DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13978 and enpp5

DIOPT Version :9

Sequence 1:	NP_651562.2	Gene:	CG13978 / 43303	FlyBaseID:	FBgn0039518	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_005160520.3	Gene:	enpp5 / 563498	ZFINID:	ZDB-GENE-041014-10	Length:	512	Species:	Danio rerio

Alignment Length:	357	Identity:	67/357 - (18%)
Similarity:	112/357 - (31%)	Gaps:	149/357 - (41%)

- Green bases have known domain annotations that are detailed below.

  Fly    91 TMTRPGHIAIFAGFHEDPAASLMHLCYNPGDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLR 155
            |.|.|.|..:..|.|.:....:.:..|:|     :.|||.::.|                  |..
Zfish   111 TKTYPNHYTLVTGLHAESHGVVANEMYDP-----IHNRSFSIEG------------------PEV 152

  Fly   156 FDS-YMERDLPEKLTCDK---------WAFDKV-------ENFLR---------NVDNVREWRNY 194
            :|: :.|...|..:|..|         |....|       .::||         .|..:.:|.:.
Zfish   153 YDAWWWEEAEPLWVTNQKAGRKSGAAMWPGSDVAIGGTFPTHYLRYNASMLFETRVQKLIDWFSG 217

  Fly   195 KPAVFF--VYLADMDIAAHRF---KPLSKKFFA----KLQYTQRGIRNTYELFERVFNDSRTAYL 250
            ..|:.|  :|..:.|.:.|..   .||.....|    ||.:.:..:::. .|:::|      ..:
Zfish   218 PEAINFGVLYWEEPDESGHNLGPESPLMDVVLADIDEKLGFLREKLKSA-GLYDKV------NLI 275

  Fly   251 MTSDHGMNNEGAHGSGSPLE--VETPLFMW-----GAGV------------------------KR 284
            :|||||| .:.:|.....|:  |...|:.|     ..|:                        |:
Zfish   276 VTSDHGM-TQLSHDKIIELDTYVSRDLYTWIDKSPVVGILPKEGKLEEVYGLLKNANPNMVVYKK 339

  Fly   285 DEIDAEANFPEK-----------------------------------PNISQV----------DQ 304
            :||....::...                                   ||:..|          |.
Zfish   340 EEIPDHYHYRHNARIMPLIIEVKEGWTVMQNRNGSFMLGNHGYNNSLPNMHPVFVARGPAFRRDY 404

  Fly   305 TQ-------LAPLMSSLIGLPPPKNNLALMPV 329
            |:       |.|||.|::.|.|..||.:|..|
Zfish   405 TKTSMRSVDLYPLMCSILALKPLPNNGSLSSV 436

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	66/354 (19%)
CG13978	NP_651562.2	PigN	414..839	CDD:282796
enpp5	XP_005160520.3	Enpp	71..422	CDD:293742	61/341 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900