Protein Alignment CG13978 and GPI13

DIOPT Version :10

• Sequence 1: NP_651562.2
• Gene: CG13978 / 43303
• FlyBaseID: FBgn0039518
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_013069.1
• Gene: GPI13 / 850628
• SGDID: S000003954
• Length: 1017
• Species: Saccharomyces cerevisiae
• Alignment Length: 989
• Identity: 171/989 - (17%)
• Similarity: 324/989 - (32%)
• Gaps: 353/989 - (35%)

  Fly     4 LQALVVHILLMGAILNTYFQHTLLPNLVPQKTMRELGLEPPA-DRLVVFVTDGLR---------- 57
            ||.:.:.....|.:|:.:    :|.|:..|....:|   ||. ::.|:.|.|.||
Yeast    45 LQFISIAFFTRGFLLSRH----VLDNISSQNETSKL---PPRFNKAVILVIDALRFDFAIPVNES 102

  Fly    58 AATFLANNGSDVPDLKDIYRQ--------------------QGRIGISRTCAPTMTRPGHIAIFA 102
            .:.:..|..:::..|.|.:..                    |...|::....||....|  :.|.
Yeast   103 HSNYNLNYHNNILSLYDSFASDKDASSLLLKFIADPPTTTLQRLKGLTTGSLPTFIDAG--SNFD 165

  Fly   103 G--FHEDPAASLMHLCYNPGDFDTVFNRSRNMIG---WA---HSYIVGYFVKLSHGGAPLRFDSY 159
            |  ..||.....:||.          |::....|   |.   |.:       ||:...||.
Yeast   166 GTVIEEDNFLKQLHLA----------NKTVKFAGDDTWMALFHPF-------LSNDSFPLE---- 209

  Fly   160 MERDLPEKLTCDKWAFDKVEN-----FLRNVDNVREWRNYKPAVFFVYLADMDIAAHRFKP---- 215
                     :.:.|..|.|:|     |..::...:||     .|...::..:|...|::.|
Yeast   210 ---------SLNVWDLDTVDNGVMDYFHDHLQQDKEW-----DVMIGHMLGIDHVGHKYGPDHFT 260

  Fly   216 LSKKFFAKLQYTQRGIRNTYELFERVFNDSRTAYLMTSDHGMNNEGAHGSGSPLEVETPLFMWGA 280
            :.:|.....|:....:::.         |..|..::..||||::.|.||..|..|:|:.||::..
Yeast   261 MREKQIQVDQFIDWILKSI---------DDDTLLVILGDHGMDHTGNHGGDSIDELESTLFLYSK 316

  Fly   281 GVKRDEIDAEANFPEKPNIS-------QVDQTQLAPLMSSLIGLPPPKNNLALMPVGYLNVSDE- 337
            ......:...:|:    ||.       .|.|..|...::.|:|.|.|.|||. .|:..:..:|.
Yeast   317 KPDMWRLKETSNY----NIDNLGHDYRSVRQIDLVSSLALLMGQPIPFNNLG-WPIDEIARNDRE 376

  Fly   338 -YQAVALHLNVLQLLSQA-EILIGRHE------KAI-----------FYKWLPKFKELHIGVIDQ 383
             .|.|...::.|||.... :|..|..|      |.|           |.|...|::::.:...::
Yeast   377 WSQFVNSAISQLQLYKDTMQIHHGNDEILEPLAKNISNTPPTSDPEKFVKLGHKYQKVFLQTCEE 441

  Fly   384 YAAQFDILKSEGNLTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIWFYCLLLQLTRL 448
            ..|:||                           ||:        :|..::.:.....||:.:|:|
Yeast   442 LWAKFD---------------------------YYS--------IATGITLLATSLVLLISITKL 471

  Fly   449 SKKEKMQRRGFMTVSTLILAMIGILLIAMMELQKVPHIAAFYLILPV---GMLIMAQAERPVRGY 510
                                 |..:::..|..:.||.|....|:..:   |:..:.|....|..:
Yeast   472 ---------------------IPSIVVNQMVPEFVPGIIIMVLVTNLCFHGIFYVYQQPSFVDQF 515

  Fly   511 WIFHPLWNFGFILVPAVLIMSMTFIIRHLWVLYGISVLLNNRRALRKPSIKLFIWLSLALIVTAI 575
            |        |.:|..|:            .::.|..:.:.:|..        |||:::.|..|
Yeast   516 W--------GTLLATAI------------GIIIGCYITIFDRYN--------FIWIAMRLGET-- 550

  Fly   576 LFMEQRTIKGLKTIPVKDYHVLYVSMVLAIIRPLILGHRHDPRVWTFNSLTL--------VVGAF 632
                           :.||. ..::::..||..|:         :|.||.|:        ::..|
Yeast   551 ---------------LADYW-SRIAVMFMIIHALL---------FTSNSFTIWEDRIVAFLLSTF 590

  Fly   633 G---VYQYKFYESVSSYVYVVTW--------------SFLFFAFLSIVYFAKSLPEARKRLELIT 680
            |   :|::.|.....|...::|.              |.....:|.:..||:.|......:.:|.
Yeast   591 GMLTLYEFVFLPKRQSTTALLTATISEKEGTTSGVNPSTANSNYLPLTRFARLLGGYHSAVLIIF 655

  Fly   681 INMITVLSLLTNSWGCLNFQIAITEFIFGLQIYEETKETKEIEDAKDEHTSLQNLKGFYRYGYMI 745
            ..:.:::::.....|    :..|..|                        :.||...::..|...
Yeast   656 TRLASMITICREEQG----EYCIPTF------------------------NNQNNSSWWVLGLCF 692

  Fly   746 LLYFYVSFFLAGHWISSFLFKPTTARLFYPHFSLYIAGSLVLLKIFIPSVIFICALY-------- 802
            |:.|.:...:.|               :|...|.|.|.:.:.:.:|:..::.:..:|
Yeast   693 LMIFILPACITG---------------YYNLTSSYQAAAPIWINVFLKGILGLNFVYWSLTSLEN 742

  Fly   803 ----AMVPFVRKNARSILISIFMISNAMGLYQYYFIRNRGSWRKIRMFLDQILLTHAVNFMLLLG 863
                ..:||:|.      ::||..:.|..:..:..|.:...|                    |:|
Yeast   743 NSAVIAIPFLRD------VTIFKFTLARIIAGFSLIASNVGW--------------------LMG 781

  Fly   864 ISLAKIFLANTTME 877
            ....|:.:.||.::
Yeast   782 PLCIKLNIHNTDVK 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	69/340 (20%)
		PigN	413..839	CDD:461508	70/465 (15%)
GPI13	NP_013069.1	GPI_EPT_3	77..367	CDD:293747	69/340 (20%)