Protein Alignment Cyp6a18 and Cyp4a32

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: NP_001093651.1
• Gene: Cyp4a32 / 100040843
• MGIID: 3717148
• Length: 509
• Species: Mus musculus
• Alignment Length: 578
• Identity: 140/578 - (24%)
• Similarity: 234/578 - (40%)
• Gaps: 157/578 - (27%)

  Fly     3 LTYFLFQVA------VALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQ- 60
            |:.|| |||      :.|:..|.:.||||......:..|....|...|: |.:|..:.:.|:..
Mouse    15 LSGFL-QVASVLGLLLLLVKAVQFYLHRKWLLKALQQFPSPPFHWFFGH-EQFKGEQELKEVVSC 77

  Fly    61 -EYYNKYRNSKAPFVGFYLFQKPAAF------------VIDLELAKQILIKNFSNFTDKGIY--- 109
             |::                  |:||            |.|.:..|.||.:  |:....|||
Mouse    78 IEHF------------------PSAFPCWFWGSNAYLTVYDPDYMKVILGR--SDPKANGIYRLL 122

  Fly   110 -----YNEKDDPMSAHLFNLDGPQWRLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEK--- 166
                 |.         |..|:|..|...|..|:..|....:|   |.|.::|:. :.:|.:|
Mouse   123 APWIGYG---------LLLLNGQPWFQHRRMLTPAFHYDILK---PYVKNMADS-IRLMLDKWER 174

  Fly   167 -VSENSILDVRDLVARFTVDVIGTCAFGIKCNSLRDEKAEFLHFGRRALLDSRHGNL-VSGLMRS 229
             ..::|.:::...::..|:|.:..|||                        |..|:: |.|   :
Mouse   175 LAGQDSSIEIFQHISLMTLDTVMKCAF------------------------SHKGSVQVDG---N 212

  Fly   230 YPNLARRLGLCRNT--AQIQE-FYQ-----------RIVKETVTLR------------------- 261
            |....:.:|...|.  ::::. |:|           |:.|:...|.
Mouse   213 YKTYLQAIGDLNNLFHSRVRNIFHQNDTIYRLSSNGRLAKQACQLAHDHTDGVIKMRKDQLQDEG 277

  Fly   262 EKENIK---RNDFMDMLIGLKNQKNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTMGFAL 323
            |.||||   |.||:|:|:..:      :|||:   .::..::.|:...|...|.||::|.:.:..
Mouse   278 ELENIKKKRRLDFLDILLFAR------MENGD---SMSDKDLRAEVDTFMFEGHDTTASGVSWIF 333

  Fly   324 YELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAAKRFV 388
            |.||.:|..|.:.|.|: |.|.......|::.:..:.|....|.|.||.|..||.:.|..:....
Mouse   334 YALATHPEHQQRCREEV-QSLLGDGSSITWDHLDQIPYTTMCIKEALRLYPPVPGIVRELSTSVT 397

  Fly   389 VPGN---PKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPRN 450
            .|..   ||     |..|.:....:||:|.::|.|..|.|.||:|:  :.|.|.::|||..|.||
Mouse   398 FPDGRSLPK-----GVQVTLSIYGLHHNPKVWPNPEVFDPSRFAPD--SPRHSHSFLPFSGGARN 455

  Fly   451 CIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLTF-DPHSAILLGIKGGIQLKVEAI 507
            |||.:|...:.::.:|:.:.:|     ...|||... :|.:.|:|..|.||.|.::.:
Mouse   456 CIGKQFAMSELKVIVALTLLHF-----ELLPDPTRVPEPLARIVLKSKNGIYLHLKKL 508

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	118/494 (24%)
Cyp4a32	NP_001093651.1	CYP4B-like	71..504	CDD:410771	122/514 (24%)