Protein Alignment side and side-VII

DIOPT Version :10

• Sequence 1: NP_001247334.1
• Gene: side / 43300
• FlyBaseID: FBgn0016061
• Length: 986
• Species: Drosophila melanogaster
• Sequence 2: XP_061497694.1
• Gene: side-VII / 1274072
• VectorBaseID: AGAMI1_004651
• Length: 918
• Species: Anopheles gambiae
• Alignment Length: 950
• Identity: 280/950 - (29%)
• Similarity: 411/950 - (43%)
• Gaps: 184/950 - (19%)

  Fly    70 LVLLTCLQQLKSVSADEESQDFQKNIPARLVWAALGKTVELPCDLTPPTSQDSVKLLLWFKDTTG 134
            |:||..:|...||          |::|...:.|.:|:|:.|||:::.....|:|.|:||:::..|
Mosquito    12 LLLLFIVQYTASV----------KDVPVVAMEALVGETIYLPCNVSTHEPGDNVVLVLWYREDKG 66

  Fly   135 IPLYSLDSRGGNVKLAPHAAIASDLGQRLFFSIGDNPKDSRLQINDVKPEDGGVYRCRVDFFNSP 199
            .|:||.|:||..|..|...:..|..|.|.:|.....|  ..|.:.:|:..|.|:|||||||..:.
Mosquito    67 SPIYSADTRGREVGSAKRWSDDSMFGDRAYFQFEKEP--GELAVQNVRETDSGMYRCRVDFIVAQ 129

  Fly   200 TRNFRHNLTLVVPPEEPRIFDAQGKEISQMAGPFREGYELFLCCQVRGGRPPPKVTWWRDDTELI 264
            |||...|||::||||...|.|..|.|.:.:|||:.||..:.|.|.|.||||.|.|||:||...::
Mosquito   130 TRNSVVNLTIIVPPERMVIRDQLGMERTTVAGPYSEGDNIKLRCDVYGGRPTPTVTWYRDGVAMV 194

  Fly   265 GTSHTSVEEGATVMVNQLLIGTTTRDFYGIRIECRAQGTRLVDPVRKDVTVQVYLKPVRVKIATP 329
              :.|........:.:::.:|..||.....::.|||......:||.:.|.:.:...|:.:::...
Mosquito   195 --ADTKYMPLGKHLRSEIALGPLTRQDLHTKLVCRASNHARANPVEQSVQIDMNFAPLNIRLIGA 257

  Fly   330 NELLTAGQPMPIRCESWGSYPAAKITWLLDGEPIRNAEVTVHSDKEDGNITTSILTLKVTSENDN 394
            ::.|:||:...:.|:|.||.|||.|||.|||..:..::.|..:   |||.|||.|::.:...:..
Mosquito   258 HQPLSAGRRYDLLCQSAGSRPAASITWFLDGVRLDKSKETTSA---DGNQTTSTLSIVLNRTDAG 319

  Fly   395 AELTCRATNPWFSGGAIEDKRIIRVAYPPTVSVHLANE-DPSRLVTRAEGQNVTFKCRADARPPV 458
            ..|:|:|.|.:....|:||...:.:.|.|..||.|.:. ||..:   .||.:|.|.|...|.|.|
Mosquito   320 KYLSCKAYNTYVQSDALEDGWQLDIQYVPDASVRLGSSLDPDAI---REGTDVYFDCIVKAHPAV 381

  Fly   459 TSYSWFKNGMRMSGE-------STEIMHLTQLERESAGAYACGATNTEGETRSSSLTLKVQFSPR 516
            ....|..|...::..       |...:.|..:.|.:||.|.|...|.|||..|.:..|.|.::|.
Mosquito   382 YKVEWKHNNKTLTRNISQGVIVSKHSLVLQGVSRTTAGNYTCVGFNAEGEGSSPTFELNVMYAPT 446

  Fly   517 CKSGTEQTSIGAVSLHSILVKCEVDADPPDSVRFSWTYNNTRNVSPVLNSRIQSNGLASTVTYLP 581
            | :..:....|.....:..::|.|||:||| |.|.||:||:.....|..|.|...|.:|.|:|.|
Mosquito   447 C-APNQPRVYGVAKQENAEIRCVVDANPPD-VEFKWTFNNSAESIDVQASHISRLGTSSIVSYTP 509

  Fly   582 QTDSELITLACWASNAVGRQTTPCLVHILPANTPEAPKACELRN--DTVLEVVCVAGSDGGLSQY 644
            ..:.:..||.|.|:|.:|:|..||:.||:.|..|:....|.:.|  .|.|.|.|..|.:|||:|.
Mosquito   510 MIELDYGTLLCSATNKIGKQRQPCVFHIIAAGRPDQVHNCTVANVSMTSLAVRCYEGFNGGLAQS 574

  Fly   645 FMLEVVGGDPLYSGDPGGSAGQGRGQFSEAIGLGDNEISTLNDQATSAPIFRMQENSPQFRLNNL 709
            |.||                            |.|:....:....|| |:       |:|.:.||
Mosquito   575 FFLE----------------------------LRDSHSQEMRFNNTS-PV-------PRFTVPNL 603

  Fly   710 EPGREYQFLVYAVNAKGRSEPPVVIENVRVAAQLGPYDESILSE------DPTPAETTHHGGGGV 768
            .|...||..|||.|:||||||.|    :..|.|..|..:...||      .|.|...|
Mosquito   604 HPSAVYQLAVYAFNSKGRSEPYV----MSAATQRLPEKQMKDSEKVERPRSPLPLTPT------- 657

  Fly   769 GGSGSSSGLGTGASTGSGPEKQSTLLILAAVVVIGAVVVTSIIVAGIVVVC----RHRPRPPEPQ 829
                .|..:|                 |||.|:||:..    ||..:...|    |......:..
Mosquito   658 ----LSIAIG-----------------LAAAVLIGSCA----IVLALKFPCGASGRRNKETAQGT 697

  Fly   830 EVRKSMRPARNDVPSMYIEEDELNELEEGGGRAADIRARVAPPNSHLCGGGGMPMPGGVGSSGGA 894
            .||.| .|..:| .|:..:|.:.||.:|   :..|:                  :|..:.|.
Mosquito   698 TVRTS-SPGPSD-KSVASKEYDGNESDE---KNPDV------------------IPDTIDSD--- 736

  Fly   895 IVGVAGPHHYISE----SFIQYAQPSLNGDVLLPLLVTSSQPCST--------------NSTISS 941
                 ....||..    |.|....||       .||:|::.|..|              :||:..
Mosquito   737 -----DQMEYIKRRQHISTIDTNSPS-------RLLLTTTAPNQTFIGSSMAAALHANHSSTLGY 789

  Fly   942 VVL--AMPQA-------KLCPDP-----ASRNTAWPPEYP 967
            ..|  ..|||       .:|..|     ||..|...|.:|
Mosquito   790 CTLRNGTPQASNSITNVSMCHMPSTFTTASHTTCTLPRHP 829

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
side	NP_001247334.1	V-set	95..211	CDD:462230	43/115 (37%)
		Ig	211..301	CDD:472250	32/89 (36%)
		Ig strand B	239..243	CDD:409353	1/3 (33%)
		Ig strand C	253..257	CDD:409353	2/3 (67%)
		Ig strand E	281..285	CDD:409353	0/3 (0%)
		Ig strand F	295..300	CDD:409353	1/4 (25%)
		Ig	326..408	CDD:472250	28/81 (35%)
		Ig strand B	339..343	CDD:409353	0/3 (0%)
		Ig strand C	353..357	CDD:409353	2/3 (67%)
		Ig strand E	384..388	CDD:409353	1/3 (33%)
		Ig strand F	396..401	CDD:409353	2/4 (50%)
		Ig_2	442..511	CDD:464026	23/75 (31%)
		FN3	<700..735	CDD:238020	18/34 (53%)
side-VII	XP_061497694.1	None