Protein Alignment Cyp6a18 and LOC1273099

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_312046.4
• Gene: LOC1273099 / 1273099
• VectorBaseID: AGAMI1_003432
• Length: 500
• Species: Anopheles gambiae
• Alignment Length: 516
• Identity: 173/516 - (33%)
• Similarity: 286/516 - (55%)
• Gaps: 32/516 - (6%)

  Fly     4 TYFLFQVAVALLAI-VTYILHRKLTYFKRRGIPYDK-PHPLRGNMEGYKKTRTVHEIHQEYYNKY 66
            |:.|....:.|..: |...|.|:.|:::|.|||..: ||||.||:.|.........:.|..|.::
Mosquito     5 TWVLVLCTIVLTGVAVRMFLRRRQTFWQRHGIPAARHPHPLYGNVGGLVTKHHTATVLQRLYREF 69

  Fly    67 RNSKAPFVGFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAH-LFNLDGPQWR 130
            |..|.|..||.|:..|...|:|.:|.:::|:.:|:.|.::|:|.:...:|:|:. ||::.|.:|.
Mosquito    70 RERKLPAGGFNLYFSPVLLVVDRQLIERVLVNDFAQFQNRGLYASATVNPLSSETLFSVAGERWH 134

  Fly   131 LLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGIK 195
            .:|.:|.....|..::.|:.|...:|:..:..:..: |....|:..||:||:..||||:|||||.
Mosquito   135 RMRQQLRPALGSSSVRTMFATTARIAQTLVVYIGAQ-SRRRDLEWTDLMARYATDVIGSCAFGID 198

  Fly   196 CNSLRDEKAEFLHFGRRALLDS--RHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKETV 258
            |.::||..:||...|.||...|  |...|..|.  :...:|..:.||.:...:::|:.::.:.||
Mosquito   199 CRTIRDPGSEFRAMGHRAFRCSLRRMWKLRFGY--ACRRVADAMRLCVSEPSVEQFFLQLCQSTV 261

  Fly   259 TLREKENIKRNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFAL 323
            ..||...:.:.||:..|:.:|       .||    .|.|.::..|.:.||||||:||:|.:.|.|
Mosquito   262 LHRESYQVVKRDFLQQLLEMK-------ANG----ALDMRQVAGQCYSFFIAGFETSASLLSFCL 315

  Fly   324 YELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFV 388
            |||||:.::||::|..:...|::.|.:.:|:.:..|.|||||:.||||.|..|..:.|||:..:.
Mosquito   316 YELAKHGAVQDRLRGSIVAALDETDGQLSYDMVMALGYLDQVVKETLRMYPPVDFLFRVASNDYP 380

  Fly   389 VPGNPKF-VIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEE-----SAKRPSVAWLPFGEG 447
            :.|   | .|..|..:::|..|:|.||:.||:|:.:.|:||:...     |..||  .::|||.|
Mosquito   381 IDG---FGTIPQGTLLVVPVHALHRDPAYYPQPDVYNPDRFAASSKLSGASKNRP--PFMPFGLG 440

  Fly   448 PRNCIGLRFGQMQARIGLAMLIKNFTFS-PCSATPDPLTFDPHSAILLGIKGGIQLKVEAI 507
            ||:|||..||.|..::||..::::|.|: ....||:.:||.|.| ::|....|:.|.||.:
Mosquito   441 PRHCIGDTFGLMLVKVGLVAMVRSFRFTLDVDRTPENVTFKPRS-LVLAAGSGMYLNVERV 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	148/439 (34%)
LOC1273099	XP_312046.4	CYP6-like	72..494	CDD:410679	149/441 (34%)