Protein Alignment Cyp6a18 and Cyp4a12b

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_758510.2
• Gene: Cyp4a12b / 13118
• MGIID: 3611747
• Length: 508
• Species: Mus musculus
• Alignment Length: 551
• Identity: 139/551 - (25%)
• Similarity: 221/551 - (40%)
• Gaps: 112/551 - (20%)

  Fly     1 MQLTYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEI-----HQ 60
            :.|...||:.|       ...|||:......:..|....|.|.|           |:|     .|
Mouse    25 LSLLLLLFKTA-------QLYLHRQWLLSSTQQFPSPPSHWLFG-----------HKILKDQDLQ 71

  Fly    61 EYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAH----- 120
            :...:.:|..:....:....|....|.|.:..|.||               .:.|| .||
Mouse    72 DILTRIKNFPSACPQWLWGSKVRIQVYDPDYMKLIL---------------GRSDP-KAHGSYRF 120

  Fly   121 --------LFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMA----VMHEK----VSE 169
                    |..|||..|...|..|:..|        :..::....|.||    ||.:|    |.:
Mouse   121 LAPWIGRGLLLLDGQTWFQHRRMLTPAF--------HYDILKPYTEIMADSVHVMLDKWEQIVGQ 177

  Fly   170 NSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEF----------LHFGRRALLDSRHGNLVS 224
            :|.|::...:...|:|.|..|||..:.:...|.|.:.          |.|.|  :.:..|.|.:.
Mouse   178 DSTLEIFQHITLMTLDTIMKCAFSHEGSVQLDRKYKSYIQAVEDLNNLFFLR--VRNIFHQNDII 240

  Fly   225 GLMRSYPNLARRLGLCR----NTAQIQEFYQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMT 285
            ..:.|...||.  ..|:    :|.|:.:..:..:::...|.:.:..:|.||:|:|:..:
Mouse   241 YRVSSNGCLAN--SACQLAHDHTDQVIKSRRSQLQDEEELEKLKKKRRLDFLDILLFAR------ 297

  Fly   286 LENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQK 350
            :|||   |.|:..::.|:...|...|.||::|.:.:..|.||.||..|.:.|.|: |.|......
Mouse   298 MENG---KSLSDKDLRAEVDTFMFEGHDTTASGISWIFYALATNPEHQQRCRKEI-QSLLGDGAS 358

  Fly   351 FTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGN---PKFVIEAGQSVIIPSSAIHH 412
            .|:..:..:.|....|.|.||.|..||:|.|..:.....|..   ||     |..|::....:||
Mouse   359 ITWNDLDKMPYTTMCIKEALRIYPPVPSVSRELSSPVTFPDGRSLPK-----GIHVMLSFYGLHH 418

  Fly   413 DPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPC 477
            :|:::|.|..|.|.||:|..|  |.|.::|||..|.|||||.:|...:.::.:|:.:..|
Mouse   419 NPTVWPNPEVFDPSRFAPGSS--RHSHSFLPFSGGARNCIGKQFAMNELKVAVALTLLRF----- 476

  Fly   478 SATPDPLTFD-PHSAILLGIKGGIQLKVEAI 507
            ...|||.... |...|:|..|.||.|.::.:
Mouse   477 ELLPDPTRVPIPIPRIVLKSKNGIHLHLKKL 507

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	131/509 (26%)
Cyp4a12b	NP_758510.2	CYP4B-like	70..503	CDD:410771	125/482 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900