DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13978 and enpp1

DIOPT Version :9

Sequence 1:	NP_651562.2	Gene:	CG13978 / 43303	FlyBaseID:	FBgn0039518	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_005160498.1	Gene:	enpp1 / 562399	ZFINID:	ZDB-GENE-040724-172	Length:	878	Species:	Danio rerio

Alignment Length:	322	Identity:	59/322 - (18%)
Similarity:	99/322 - (30%)	Gaps:	108/322 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 LVVFVTDGLRAATF------------LANNGSDVPDLKDIYRQQGRIGISRTCAPTMTRPGHIAI 100
            |::...||.||...            |...|:..|.::..|             ||.|.|.|..|
Zfish   179 LLLVSLDGFRAGYMNAYSALLPAIRKLRECGTSTPYMRPAY-------------PTKTFPNHYTI 230

  Fly   101 FAGFHEDPAASLMHLCYNPG-------DFDTVFN------------RSRNMIGWAHSYIVGYFVK 146
            ..|.:.:....:.:..|:..       ..|..||            ..:|.:..|..:..|..||
Zfish   231 VTGLYPETHGIVDNKMYDVNRNASFSLKVDEKFNPLWYQGEPVWITAMKNHLKTATFFWPGSDVK 295

  Fly   147 LSHGGAPLRFDSYMERDLPEKLTCDKW-AFDKVENFLRNVDNVREW----RNYKPAVFFVYLADM 206
            : ||..|                 |.| .:::...|.:.:..:.:|    ...:|..:.:|..:.
Zfish   296 V-HGRYP-----------------DYWIKYNRNILFEKRIAQIFQWLHLPEGERPDFYTLYFEEP 342

  Fly   207 DIAAHRFKPLSKKFFAKLQYTQRGI---------RNTYELFERVFNDSRTAYLMTSDHGMNN--- 259
            |.:.|::.|:|.:....|....|.|         ||.::....|         :.|||||..
Zfish   343 DASGHKYGPMSTQVIEALINVDRLIGMLMDGLKERNLHKCVNVV---------LVSDHGMEEASC 398

  Fly   260 -------------------EGAHGSGSPLEVETPLFMWG-AGVKRDEIDAEANFPEKPNISQ 301
                               :|......|..|....|.:. .|:.::....|.|.|.||.:.:
Zfish   399 KKAAYVSNYLDNINDITVIQGPAARVRPRHVPEEFFSFDYEGLVKNLSCREPNQPMKPYLKE 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	59/322 (18%)
CG13978	NP_651562.2	PigN	414..839	CDD:282796
enpp1	XP_005160498.1	Somatomedin_B	70..108	CDD:279385
		SO	112..155	CDD:197571
		Enpp	177..545	CDD:293742	59/322 (18%)
		Phosphodiest	179..505	CDD:279931	59/322 (18%)
		NUC	644..862	CDD:294067
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900