Protein Alignment Cyp6a18 and Cyp3a13

DIOPT Version :9

• Sequence 1: NP_001287562.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_031845.1
• Gene: Cyp3a13 / 13113
• MGIID: 88610
• Length: 503
• Species: Mus musculus
• Alignment Length: 520
• Identity: 160/520 - (30%)
• Similarity: 257/520 - (49%)
• Gaps: 64/520 - (12%)

  Fly     4 TYFLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEI--HQEYYNKY 66
            |:.|  :|.:|:.:..|..|.. ..||:.|||..||.|..|.:..|:|.....:|  |::|...:
Mouse    11 TWML--LATSLVLLYLYGTHSH-GIFKKLGIPGPKPLPFLGTILAYQKGFWECDIQCHKKYGKMW 72

  Fly    67 RNSKAPFVGFYLFQKPAAFVIDLELAKQILIKN-FSNFTD-----------KGIYYNEKDDPMSA 119
                    |.|..::|...:.|.::.|.:|:|. :|.||:           |.|..:|.:
Mouse    73 --------GLYDGRQPVLAITDPDIIKTVLVKECYSTFTNRRRFGPVGILKKAISISENE----- 124

  Fly   120 HLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTV 184
                    :|:.:|:.||.|||||::|.|:|.:....:..:..|.:.:.|.....::|:...:::
Mouse   125 --------EWKRIRALLSPTFTSGRLKEMFPIINQFTDVLVRNMRQGLGEGKPTSMKDIFGAYSM 181

  Fly   185 DVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRS---YPNLA---RRLGLCRNT 243
            |||...:||:..:||.:.:..|:...::.|    ..::...|..|   :|.|.   ..|.:....
Mouse   182 DVITATSFGVNIDSLNNPQDPFVEKIKKLL----KFDIFDPLFLSVTLFPFLTPVFDALNVSLFP 242

  Fly   244 AQIQEFYQRIVKETVTLREKENIK-RNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVF 307
            ..:..|:...|:.....|.||..| |.||:.::|..:|.|..     |..|.|:..|||||:.:|
Mouse   243 RDVISFFTTSVERMKENRMKEKEKQRVDFLQLMINSQNYKTK-----ESHKALSDVEIVAQSVIF 302

  Fly   308 FIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRH 372
            ..||::|:||.:.||||.||.:|.:|.|::.|:...| .:....||:.:..::|||.|:|||||.
Mouse   303 IFAGYETTSSALSFALYLLAIHPDVQKKLQDEIDAAL-PNKAPATYDTLLQMEYLDMVVNETLRL 366

  Fly   373 YTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRP 437
            |.|...::||......:.|   ..|..|..|:||:.|:|.||..:|||.||||||||.:......
Mouse   367 YPIAGRLERVCKTDVEING---LFIPKGTVVMIPTFALHKDPKYWPEPEEFRPERFSKKNQDSIN 428

  Fly   438 SVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPL------TFDPHSAILLGI 496
            ...:||||.|||||||:||..:..::.|..:::|||..||..|..||      ...|.:.:||.:
Mouse   429 PYMYLPFGSGPRNCIGMRFALINMKVALVRVLQNFTVQPCKETEIPLKLSKQGLLQPENPLLLKV 493

  Fly   497  496
            Mouse   494  493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_001287562.1	p450	38..504	CDD:278495	149/486 (31%)
Cyp3a13	NP_031845.1	p450	39..491	CDD:365848	148/485 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG0158
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000037
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100014
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X40
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.710