Protein Alignment CG13978 and Pigo

DIOPT Version :10

• Sequence 1: NP_651562.2
• Gene: CG13978 / 43303
• FlyBaseID: FBgn0039518
• Length: 898
• Species: Drosophila melanogaster
• Sequence 2: NP_064419.3
• Gene: Pigo / 56703
• MGIID: 1861452
• Length: 1093
• Species: Mus musculus
• Alignment Length: 1065
• Identity: 213/1065 - (20%)
• Similarity: 344/1065 - (32%)
• Gaps: 365/1065 - (34%)

  Fly    47 RLVVFVTDGLR-----------------AATFLANNGSDVPDLKDIYRQQGRIGISRTCAPTMTR 94
            |:|:.:.|.||                 :..||...||    |:.|...|
Mouse    69 RVVLVLIDALRFDFAQPQRSHVPGEPPVSVPFLGKLGS----LQRILESQ--------------- 114

  Fly    95 PGHIAIFAGFHEDPAASLMHL-CYNPGDFDTVFNRSRNMIGWAHSYIVGYFV-KLSHGGAPLRFD 157
            |.|..::....:.|..::..| ....|...|..:...|..  :|:.:....: :|:..|..:.|
Mouse   115 PHHGRLYRSQVDPPTTTMQRLKALTTGSLPTFIDAGSNFA--SHAIVEDNVIQQLNSAGRRVVF- 176

  Fly   158 SYMERDLPEKLTCDKW------AFDKVENF-------LRNVDN-VRE----------WRNYKPAV 198
                      :..|.|      ||.:...|       |..||| :.|          |     .|
Mouse   177 ----------MGDDTWRDLFPGAFSQAFFFSSFNVRDLHTVDNGILEHLYPTLDGGSW-----DV 226

  Fly   199 FFVYLADMDIAAHRFKPLSKKFFAKLQYTQRGIRNTYELFERVFNDSRTAYLMTSDHGMNNEGAH 263
            ...:...:|...|:..|...:...||....:.|:.   |.||:.||  |..::..||||...|.|
Mouse   227 LIAHFLGVDHCGHKHGPHHPEMAKKLSQMDQVIQG---LIERLEND--TLLVVAGDHGMTMNGDH 286

  Fly   264 GSGSPLEVETPLFMWGAGVKRDEIDAEANFPEKPNISQVDQTQLAPLMSSLIGLPPPKNNLA-LM 327
            |..|.|||...||::........:.     ||:|.:  :.|..|.|.::.|:|||.|..|.. :|
Mouse   287 GGDSELEVSAALFLYSPTALFPSVP-----PEEPEV--IPQVSLVPTLALLLGLPIPFGNTGEVM 344

  Fly   328 PVGYLNVSDE--------YQAVALHLNVLQLLSQAEILIGRHEKAIFYKWLPKFKELHIGVIDQY 384
            ...:...||.        .|..|||:|..|:   :..|   |..:...:.| :.||||
Mouse   345 AELFSGGSDSSHPHSSALAQVSALHINAQQV---SRFL---HTYSAATQDL-QVKELH------- 395

  Fly   385 AAQFDILKSEGN------LTDAMEFCKEYGKLAKKCLTYYNQYYQTPLIVANSMSYMIW------ 437
              :...|.|:.:      |.|..|        |:..|:.....:|..|..|.::....|
Mouse   396 --RLQTLFSKASARYQHFLRDPQE--------AEAALSTLTAEFQQFLRGARALCIESWARFSLV 450

  Fly   438 -------------FYCLLLQLTRLSKKEKMQRRGFM-------------------------TVST 464
                         ..|||.....::.       ||:                         |.|.
Mouse   451 RMAGGAALLAAACLLCLLASQLAVAP-------GFLFRPLLLIPVAWGLTWTILYAGVSVTTGSK 508

  Fly   465 LILAMIGILLIA-------------------MMELQKVPHIAAFYLILPVG-----MLIMAQAER 505
            :.|.::|.:..|                   :..|..||......|::.:.     ..::|:|..
Mouse   509 IDLVVLGAVAAAGSLLPFLWKAWVSRGSKRPLAPLLPVPRPVLILLLIRLATFFSDSFVVAEARA 573

  Fly   506 P--VRGYWIFHPL----WNFGFILVPAVLIMSM------TFIIRH-----LWVLYGISVLLNNRR 553
            .  :.|..:|..:    |. |.:|.|..|.||.      |...||     ||:  ||.:||..|.
Mouse   574 TPFLLGSLVFFLVAQLHWE-GQLLPPKPLTMSRLGSSAPTAPPRHSGAHALWL--GIGLLLFTRL 635

  Fly   554 A-------LRKPSIKLFIWLS-LALIVTAILFMEQRTIKGLKTIPVKDYHVLYVSMVLAIIRPLI 610
            |       ...|:.:...||| ||.:|..                 :..::.|.:.|.|::..|:
Mouse   636 AGLFHRCPEETPACRSSPWLSPLASMVGG-----------------RAKNLWYGACVGALVALLV 683

  Fly   611 LGHRHDPRVWTFNSLTLVVGAFGVYQYKFYESVSSYVYVVTWSFLFFAFLSIVYF--AKSLPEAR 673
            :     .|:|             :.:|...:|....|..|.|........:..|:  |....||.
Mouse   684 V-----VRLW-------------LRRYGNLKSPEPPVLFVRWGMPLMVLGTAAYWALASGAEEAP 730

  Fly   674 KRLE-----------------------LITINMITVL-----------SLLTNSWGCLNFQIAIT 704
            .||.                       |:....:|||           ::||...|....| |..
Mouse   731 PRLRALVAGASAVLPRAVMGLAALGLVLLLWRPVTVLVKAGAATSRTRTILTPFSGPPTSQ-ADL 794

  Fly   705 EFIFGLQIYEETKETKEIEDAKDEHTSLQNLKGFYRYGYMILLYFYVSFFLAGHWISSFLFKPTT 769
            :::.. |||...:|..:   .:.|.|..|        |.:.:..:.:....:...:::.|.
Mouse   795 DYVVP-QIYRHMQEEFQ---GRLERTKAQ--------GPITVAAYQLGSVYSAAMVTALLL---- 843

  Fly   770 ARLFYPHFSLYIAG-SLVLLKIFIPSVIFICALYAMVPFVRKNARSIL---ISIFMISNAMGLYQ 830
              |.:|...|::.. |||.|.:|:.|.:.:..|.|..|.......::|   :|.:::......|.
Mouse   844 --LAFPLMLLHVERVSLVFLLLFLQSFLLLHLLAAGTPVATPGPFTVLWQAVSAWVLLATQTFYS 906

  Fly   831 ----------------YYFIRNRGS--WRKIRMFLDQILL---THAVNFMLLLGISLAKI--FLA 872
                            ..|....||  |      |..:|:   |.|.:.:..:|..|..:  ||.
Mouse   907 TGHQPVFSAIHWHAAFVGFPDGHGSSTW------LPALLVGANTFASHLLFAVGCPLLLLWPFLC 965

  Fly   873 NTTMERPGQKRARTTRSNLAAAETE 897
                ||.|.||    |..|..:|:|
Mouse   966 ----ERQGPKR----RQPLPGSESE 982

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	72/324 (22%)
		PigN	413..839	CDD:461508	99/574 (17%)
Pigo	NP_064419.3	GPI_EPT_3	64..344	CDD:293747	72/323 (22%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	971..991		6/16 (38%)