DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13978 and Enpp6

DIOPT Version :9

Sequence 1:	NP_651562.2	Gene:	CG13978 / 43303	FlyBaseID:	FBgn0039518	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	NP_796278.1	Gene:	Enpp6 / 320981	MGIID:	2445171	Length:	440	Species:	Mus musculus

Alignment Length:	303	Identity:	54/303 - (17%)
Similarity:	105/303 - (34%)	Gaps:	89/303 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RLVVFVTDGLRAATFLANNGSDVPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAAS 111
            :|:|.:.||.|:.....:..:.:|..::|..:..::.......|:::.|.:..:..|.|.:....
Mouse    25 KLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQM 89

  Fly   112 LMHLCYNP---GDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKW 173
            :.:..::|   ..||...||...|..|            .:|..||.......|   .|:....|
Mouse    90 IGNYMWDPRTNKSFDIGVNRDSLMPLW------------WNGSEPLWITLMKAR---RKVYMYYW 139

  Fly   174 AFDKVE-------------------NFLRNV-DNVREWRNYKPAVFFVYLADMDIAAHRFKPLSK 218
            ...:||                   ||...| |.:...::.:..:..:|...:|:..|.:.|.|.
Mouse   140 PGCEVEILGVRPTYCLEYKTVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSP 204

  Fly   219 -------------KFFAKLQYTQ-RGIRNTYELFERVFNDSRTAYLMTSDHGMNNEGAHGSGSPL 269
                         |:.  :|:.| ||::....:            ::.|||||
Mouse   205 QRKDALRAVDTVLKYM--IQWIQDRGLQQDLNV------------ILFSDHGM------------ 243

  Fly   270 EVETPLFMWGAGVKRDEIDAEANFPEKPNISQVDQTQLAPLMS 312
               |.:| |     .|::...:|:....::.||...  .|::|
Mouse   244 ---TDIF-W-----MDKVIELSNYISLDDLQQVKDR--GPVVS 275

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	54/303 (18%)
CG13978	NP_651562.2	PigN	414..839	CDD:282796
Enpp6	NP_796278.1	Phosphodiest	26..357	CDD:366747	54/302 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900