DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG13978 and Enpp6

DIOPT Version :9

Sequence 1:	NP_651562.2	Gene:	CG13978 / 43303	FlyBaseID:	FBgn0039518	Length:	898	Species:	Drosophila melanogaster
Sequence 2:	XP_006253218.1	Gene:	Enpp6 / 306460	RGDID:	1311645	Length:	440	Species:	Rattus norvegicus

Alignment Length:	248	Identity:	46/248 - (18%)
Similarity:	88/248 - (35%)	Gaps:	62/248 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 RLVVFVTDGLRAATFLANNGSDVPDLKDIYRQQGRIGISRTCAPTMTRPGHIAIFAGFHEDPAAS 111
            :|:|.:.||.|:.....:..:.:|..::|..:..::.......|:::.|.:..:..|.|.:....
  Rat    25 KLLVLLLDGFRSDYISEDALASLPGFREIVNRGVKVDYLTPDFPSLSYPNYYTLMTGRHCEVHQM 89

  Fly   112 LMHLCYNP---GDFDTVFNRSRNMIGWAHSYIVGYFVKLSHGGAPLRFDSYMERDLPEKLTCDKW 173
            :.:..::|   ..||...||...|..|            .:|..||.......|   .|:....|
  Rat    90 IGNYMWDPRTNKSFDIGVNRDSLMPLW------------WNGSEPLWITLMKAR---RKVYMYYW 139

  Fly   174 AFDKVE-------------------NFLRNV-DNVREWRNYKPAVFFVYLADMDIAAHRFKPLS- 217
            ...:||                   ||...| |.:...::.:..:..:|...:|:..|.:.|.|
  Rat   140 PGCEVEILGVRPTYCLEYKNVPTDINFANAVSDALDSLKSGRADLAAIYHERIDVEGHHYGPSSP 204

  Fly   218 ------KKFFAKLQY-----TQRGIRNTYELFERVFNDSRTAYLMTSDHGMNN 259
                  |.....|:|     .:||::|...:            ::.|||||.:
  Rat   205 QRKDALKAVDTVLKYMTQWIQERGLQNDLNV------------ILFSDHGMTD 245

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG13978	NP_651562.2	GPI_EPT_1	42..328	CDD:293744	46/248 (19%)
CG13978	NP_651562.2	PigN	414..839	CDD:282796
Enpp6	XP_006253218.1	Enpp	24..397	CDD:293742	46/248 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1524
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900