DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG13978 and Enpp3

DIOPT Version :9

Sequence 1:	NP_651562.2	Gene:	CG13978 / 43303	FlyBaseID:	FBgn0039518	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_062243.2	Gene:	Enpp3 / 54410	RGDID:	708511	Length:	875	Species:	Rattus norvegicus

Alignment Length:	267	Identity:	51/267 - (19%)
Similarity:	89/267 - (33%)	Gaps:	98/267 - (36%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 EPPADRLVVFVTDGLRAATFLANNGSDVPDLKDIYRQQGRIGISRTCA----------PTMTRPG 96
            :||   :::|..||.| |.:|....:.:|::..:          :||.          ||.|.|.
  Rat   159 QPP---VILFSMDGFR-AEYLQTWSTLLPNINKL----------KTCGLHSKYMRAMYPTKTFPN 209

  Fly    97 HIAIFAGFHEDPAASLMHLCYNPGDFDTVFNRS--------RNMIGWAHSYIVGYFVKLSHGGAP 153
            |..|..|.:.:     .|...:...:|...|::        .|...|:...|  :...:..|
  Rat   210 HYTIVTGLYPE-----SHGIIDNNMYDVYLNKNFSLSSVEKSNPAWWSGQPI--WLTAMYQG--- 264

  Fly   154 LRFDSYMERDLPEKLTCDKWAFDKV------ENFLRNVDN----------VREW----RNYKPAV 198
            |:..||.            |....|      .|..||..|          :.:|    :..:|:.
  Rat   265 LKAASYY------------WPGSDVAVNGSFPNIYRNYSNSVPYESRIATLLQWLDLPKAERPSF 317

  Fly   199 FFVYLADMDIAAHRFKPLSKKFFAKLQYT------------QRGIRNTYELFERVFNDSRTAYLM 251
            :.:|:.:.|.|.|:..|:|......||..            ||.:.|...:            ::
  Rat   318 YTIYVEEPDSAGHKSGPVSAGVIKALQLVDDAFGMLMEGLKQRNLHNCVNI------------IV 370

  Fly   252 TSDHGMN 258
            .:||||:
  Rat   371 LADHGMD 377

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	51/267 (19%)
CG13978	NP_651562.2	PigN	414..839	CDD:282796
Enpp3	NP_062243.2	SO	51..94	CDD:197571
		Cell attachment site. /evidence=ECO:0000255	79..81
		SO	95..138	CDD:197571
		Phosphodiesterase	141..510		51/267 (19%)
		Phosphodiest	162..486	CDD:396300	49/261 (19%)
		Nuclease	605..875
		NUC	608..867	CDD:238043
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900