Protein Alignment Cyp6a18 and LOC1273546

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_001237478.4
• Gene: LOC1273546 / 1273546
• VectorBaseID: AGAMI1_006380
• Length: 494
• Species: Anopheles gambiae
• Alignment Length: 545
• Identity: 147/545 - (26%)
• Similarity: 246/545 - (45%)
• Gaps: 110/545 - (20%)

  Fly     6 FLFQVAVALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGN---MEGYKKTRTVHEIHQEYYNKYR 67
            ::..:|:.:| ::.::..|...|.....:|....:.|.||   :..| .|:...|...||:.:|.
Mosquito     4 YVLLIALCVL-VLRFVAFRYKVYRTVGHLPGPPVNFLLGNTLELVRY-DTQVFFEKLFEYFQRYG 66

  Fly    68 N-------SKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFN-- 123
            .       :|.    :.:|..|.    |:|   ||:..|  .|..|.:.|    |.:...|.|
Mosquito    67 TIVRLDMINKV----WIIFSSPH----DIE---QIISSN--EFNRKSMDY----DILQEWLGNGI 114

  Fly   124 -LD-GPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSE--NSILDVRDLVARFTV 184
             || |..|...|..|:..|   ..|.: .|.|.|.||...|:..|:.:  .:.:|:..:|..:|:
Mosquito   115 LLDYGNTWFSNRRALTGAF---HFKIL-DTYVPVFEEQADVLVRKLLDAGGATVDIFAMVKLYTL 175

  Fly   185 DVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTAQIQEF 249
            |||...:.|::|.: :.|.::::    ||:.|..|    ....|.|           |.....::
Mosquito   176 DVILETSMGVRCRA-QLEDSDYV----RAVTDLTH----ITFWRMY-----------NAMGFSDW 220

  Fly   250 YQRIVKETVTLREKENIKRNDFMDMLIGLKNQKNMTL-----------ENGEV----------VK 293
            ..|:.|...|.|:...|.| :|...:|   .|:...|           |.|.:          :.
Mosquito   221 TFRLTKHYQTYRKSLQINR-EFTTSVI---TQRRAELLAAGISDTTRPEKGRLSLLDILLRSDIT 281

  Fly   294 GLTM--DEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHD-QKFTYEC 355
            |.|.  :|:.:|...|..||.||:||.:.|.||..||:|.:|.:|..|:  |:|..| :..|.:.
Mosquito   282 GRTFSDEEVYSQVNNFMFAGHDTTSSAITFILYACAKHPEVQQRVYEEI--VVELPDGEPVTQQR 344

  Fly   356 IKDLKYLDQVINETLRHYTIVP----NVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSI 416
            :.:||||:|||.|:||.:..||    ::|....:     |..:  :|.|.::::.:..:||:|..
Mosquito   345 VNNLKYLEQVIKESLRMFPPVPYYSRHIDHDTTQ-----GGVR--LEKGSTIVLGTYMLHHNPEY 402

  Fly   417 YPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSA-T 480
            :|||::||||||:..|:.:.| .|::||..|.|||||.:|...:.:..|..:::.     |.. .
Mosquito   403 FPEPDQFRPERFADGETKRNP-FAYIPFSAGSRNCIGQKFALNELKTALVKILRQ-----CKVEL 461

  Fly   481 PDPLTFDPHSAILLGIK--GGIQLK 503
            ||| .|.|...:.|.:|  .|:||:
Mosquito   462 PDP-DFVPKMKMELVLKPVNGMQLR 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	130/466 (28%)
LOC1273546	XP_001237478.4	None