Protein Alignment Cyp6a18 and Cyp4a10

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_034141.3
• Gene: Cyp4a10 / 13117
• MGIID: 88611
• Length: 509
• Species: Mus musculus
• Alignment Length: 570
• Identity: 138/570 - (24%)
• Similarity: 234/570 - (41%)
• Gaps: 141/570 - (24%)

  Fly     3 LTYFLFQVA------VALLAIVTYILHRK--LTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIH 59
            |:.|| |||      :.|:..|.:.|||:  |..|::      .|.|......|::|.:...|:
Mouse    15 LSGFL-QVASVLGLLLLLVKAVQFYLHRQWLLKAFQQ------FPSPPFHWFFGHEKFKGDQEL- 71

  Fly    60 QEYYNKYRNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDP-------- 116
            ||..:...|..:.|..::...|....|.|.:..|.||               .:.||
Mouse    72 QEIVSCIENFPSAFPRWFWGSKAYLTVYDPDYMKVIL---------------GRSDPKANGAYRL 121

  Fly   117 ----MSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK----VSENSIL 173
                :...|..|:|..|...|..|:..|....:|   |.|.::|:. :.:|.:|    ..::|.:
Mouse   122 LAPWIGYGLLLLNGQPWFQHRRMLTPAFHYDILK---PYVKNMADS-IRLMLDKWERLADQDSSI 182

  Fly   174 DVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNL-VSGLMRSYPNLARRL 237
            ::...::..|:|.:..|||                        |..|:: |.|..|:|   .:.:
Mouse   183 EIFQHISLMTLDTVMKCAF------------------------SHKGSVQVDGNYRTY---LQAI 220

  Fly   238 GLCRNT--AQIQE-FYQ-----------RIVKE-----------TVTLR--------EKENIK-- 267
            |...|.  ::::. |:|           |:.|:           .:.||        |.|.||
Mouse   221 GDLNNLFHSRVRNIFHQNDTIYKLSSNGRLAKQACQLAHDHTDGVIKLRKDQLQDEGELEKIKKK 285

  Fly   268 -RNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPS 331
             |.||:|:|:..:      :|||:   .::..::.|:...|...|.||::|.:.:..|.||.:|.
Mouse   286 RRLDFLDILLFAR------MENGD---SMSDKDLRAEVDTFMFEGHDTTASGVSWIFYALATHPD 341

  Fly   332 IQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGN---P 393
            .|.:.|.|: |.|.......|::.:..:.|....|.|.||.|..||.:.|..:.....|..   |
Mouse   342 HQQRCREEV-QSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVTFPDGRSLP 405

  Fly   394 KFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQ 458
            |     |..|.:....:||:|.::|.|..|.|.||:|:  :.|.|.::|||..|.|||||.:|..
Mouse   406 K-----GVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPRHSHSFLPFSGGARNCIGKQFAM 463

  Fly   459 MQARIGLAMLIKNFTFSPCSATPDPLTFD-PHSAILLGIKGGIQLKVEAI 507
            .:.::.:|:.:..|     ...|||.... |.:.::|..|.||.|.::.:
Mouse   464 SELKVIVALTLLRF-----ELLPDPTRVPMPLARLVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	125/522 (24%)
Cyp4a10	NP_034141.3	p450	52..503	CDD:278495	124/519 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900