Protein Alignment Cyp6a18 and cyp3a5

DIOPT Version :10

• Sequence 1: NP_651563.1
• Gene: Cyp6a18 / 43304
• FlyBaseID: FBgn0039519
• Length: 507
• Species: Drosophila melanogaster
• Sequence 2: XP_012819594.1
• Gene: cyp3a5 / 100037874
• XenbaseID: XB-GENE-5821575
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 508
• Identity: 155/508 - (30%)
• Similarity: 254/508 - (50%)
• Gaps: 46/508 - (9%)

  Fly    12 VALLAIVTYILHRKLTYFKRRGIPYDKPHPLRGNMEGYKKTRTVHEIHQEYYNKYRNSKAPFVGF 76
            |.||.::.|........|||.|||...|.|..|...|.:  ..:.|...|.:.||    ....|.
 Frog    16 VLLLTLLAYYAIWPYKLFKRYGIPGPTPIPFIGTFLGNR--HGLMEFDMECFKKY----GKVWGI 74

  Fly    77 YLFQKPAAFVIDLELAKQILIKN-FSNFTDKGIYYNEKDDPMSAHLFNLDGP-----------QW 129
            |..|||...::|..:.|.|::|. ::|||      |.:|       |.|.||           ||
 Frog    75 YEGQKPLLAIVDPVIIKSIMVKECYTNFT------NRRD-------FGLSGPLKSSVLISKDEQW 126

  Fly   130 RLLRSKLSSTFTSGKMKFMYPTVVSVAEEFMAVMHEKVSENSILDVRDLVARFTVDVIGTCAFGI 194
            :.:|:.||.||||||:|.|:|.:....|..:..:|:|::....||::.:...:::|::.:.:|.:
 Frog   127 KRIRTVLSPTFTSGKLKQMFPLMNHYGELLVKNIHKKINNKEPLDMKHIFGSYSMDIVLSTSFSV 191

  Fly   195 KCNSLRDEKAEFLHFGRRALLDSRHGN--LVSGLMRSYPNLARRLGLCRNTAQIQEFYQRIVKET 257
            ..:|:.:....|:...|.....|....  |:|.|......|..::..|..:.:|..|::..|...
 Frog   192 NVDSMNNPNDPFVTNARNLFTFSFFNPLFLISILCPFLVPLLDKMNFCFLSLKILNFFKDAVASI 256

  Fly   258 VTLREK-ENIKRNDFMDMLIGLKNQ--KNMTLENGEVVKGLTMDEIVAQAFVFFIAGFDTSSSTM 319
            ...|:| .:..|.||:.:::..::.  |::..|.....|.|:..||:||:.:|.:||::|:|:|:
 Frog   257 KKKRQKGTHEDRVDFLQLMVDAQSNEGKSVPEEEKHGYKELSDTEILAQSLIFIMAGYETTSTTL 321

  Fly   320 GFALYELAKNPSIQDKVRAELGQVLEQHDQKFTYECIKDLKYLDQVINETLRHYTIVPNVDRVAA 384
            .|..|.:|.:|.:|.|:..|:..:|...... ||:.:..::|:|.||||:||.:.....:|||..
 Frog   322 MFLAYNIATHPDVQRKLEEEIDALLPNKAPP-TYDALMKMEYMDMVINESLRMFPPAIRIDRVCK 385

  Fly   385 KRFVVPGNPKFVIEAGQSVIIPSSAIHHDPSIYPEPNEFRPERFSPEESAKRPSVAWLPFGEGPR 449
            |...:.|   ..|.||..:::|..|:|.:|.|:|||.||:|||||.|....:....:||||.|||
 Frog   386 KTMEING---VTIPAGVVIVVPLFALHLNPEIWPEPEEFQPERFSKENQKNQDPYNFLPFGVGPR 447

  Fly   450 NCIGLRFGQMQARIGLAMLIKNFTFSPCSATPDPLT------FDPHSAILLGI 496
            ||||:||..:..::.|.:|::||....|..||.||.      ..|...|:|.:
 Frog   448 NCIGMRFALVNMKVALTILLQNFRLETCKDTPVPLKICTKGYLKPTKPIILNL 500

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cyp6a18	NP_651563.1	CYP6-like	70..500	CDD:410679	137/450 (30%)
cyp3a5	XP_012819594.1	cytochrome_P450	67..498	CDD:477761	138/451 (31%)