Protein Alignment Cyp6a18 and Cyp4v3

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_598730.1
• Gene: Cyp4v3 / 102294
• MGIID: 2142763
• Length: 525
• Species: Mus musculus
• Alignment Length: 505
• Identity: 141/505 - (27%)
• Similarity: 212/505 - (41%)
• Gaps: 86/505 - (17%)

  Fly    11 AVALLAIVTYILHRKLTYFKRRGIP-YDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFV 74
            |..|::|...::.....:.:.|.|| ..:.:||.|:.. |.|........|..|........|.:
Mouse    27 ATILISIFPMLVSYARKWQQMRSIPSVARAYPLVGHAL-YMKPNNAEFFQQLIYYTEEFRHLPII 90

  Fly    75 GFYLFQKPAAFVIDLELAKQILIKNFSNFTDKGIYYNEKDDPMSAHLFNLDGPQWRLLRSKLSST 139
            ..::...|...:...|..:.||..  |...||...|......:...|....|.:||..|..|:.|
Mouse    91 KLWIGPVPLVALYKAENVEVILTS--SKQIDKSFLYKFLQPWLGLGLLTSTGSKWRTRRKMLTPT 153

  Fly   140 FTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDV------IGTCAFGIKCNS 198
            |.           .::.|.|:.||:|:.   :|| |..|......:.      |..||..|.|
Mouse   154 FH-----------FTILENFLDVMNEQA---NIL-VNKLEKHVNQEAFNCFFYITLCALDIIC-- 201

  Fly   199 LRDEKAEFLHFGRRALLDSRHGNLVSGLMRSYPNLARRL----------------------GL-C 240
               |.|...:.|.::..||.:   |..:.|....:.||:                      || |
Mouse   202 ---ETAMGKNIGAQSNNDSEY---VRTVYRMSDMIYRRMKMPWLWFDLWYLVFKEGRDHKRGLKC 260

  Fly   241 RNTAQIQEFYQRIVKETVTLREKE-------------NIKRNDFMDMLIGLKNQKNMTLENGEVV 292
            .:|     |...::.|.|..|:.|             ..||..|:|:|:      ::|.|.|
Mouse   261 LHT-----FTNNVIAERVKERKAEEDWTGAGRGPIPSKNKRKAFLDLLL------SVTDEEG--- 311

  Fly   293 KGLTMDEIVAQAFVFFIAGFDTSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIK 357
            ..|:.::|..:...|...|.||:::.:.::||.|..||.:|.||..||.:|..:..:..|.|.:|
Mouse   312 NRLSQEDIREEVDTFMFEGHDTTAAAINWSLYLLGTNPEVQRKVDQELDEVFGRSHRPVTLEDLK 376

  Fly   358 DLKYLDQVINETLRHYTIVPNVDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNE 422
            .|||||.||.||||.:..||...|..::...|.|   :.:..|...||...|:|.||..:|:|.|
Mouse   377 KLKYLDCVIKETLRVFPSVPLFARSLSEDCEVGG---YKVTKGTEAIIIPYALHRDPRYFPDPEE 438

  Fly   423 FRPERFSPEESAKRPSVAWLPFGEGPRNCIGLRFGQMQARIGLAMLIKNF 472
            ||||||.||.|..|...|::||..|||||||.:|..|:.:..||.:::.|
Mouse   439 FRPERFFPENSQGRHPYAYVPFSAGPRNCIGQKFAVMEEKTILACILRQF 488

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	128/445 (29%)
Cyp4v3	NP_598730.1	CYP4V	76..515	CDD:410773	130/455 (29%)