGVIKMRKSQLQNEEELQKARKKRHL---DFLDIL 292

  Fly   276 IGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAEL 340
            :..:.:...:|.:         :::.|:...|...|.||::|.:.:..|.||.:|..|.:.|.|:
Mouse   293 LFARMEDRNSLSD---------EDLRAEVDTFMFEGHDTTASGISWIFYALATHPEHQQRCREEV 348

  Fly   341 GQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVII 405
            ..:|.. ....|::.:..:.|....|.|.||.|..|.:|.|..:.....|....  |..|.:..|
Mouse   349 QSILGD-GTSVTWDHLGQMPYTTMCIKEALRLYPPVISVSRELSSPVTFPDGRS--IPKGITATI 410

  Fly   406 PSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIK 470
            ....:||:|..:|.|..|.|.||:|:.|  ..|.|:|||..|.|||||.:|...:.::.:|:.:.
Mouse   411 SIYGLHHNPRFWPNPKVFDPSRFAPDSS--HHSHAYLPFSGGSRNCIGKQFAMNELKVAVALTLL 473

  Fly   471 NFTFSPCSATPDPLTFD-PHSAILLGIKGGIQL 502
            .|     ...|||.... |.:.::|..|.||.|
Mouse   474 RF-----ELLPDPTRIPVPIARLVLKSKNGIHL 501

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	101/419 (24%)
Cyp4a14	NP_031848.1	CYP4B-like	69..502	CDD:410771	104/423 (25%)