DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG42534 and Ankrd16

DIOPT Version :9

Sequence 1:	NP_651560.2	Gene:	CG42534 / 43298	FlyBaseID:	FBgn0260487	Length:	1555	Species:	Drosophila melanogaster
Sequence 2:	NP_001028870.1	Gene:	Ankrd16 / 307102	RGDID:	1311405	Length:	370	Species:	Rattus norvegicus

Alignment Length:	366	Identity:	96/366 - (26%)
Similarity:	141/366 - (38%)	Gaps:	51/366 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    95 PETDPDPAQLTVSQSQSSSTVARRRLAEGC---------------TSLMYACQRG--DIVQVLAQ 142
            |..||......|.:.|..:......:|.||               |.|.:|.:.|  ||:..|.:
  Rat     3 PPGDPRRLCRLVQEGQLRALREELEVAGGCWDPEMFRGSQGPAGDTLLHFASRHGRQDILAYLVE 67

  Fly   143 MREKPELLRQRDRSHRNALHYCAAQDSEGSKDLVAAASIAIAAPELLESADEDGFTPLHLAVIQG 207
            .....  :...:|.::..||..|   |.|.:|.|.......|..:.|:.||   :|||.:|..:.
  Rat    68 AWSMD--IEAANRDYKRPLHEAA---SMGHRDCVRYLLGRGAVVDSLKKAD---WTPLMMACTRK 124

  Fly   208 NLAMVNLLLANKADVNAVDNEGHSVVHWATVCGEVESLRAVLAAGASVAKPDAN-GGTPLHYAAQ 271
            ||.::..|:.:.|:....:.:|.:..|.|:..|:...||.:|.....|.|.::. ..||||.||
  Rat   125 NLEVIQDLVEHGANPLLKNKDGWNSFHIASREGDPVILRYLLTVCPDVWKTESKIRRTPLHTAA- 188

  Fly   272 MCGASKQDSKQQASSSNSSRLSLEILGILLSHPQSSVDVQDKDGRQPLLWAASAGSAK-AVIALV 335
            |.|.                  .|.:..||.......|.:|..|..|.:.|...|... |.:.|.
  Rat   189 MHGC------------------FEAVQELLERCHYEPDCRDNCGVTPFMDAIQCGHVSIAKLLLE 235

  Fly   336 KAGARVESSDKDGLTALHCAGSRGHTECIDTLIGLCGAPTDL---IDSNGCTALHYAVTLGHADA 397
            ...|...::|..|..|||.|...|..|.|..|:  ||...|:   ..|:..|||.||...|....
  Rat   236 NHEACSSATDSLGAQALHRAAVTGQDEAIRFLV--CGLGIDVDVRAKSSQLTALLYAAKEGQTST 298

  Fly   398 TARLLDLEADPNRQDRKGRTPAHCGCSKGQFETLKLLKERG 438
            ...||.|.||.|..|.:.|:..|..|:.......:.|::.|
  Rat   299 VQTLLSLGADINSTDERNRSALHLACAGQHAACARFLRQSG 339

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG42534	NP_651560.2	Ank_2	127..226	CDD:289560	26/100 (26%)
		ANK	193..335	CDD:238125	36/143 (25%)
		ANK repeat	195..226	CDD:293786	8/30 (27%)
		Ank_5	214..269	CDD:290568	15/55 (27%)
		ANK repeat	228..259	CDD:293786	9/30 (30%)
		ANK repeat	314..345	CDD:293786	7/31 (23%)
		Ank_2	319..412	CDD:289560	31/96 (32%)
		ANK	345..468	CDD:238125	32/97 (33%)
		ANK repeat	347..379	CDD:293786	12/34 (35%)
		ANK repeat	381..412	CDD:293786	12/30 (40%)
		ANK	409..538	CDD:238125	7/30 (23%)
		ANK repeat	414..479	CDD:293786	5/25 (20%)
		ANK repeat	419..445	CDD:293786	4/20 (20%)
		Ank_2	420..511	CDD:289560	4/19 (21%)
		ANK repeat	481..511	CDD:293786
		Ank_2	486..>545	CDD:289560
		ANK repeat	516..542	CDD:293786
Ankrd16	NP_001028870.1	ANK 1	45..75		7/31 (23%)
		ANK	46..166	CDD:238125	33/127 (26%)
		ANK repeat	46..77	CDD:293786	7/32 (22%)
		Ank_2	50..143	CDD:289560	26/100 (26%)
		ANK repeat	79..110	CDD:293786	8/33 (24%)
		ANK 2	79..108		8/31 (26%)
		ANK repeat	112..143	CDD:293786	10/33 (30%)
		ANK 3	112..141		10/31 (32%)
		ANK 4	145..174		8/28 (29%)
		ANK 5	179..209		11/48 (23%)
		ANK	181..335	CDD:238125	50/174 (29%)
		ANK repeat	181..211	CDD:293786	12/48 (25%)
		Ank_2	184..278	CDD:289560	31/114 (27%)
		ANK repeat	213..245	CDD:293786	7/31 (23%)
		ANK 6	213..242		7/28 (25%)
		ANK repeat	247..278	CDD:293786	12/32 (38%)
		ANK 7	247..277		12/31 (39%)
		Ank_2	252..339	CDD:289560	28/88 (32%)
		ANK repeat	281..313	CDD:293786	13/31 (42%)
		ANK 8	282..311		11/28 (39%)
		ANK 9	315..344		5/25 (20%)
		ANK repeat	315..339	CDD:293786	4/23 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X100
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.000