Protein Alignment Cyp6a18 and LOC1273542

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_312527.5
• Gene: LOC1273542 / 1273542
• VectorBaseID: AGAMI1_002993
• Length: 503
• Species: Anopheles gambiae
• Alignment Length: 546
• Identity: 129/546 - (23%)
• Similarity: 239/546 - (43%)
• Gaps: 112/546 - (20%)

  Fly     9 QVAVALLAI---VTYILHRKLTYFKRRGIPYDKPHPLRG------NMEGYKKTRTVHEIHQEYYN 64
            |:.:|||.:   :.|:|.|:...:.|. ||...|.|:.|      |::.......|.::.:.|.|
Mosquito     6 QIGLALLVVILTINYLLVRQNIKYGRH-IPGPVPLPIVGCFYLYINLKPEDIIDFVSDLRKRYGN 69

  Fly    65 KYRNSKAPFVGFYLFQKPAAFVIDLE-----LAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNL 124
            .:|        .::..:.|.|..:::     |:.|.||:       |...|......:...|...
Mosquito    70 LFR--------VWIGNRLALFCTNVKYNETVLSSQKLIR-------KSELYKFLIPWLGDGLLLS 119

  Fly   125 DGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVS----------ENSILDVRDLV 179
            .|.:|...|..|:..|.           ..:.::|:.|.|::.|          ...::::...|
Mosquito   120 TGQKWFSKRKILTPAFH-----------FKILDQFIEVFHKQSSILADRLRPEANGQLVNIYPFV 173

  Fly   180 ARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRLGLCRNTA 244
            ....:|:|...|.|...|:..|..:.::    :|:.:.   :||  |...:..:.:|:....|.:
Mosquito   174 TLAALDIICETAMGTSINAQTDADSAYV----KAITEL---SLV--LTGRFVKVWQRVDFLFNLS 229

  Fly   245 QIQEFYQRIVK-------ETVTLREKENI-------------------KRNDFMDMLIGLKNQKN 283
            ..:....||:|       :.:..|.:|.:                   :|..|:|:|:      .
Mosquito   230 PDKRRQDRIIKVLHDFTTKIIQSRRRELMEQGGGGTVEDEDMADLGTKRRMAFLDVLL------Q 288

  Fly   284 MTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVL-EQH 347
            .|::.    :.||..||..:...|...|.||::..:.|.|..||::|.:|::|..|:..:: ...
Mosquito   289 ATIDG----RPLTDREIQEEVDTFMFEGHDTTTIAISFTLLLLARHPEVQERVYREVAAIVGNDP 349

  Fly   348 DQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFV--VPGNPKFVIEAGQSVIIPSSAI 410
            ....|:..::|:|||:.||.|:||.|..||    :.|:||.  |....|.|.| |.:..|....:
Mosquito   350 ATPATHRNLQDMKYLELVIKESLRLYPPVP----IIARRFTENVELGGKIVPE-GSNFNIGIMHM 409

  Fly   411 HHDPSIYPEPNEFRPERFSPEESAKRPS-VAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNFTF 474
            |.||:::|:|..|.||||:|:.:.::.| .|::||..|||||||.:|..::.:..::.:|::|..
Mosquito   410 HRDPTLFPDPERFDPERFAPDRTMEQSSPYAYVPFSAGPRNCIGQKFAMLELKSTVSKVIRHFKL 474

  Fly   475 SPCSATPDP-----LTFDPHSAILLG 495
            :  :|.|:|     ||..|...:.:|
Mosquito   475 T--AAGPEPKLTMQLTLKPRDGLYIG 498

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	111/476 (23%)
LOC1273542	XP_312527.5	None