DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13978 and AT3G01380

DIOPT Version :9

Sequence 1:	NP_651562.2	Gene:	CG13978 / 43303	FlyBaseID:	FBgn0039518	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_001326691.1	Gene:	AT3G01380 / 821231	AraportID:	AT3G01380	Length:	1001	Species:	Arabidopsis thaliana

Alignment Length:	981	Identity:	254/981 - (25%)
Similarity:	443/981 - (45%)	Gaps:	180/981 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 LVVHILLMGAILNTYFQHTLLPNL--VPQKTMRELGLEPPADRLVVFVTDGLRAATFLANNGSD- 68
            :.:|.:.|.:|.:.||:..::..:  ||.:..     ||||.|||:.::|||||..|...:...
plant    51 VALHAVYMLSIFDIYFKTPIVHGMDPVPPRFS-----EPPAKRLVLLISDGLRADKFFEPDEEGK 110

  Fly    69 --VPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAASLMHLCYNPGDFDTVFNRSRN 131
              .|.|::|.:.|||.|:|....||.:||||:||.|||:|||:|.......||.:||:|||:||:
plant   111 YRAPFLRNIIKNQGRWGVSHARPPTESRPGHVAIIAGFYEDPSAVTKGWKANPVEFDSVFNQSRH 175

  Fly   132 MIGWAHSYIVGYFVK-LSHGGAPLRFDSY---MERDLPEKLTCDKWAFDKVENFLR--NVD-NVR 189
            ...:....|:..|.. |.|.    .::||   .|....:....|:|:||:.|..|.  :.| .::
plant   176 TFAFGSPDIIPIFCSALPHS----TWNSYPHEYEDFATDASFLDEWSFDQFEGLLNRSHADPKLK 236

  Fly   190 EWRNYKPAVFFVYLADMDIAAHRFKPLSKKFFAKLQYTQRGIRNTYELFERVFNDSRTAYLMTSD 254
            |..:....|.|::|...|...|..:|.|..:...::...:.....|.|.|..:.|:||:|:.|:|
plant   237 ELLHQDKLVVFLHLLGCDSNGHAHRPYSSIYLNNVKVVDKIAERVYHLLEDYYRDNRTSYIFTAD 301

  Fly   255 HGMNNEGAHGSGSPLEVETPLFMWGAGVK-------RDEIDAEANFPEK-------------PNI 299
            |||:::|:||.|.|...:|||..||||::       ....|:...|.:|             ..:
plant   302 HGMSDKGSHGDGHPTNTDTPLVAWGAGIQYPKPASGNSHSDSVTTFVDKHAHDMPTPYDWGLRRV 366

  Fly   300 SQVD--QTQLAPLMSSLIGLPPPKNNLALMPVGY--LNVSDEYQAVALHLNVL--QLLSQAEILI 358
            .:||  |..:|||||:|:|||.|.|::..:|:||  ||.::|.:||..:...:  |||.::.|
plant   367 ERVDVNQADIAPLMSTLLGLPCPVNSVGNLPLGYMKLNEAEEVEAVVANTKQILNQLLRKSYI-- 429

  Fly   359 GRHEKAIFYKWLPKFKELHIGVIDQYA-AQFDILKSEGNLTDAMEFCKEYGKLAKKCLTYYNQYY 422
             :...::|:|   .||.|   |...:: :|.|.|.|..:...||:...:...|:.:.|.|:..|.
plant   430 -KSSNSLFFK---PFKPL---VHHSFSLSQIDELISAKSYEAAMKLAVDLRNLSLEGLHYFQTYD 487

  Fly   423 QTPLIVANSMSYMIWFYCLLLQLTR--------LSKKE--KMQRR--GFMTVSTLILAMIGILLI 475
            ...|:...::.|..|...|.|.:.:        |||||  .:|::  |.:.:|       |.||:
plant   488 WLMLMTVITLGYTGWMIVLALHVLQCYSSLSGDLSKKEHLSVQKKDSGKVYIS-------GCLLM 545

  Fly   476 AMME-LQKVPHIAAFYLILPVGMLIMAQAE-----RPVRGYW---------IFHPLWNFGFILVP 525
            |::. |..|.|....|... :||.:....:     |.:||.|         .|..|.....:.|.
plant   546 AILSVLNLVEHSPPLYHAY-IGMTVFLWTQIFSEYRLIRGLWKYLRERRADYFIKLLFAAAVAVV 609

  Fly   526 AVLIMSMTFIIRHLW----VLYGI--SVLLNNRRALRKPSIKLFIWLSLALIVTAILFMEQRTIK 584
            .|.::..:|..|.|:    ::.|:  |:||:.....|. .|.:|:.:|...:          ::.
plant   610 IVELLVHSFTERKLYTWFFLIAGVVASILLHFSIPWRS-GIPVFVCISCWFL----------SVF 663

  Fly   585 GLKTIPVKDYHVLYVS-----MVLAIIRPLILGHRHDPRVWTFNSLTLVVGAFGVYQYKFYES-- 642
            .|....:.|.:.|.|:     :|:::....:..|....:.|  .|:|            |:||
plant   664 TLMPAEIPDNNNLVVTSGAIIIVISLAAKWLDTHAEGNKFW--QSIT------------FHESRT 714

  Fly   643 -VSSYVYVVTWSFLFFAFLSIVYFAKSLPEARKRLELIT----INMIT-----VLSLLTNSWGCL 697
             :.|.:|.:.   :|...:|.|....|.....:..||.:    ||.:.     ||.|.:.: |.|
plant   715 QMCSMLYCIQ---IFLVGVSSVMVFLSTKHRTQNQELHSSHQFINWLVAGSSMVLPLFSAN-GIL 775

  Fly   698 N-----------------------FQIAITEFIFGLQIYE-------ETKETKEIEDAKDEHTSL 732
            :                       |..|:...:....::|       :.||:...|:..:||.::
plant   776 SRLSSIFLGFAPPFLLLSIGYEAVFYSALAVVLMAWILFENASHHSSKVKESSLSENNTEEHITI 840

  Fly   733 QNLKGF-----YRYGYMILLYFYVSFFLAGHWISSFLFKPTTARLFYPHFSLYIAGSLVLLKIFI 792
            .:.:.:     .|...:.::.|.|:||..|::.|...|:.::...|...||.::..:|::.|:||
plant   841 GSDERYLQLSDVRIPLVFMVLFNVAFFGTGNFASIASFEISSVYRFITIFSPFLMAALLIFKLFI 905

  Fly   793 PSVIFICALYAMVPFVRKNARSILISIFMISNAMGLYQYYFIRNRGSWRKIRMFLDQI-LLTHAV 856
            |.::.|||..|:...||.........:.:.|:.|.::.::.::|.|||.:|...:... :::..|
plant   906 PFMLVICAFSAITKLVRVPRLGCYFLVILFSDIMTIHFFFLVKNTGSWMEIGNSISHFGIVSAQV 970

  Fly   857 NFMLLL 862
            .|:|||
plant   971 VFVLLL 976

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	108/317 (34%)
CG13978	NP_651562.2	PigN	414..839	CDD:282796	105/509 (21%)
AT3G01380	NP_001326691.1	GPI_EPT_1	83..397	CDD:293744	108/317 (34%)
AT3G01380	NP_001326691.1	PigN	479..952	CDD:398585	105/509 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	66	1.000	Domainoid score	I3604
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG55072
OrthoDB	1	1.010	-	-		D270107at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm2513
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR12250
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X2480
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.890