Protein Alignment Cyp6a18 and LOC100487846

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_017950484.2
• Gene: LOC100487846 / 100487846
• XenbaseID: XB-GENE-29078943
• Length: 512
• Species: Xenopus tropicalis
• Alignment Length: 518
• Identity: 156/518 - (30%)
• Similarity: 256/518 - (49%)
• Gaps: 60/518 - (11%)

  Fly    12 VALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFVGF 76
            |.||.::.|........|||.|||...|.|..|...|.:  ..:.|...:.:.||.|    ..||
 Frog    16 VLLLTLLAYYAIWPYRLFKRYGIPGPTPIPFIGTFLGNR--HGLMEFDMKCFKKYGN----VWGF 74

  Fly    77 YLFQKPAAFVIDLELAKQILIKN-FSNFTDKGIYYNEKDDPMSAHLFNLDGP-----------QW 129
            |...:|...::|..:.|.|::|. ::|||      |.:|       |.|.||           ||
 Frog    75 YDGPQPVLAILDPVIIKSIMVKECYTNFT------NRRD-------FGLSGPLKSSVLMSKDEQW 126

  Fly   130 RLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGI 194
            :.:|:.||.||||||:|.|:|.:....|..:..:|:|:.....||::.:...:::|.|.:.:|.:
 Frog   127 KRIRTVLSPTFTSGKLKQMFPLMKHYGELLVKNIHKKIDNKEPLDMKSIFGSYSMDTILSTSFSV 191

  Fly   195 KCNSLRDEKAEFLHFGRRALLDS--RHGNLVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKET 257
            ..:|:.:....|:...|.....|  :...|::.|.........::..|..:::..:|::..|...
 Frog   192 NVDSMNNPNDPFVTNARNLFTFSFFKPLFLITILCPFLVPFLDKMNFCFLSSKFLKFFKDAVASI 256

  Fly   258 VTLREK-ENIKRNDFMDMLIGLKNQKNMTLENGEVV--------KGLTMDEIVAQAFVFFIAGFD 313
            ...|:| .::.|.||:.:::..::.:      ||.|        |.|:..||:||:.:|.:||::
 Frog   257 KKKRQKGAHMDRVDFLQLMVDAQSNE------GESVPEEEKHRHKELSDTEILAQSLIFIMAGYE 315

  Fly   314 TSSSTMGFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPN 378
            |:|:|:.|..|.:|:.|.:|.|:..|:..:|...... ||:.:..::|:|.|||||||.......
 Frog   316 TTSTTLMFLTYNIARYPDVQRKLEEEINTLLPNKAPP-TYDALMKMEYMDMVINETLRLLPPAIR 379

  Fly   379 VDRVAAKRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLP 443
            :|||..|...:.|   ..|.||..:::|..|:|.:|.|:|||.||:|||||.|....:....:||
 Frog   380 IDRVCKKTMEING---VTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLP 441

  Fly   444 FGEGPRNCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPL------TFDPHSAILLGI--KG 498
            ||.|||||||:||..:..::.|.:|::||....|..||.||      ...|...|:|.:  ||
 Frog   442 FGVGPRNCIGMRFALVNIKLALTILLQNFKLETCKDTPVPLKVCTRGNLKPTKPIILNLVPKG 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	138/460 (30%)
LOC100487846	XP_017950484.2	cytochrome_P450	67..498	CDD:477761	138/457 (30%)