DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG42534 and TIP1

DIOPT Version :9

Sequence 1:	NP_651560.2	Gene:	CG42534 / 43298	FlyBaseID:	FBgn0260487	Length:	1555	Species:	Drosophila melanogaster
Sequence 2:	NP_197535.2	Gene:	TIP1 / 832157	AraportID:	AT5G20350	Length:	620	Species:	Arabidopsis thaliana

Alignment Length:	377	Identity:	104/377 - (27%)
Similarity:	163/377 - (43%)	Gaps:	64/377 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   233 VHWATVCGEVESL-RAVLAAGASVAKPDANGGTPLHYAAQMCGASKQDSKQQASSSNSSRLSLEI 296
            |:.|...|::|.| |.|...|:||::|||.|    :||.|.             |:.::|::  :
plant    35 VYTAAAYGDLEKLHRLVECEGSSVSEPDALG----YYALQW-------------SALNNRVA--V 80

  Fly   297 LGILLSHPQSSVDVQDKDGRQPLLWAASAGSAKAVIALVKAGARVESSDKDGLTALHCAGSRGHT 361
            ...|:.| ...|:..|..|:..|.|:|..|:.:....|::.||||:::|..|..|.|.|...|.|
plant    81 AQYLIEH-GGDVNATDHTGQTALHWSAVRGAIQVAELLLQEGARVDATDMYGYQATHVAAQYGQT 144

  Fly   362 ECIDTLIGLCGAPTDLIDSNGCTALHYAVTLGHADATARLLDLEADPNRQDRKGRTPAHCGCSKG 426
            ..:..::....|..|:.|::|.:.||:|...|.||:...||.|:|...|||::|.||.|....:|
plant   145 AFLCHVVSKWNADPDVPDNDGRSPLHWAAYKGFADSIRLLLFLDAYRGRQDKEGCTPLHWAAIRG 209

  Fly   427 QFETLKLLKERG--ANLWLRNAKGDLPLHEAAASGRRELLEWLLAQR---PKQVNTTSNDGRSLL 486
            ..|...:|.:.|  .:|.:.:..|..|...||....|::..:|...|   .|:.:.:|..|| |.
plant   210 NLEACTVLVQAGKKEDLMITDKTGLTPAQLAAEKNHRQVSFFLGNARSLLEKRCDGSSPLGR-LS 273

  Fly   487 HIAAANDYTDMCKLLLDYGADVNAVYRNSRGLV-----LTPLDGAL---------------QRGH 531
            .:..|.....|..|||       .||.||..|.     ||...|||               .|..
plant   274 KLGLAPVLWIMILLLL-------LVYTNSVVLASNLPKLTTGIGALAWLGFILATAGLFLFYRCS 331

  Fly   532 RSTAKFLQAN--------GGQPANKVRLSSRR--TGNPFHETNATDMVRPLK 573
            |....:::.|        ..:|..|:.|::..  .||.........::|||:
plant   332 RKDPGYIRMNIHDPQTMKDDEPLLKIELNNPALLAGNWTQLCATCKIIRPLR 383

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42534	NP_651560.2	Ank_2	127..226	CDD:289560
		ANK	193..335	CDD:238125	28/102 (27%)
		ANK repeat	195..226	CDD:293786
		Ank_5	214..269	CDD:290568	14/36 (39%)
		ANK repeat	228..259	CDD:293786	10/26 (38%)
		ANK repeat	314..345	CDD:293786	10/30 (33%)
		Ank_2	319..412	CDD:289560	31/92 (34%)
		ANK	345..468	CDD:238125	38/124 (31%)
		ANK repeat	347..379	CDD:293786	8/31 (26%)
		ANK repeat	381..412	CDD:293786	12/30 (40%)
		ANK	409..538	CDD:238125	41/153 (27%)
		ANK repeat	414..479	CDD:293786	17/69 (25%)
		ANK repeat	419..445	CDD:293786	6/27 (22%)
		Ank_2	420..511	CDD:289560	23/95 (24%)
		ANK repeat	481..511	CDD:293786	8/29 (28%)
		Ank_2	486..>545	CDD:289560	18/86 (21%)
		ANK repeat	516..542	CDD:293786	9/53 (17%)
TIP1	NP_197535.2	Ank_2	38..128	CDD:403870	32/109 (29%)
		PHA03095	55..>252	CDD:222980	64/216 (30%)
		ANK repeat	64..95	CDD:293786	9/50 (18%)
		ANK repeat	97..128	CDD:293786	10/30 (33%)
		ANK repeat	197..226	CDD:293786	8/28 (29%)
		DHHC	256..506	CDD:418707	32/136 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	1	1.000