Protein Alignment CG3339 and DNHD1

DIOPT Version :9

• Sequence 1: NP_001036762.2
• Gene: CG3339 / 43295
• FlyBaseID: FBgn0039510
• Length: 4842
• Species: Drosophila melanogaster
• Sequence 2: NP_653267.2
• Gene: DNHD1 / 144132
• HGNCID: 26532
• Length: 4753
• Species: Homo sapiens
• Alignment Length: 5271
• Identity: 1036/5271 - (19%)
• Similarity: 1806/5271 - (34%)
• Gaps: 1528/5271 - (28%)

  Fly   496 QVLLPALSEGAAAVASSPSPDDQQQLWRFCHEDVFG------QTLDGFSLQLLE-LRQVFEAAVQ 553
            ::||..|....:||....||    ..||:.|. |.|      :.|.| .|.||. |.|::..|..
Human    59 ELLLAELRTLFSAVLQDSSP----AAWRYLHA-VLGLLPPYRELLVG-HLDLLPFLEQLYCWAPW 117

  Fly   554 FQQLEKLEVGGLRGKILTERVREIFGEFKVLFEQWSNVDIDLTATVASKWKCFRREQTLF----- 613
            .|....|:   |.|.|:     :.|.....|.:..|:.|            |..:::.|.
Human   118 VQTHLHLD---LLGAIV-----QAFPPDSSLLDSASHAD------------CCPQKRRLHHRPPC 162

  Fly   614 ---------FSRMQLLEQKLATVLLQAFEQCHSWMHLLRLTLMFGSLLQREAVRPELARVLPHIL 669
                     :||.|:.|: |||           |:..|.|              |||.|.|.
Human   163 PACPFVQAQWSRQQVKEE-LAT-----------WLRPLTL--------------PELQRCLG--- 198

  Fly   670 FIYDTEMEQLEDSVGEVLLGYEIRGLAALP--LANNFPPIANAMMWLEQHISRCDEFGAKEL-SQ 731
             |...:: .||::|.       :.||:.||  ||.:.|....:.   :...:..:..|.||. ||
Human   199 -IVGAQV-ALEEAVW-------LDGLSLLPLALAADIPVRYESS---DTDNAEVEPVGRKETRSQ 251

  Fly   732 LVEQLLKEKS----------ELQTLPIQWNSLLSRRNILTTKLSNLQMKIWISWHECVDKLIIQG 786
            |..::.:||:          |...|..|..:.|.....| .|:..|.:.:..|.:.....|::..
Human   252 LDYEVPREKAFQKSSTGFSPETSFLDSQVMTALKMERYL-KKIHFLYLNVAPSRYFRPYSLMVVP 315

  Fly   787 LDESVLSRSQDLSQLHLNFSQVLFTLLKETKYLLALQATGSLSGDLFQLPEPLLTLYGHRDAYWE 851
            .|:        ::..|..||.  |.:|    ::..::.:.:::          |..:.|....|:
Human   316 PDK--------VNPEHYIFSP--FGIL----HVHPVEGSETMT----------LGTWHHHCVLWQ 356

  Fly   852 RRIRLIKIGEFYNGIRSGEC--AAAELQLIRNDLASIDEHVEVACQQLTWRNYNDELVAGIFEQS 914
             :::.|...::....:|..|  ....||.:......::.|:.:|.....         ||:...|
Human   357 -QLQFIPFFKYCLLRKSFTCWKKNVRLQGLHRLQKFLENHLLLAVPHFG---------AGLLHIS 411

  Fly   915 RDLFARLQQSHG---------------NLDAILASMRRWSREPLHQRSLYGRNLL-----DLRHQ 959
            |    .||:.|.               :|...||..:..:...||:......::|     |..|.
Human   412 R----LLQELHSVSWLPQELDRCYELLDLQTALAEEKHKALRLLHRCLNLCTSILRLVHEDTYHM 472

  Fly   960 QDRVRLRLLQCDETKMLLNRLLIANFCLFFNYESQEFQLYSRDLSVQEFIREFPEEQR--RQYNK 1022
            |..::.|:..||..:                  :.:..:|.:.:..::..::..:.:.  .|..|
Human   473 QQCLQERVQNCDRIR------------------TGQGSIYLQRVQHKQLEQKLKQAEAWWLQLGK 519

  Fly  1023 YLASVDELICREVREAMRISLEYLYKEMTA-TATATTTPTAPPV--------DPG------CSAG 1072
            :...||.:||:.:       :..|.:::|: .|.....|...|.        |.|      |...
Human   520 FARLVDYMICQSL-------ISVLEEQITSFVANILQAPRQKPFLSSQLVFDDHGQLSHVPCVEN 577

  Fly  1073 MARLVLQQITTPQATSTAGAGASGAPPTANDAPLFEVKLELTETEIRFSPAFDASVENNFQQIVE 1137
            |.:           |.|.|.                                 .||:.:..|:|:
Human   578 MIQ-----------TLTGGL---------------------------------QSVKTSALQVVQ 598

  Fly  1138 QLLLDIKQTCDCMPRIVADNAPSEDDEDDDTATVDYEQELRWEPREDRAQELQERKKKDLELEQE 1202
            .  .|:|.:.|.:       ...|:||::|:                         |.:..:.:.
Human   599 S--ADLKTSSDSL-------YSEEEDEEEDS-------------------------KDEFLMPKF 629

  Fly  1203 QGDPKPQAVQF-----NLLAAAKAYS---------------------QKMECTADGLEMLERA-- 1239
            ||.|......|     .|:...|::.                     :::|...|....:::|
Human   630 QGQPSDAVSIFCGPNVGLVWPWKSHPIAGILEVRGCRLRGQYFPHNYKQLEEDLDNNPKIQQALN 694

  Fly  1240 IRDALADTVAAASAYAAKFQAYAFLWTQQSSEVLAACMQTAREQTHHVSAGGYAIMETFKKE--- 1301
            |:..|.:                        .||....:..||  ||...|.|..::::..:
Human   695 IQQVLLE------------------------GVLCKVQEFCRE--HHWITGIYEFLQSWGPQKLE 733

  Fly  1302 ------IENYNEVHDAIDQCENRECINGWLA----LDIKPL-KYGLLNLAC--------KWSHMC 1347
                  |:||..:...         :|.|.|    :.|:.| |.|||.|:|        ...:..
Human   734 DMRGGPIKNYVTLVSR---------LNVWQARVSSMPIELLTKGGLLLLSCHDVQAEMESKLNSI 789

  Fly  1348 KKWLLRYVQG--------TLKELNAFIARGFETL--QLHIARQDFATLLRVLAIMSEIREREPYA 1402
            :|.:|.:||.        .:.||..|: ..|.|:  .:|...|....|........|:.||..|.
Human   790 RKDILAHVQNECWNLSQQLMTELTDFM-HIFRTINSDIHAIAQCTQKLNEANEQYVELEERMEYV 853

  Fly  1403 DNVFKPLKEIMGLLKTYNVEF--------------------EPQLLRG---IEQLPQQWQQLKHS 1444
            ..:.:.::....|....|...                    :|.||..   ..||...|:..:..
Human   854 RALHELIRNHFSLFSAENEALDISVRRQFGESPIPPCPPPPQPHLLHCPLLAPQLLDMWEAFQFE 918

  Fly  1445 STVKQEALQDTRFH------QQQRVTALIGLH--------------------TCH-LQHYARQFQ 1482
            .:...|.|...| |      ||....||..|.                    |.| |....||||
Human   919 KSQASEFLLSKR-HAIMPKLQQLMAAALAELEGLLAKALSGPFMDPTQDQRSTEHQLVSLERQFQ 982

  Fly  1483 KMPFFRVPCPQVYDVCDEVYLRLHRFRRQQRLYTRWARLLDIQPPDPATLQFCEVE-LRRVKQLW 1546
            .         .|.|:.:     ||.           |..:..:...|..|..|... :.:.:::|
Human   983 N---------TVSDLSE-----LHH-----------AYAIFTEDETPVPLPICGTRPIVQQQRIW 1022

  Fly  1547 DFVRVIESCIVAWHATPWLLIDTDDMEHECKKFTRDLRTLDKCIREWAPYV---HIVGVLRELVA 1608
            ...|||...|..|               :|..|.:           ::|.:   ...|.|.| .|
Human  1023 HLYRVISENISEW---------------KCMAFAK-----------FSPAMAQEKTEGWLTE-AA 1060

  Fly  1609 SLRAITELQNPAITERHWMELM--------QLTKL------SYKCNKSTR--------------L 1645
            .:....||.:|.:  :|.|.::        .||||      |..|....|              |
Human  1061 RMSTTLELHSPVL--QHCMRILGEFRSYLPLLTKLGSLHPQSLNCQCLLRALGLGSLQTIELLTL 1123

  Fly  1646 AQLLTLQLQHHEEDIKNTVDRAIKEMTVTKVLDEIKATW-----------AHLEFELEQHHTRPH 1699
            .||||..|....:.|........:.:...:.:..::..|           .|:.:| .....|..
Human  1124 GQLLTYPLLEFADRINQVWQNENERIHAQETIRRLQRYWEARQLRLLNFILHVPYE-PPASERSK 1187

  Fly  1700 IQLLKVSE-ELIE------------TLDDN-QMQLQNISTSKHIEYL--LDKLT-HWQKVLGGID 1747
            .|:|:..: |:::            .|.|: |..||.:|....||..  |:|:. .|..::.|:.
Human  1188 RQVLRSPQWEVVDKDSGTFILSDYSNLQDSIQESLQVLSKILAIEKSGDLNKIALEWVAIMHGLG 1252

  Fly  1748 TLIVNWFEVQRKWIYLECIFIGSADIRAQLP-ADA-ANFERIDEDFTALL-AKVQEVRVVMQVVL 1809
            .|:..|...|:|||:|..:.   .:::.|.| ||. :.|:.:|:.:..|: ..|.:..|:..||.
Human  1253 ALLEVWLTFQQKWIFLNKVL---HEMKIQFPNADLNSRFKVMDDQYRTLMRISVADPMVLSLVVP 1314

  Fly  1810 RHD-------DVLAQLLQL-QHRLAVCEKALNDYLETKRLAFPRFYFISAADLLDILSNGNNPQV 1866
            ..:       ..|.||||. ...|.....:|...|......|||.:|:|.::|:.:|:.......
Human  1315 SAERSPYFQGQQLQQLLQAGSVELEGIIMSLESVLYGVCAHFPRLFFLSDSELVALLAARLESCE 1379

  Fly  1867 IDRHLIKLFDSILRLQY------ETNT------PN---------ALGMHSKENDEYVPFVSFDPD 1910
            ....:.:.|..:..:.:      |.||      ||         .||...:|.....| :...||
Human  1380 AQLWVRRCFPHVHAVSFRSCPTGEKNTDDWESSPNTQTQVEALAVLGAGGEEVKLQGP-LPLHPD 1443

  Fly  1911 QPAFIVCGGRVELWLR-AIIQQMRSTLHELFRR------ALRVFGEKPR---ELWLYDW------ 1959
            .|.::   ..:|..|| |::..::..:.....|      ||:...::.:   :|::..|
Human  1444 LPKWL---ASLEKCLRLALVHMLQGCVAARLARGPSLGEALKQLPKQNKLYLQLYVQHWIDLVQA 1505

  Fly  1960 -PAQVALCCSQISWTADVNRSFGCMEEGYEGVMKELHKRQIAQLNALINLLL-------GELSPG 2016
             |.|..|...::.|.|::..:.  :|.| ...|..:|.|   :|..|:|.:.       |:..|.
Human  1506 FPWQCVLVAEEVVWRAEMEEAL--LEWG-TLAMVSMHMR---KLEVLVNFMRAQRASQGGQSLPS 1564

  Fly  2017 DRQK--IMTICTIDVHSRDVVGKIIASKVDNSLAFQWQSQLRHRWDDDQ------------AGSS 2067
            .||.  :..:..:.|..||:...:...:|.:...|.|..||::......            ..||
Human  1565 VRQTSLLSALLVMAVTHRDIAQLLEQHQVSDLTDFHWVRQLKYHLGSPHIIPKSPLQSLKTIASS 1629

  Fly  2068 SGRASTAISCGGGDEDCFANICDAEFRYAYEYLGNTSRLVITP--LTDRCYITLTQSLRLRLAGA 2130
            ....|.|.        |:.::....|.|.|||||  .||...|  |.:|..:.|..:|.....|.
Human  1630 EPSLSPAA--------CWIDVLGRSFLYNYEYLG--PRLGPLPSLLPERPALVLLLALEEVACGT 1684

  Fly  2131 TAGPAGTGKTETTKDLGRALGVMVYVFNCSEQMDYKSCGNIYKGLAQTGAWGCFDEFNRICVEVL 2195
            ..||.|.||......|.:|||..:.:..||.|::.:...|...|..|.|||...::.:::...:|
Human  1685 VLGPNGVGKRAIVNSLAQALGRQLVMLPCSPQIEAQCLSNYLNGALQGGAWLLLEKVHQLPPGLL 1749

  Fly  2196 SVVAVQVKTI--------QEAIKMHKT----------QFIFMGERISLEPSVGIFITMNPGYAGR 2242
            |.:..::..:        |||.:...|          ...|....:|:....|..:.:.   |..
Human  1750 SALGQRLGELHHLYAPLYQEASRNTSTIDPTQPQLLGSSFFEKHHVSVRLGYGCLLVLR---ALS 1811

  Fly  2243 TELPENLKTLFRPCAMIVPDFALICEIMLMAEGFQDARLLARKFITLYTLCKELLSKQDHYDWG- 2306
            :.:|.||..|.||.|:.:||...:.|:.|:..|.:||..:|.:....::|.:||:|       |
Human  1812 SAVPANLHLLLRPVALALPDLRQVAELTLLGAGMRDAFQMATRLSKFFSLERELVS-------GP 1869

  Fly  2307 ----LRAIKSVL-----VVAGTLKRDDHSRP------EDQVLMRALRDFNIPKIVTEDVPIF--- 2353
                |..:|.:|     .:..|.:.....:|      |:..|:|:              |:|
Human  1870 LPCRLPLLKQILEDTIRTLNVTKEEPKCQKPRSLAAIEEAALLRS--------------PLFSIL 1920

  Fly  2354 --------MGLIGDLFPALD--VPRKRVFEFEK-TIRRAVNEIKLQPEEGFLMKVVQLQELLDVR 2407
                    .||:..|||:..  :.....::..| .:...:.::.|.|....|..:.||.:.|...
Human  1921 NGLHLHNLRGLLCALFPSASQVLAEPMTYKLMKPLVVEELQQVGLDPSPDILGSLEQLSQALSRA 1985

  Fly  2408 HSVFIVGNAGTGKTKIWQTL---------RETYRIQKLKPV--CHVLNPKALSNDELFGIVNPTT 2461
            ..:.::|.||:|||..|.:|         .|....|..:||  .| |.|..||..|..|.:..:.
Human  1986 SGILLLGPAGSGKTTCWHSLFKIQNRLAAMEDTSTQGCQPVEITH-LYPSGLSPQEFLGWLEGSC 2049

  Fly  2462 REWKDGLFSSIMR-----------EQANMPPGNPKWIVLDGDIDPMWIESLNTLMDDNKILTLAS 2515
              |..|:|..::|           .|.....|...||:.||..:..|::|:..|:.:...|:|.|
Human  2050 --WHHGIFPKVLRAAGQCNNMGQKRQTEESIGIQHWIICDGASNGAWLDSITCLLSELPQLSLPS 2112

  Fly  2516 NERISLKREMRLLFEVGHLKAATPATVSRAGILYINPQDLGWSPYVSSWL-----ETRVDMIERG 2575
            .::|:......||.||......:|..|....:::...:.. |...:|:.:     |.|:......
Human  2113 GQQIARPPGTFLLMEVADTTGISPTVVGCCALVWCGGEQT-WQCILSALMASLPYEYRLQHRTVA 2176

  Fly  2576 ILNALFE-------KYFPC-----LMQ---RQRDFRRITPITDMAMIQMTCHLLECLLDSDEGNA 2625
            .||.:.|       ::..|     |:|   :|.....:..:|.||.|..:  ||:..|...|..|
Human  2177 ELNHMAEVLVPATLRFLTCQGVSSLLQVHGQQAVCAGVAEVTSMARILHS--LLDLHLRLKEEKA 2239

  Fly  2626 DGRGRGSATGGAANPHSLHHGELSHEAMV-------------MALETIFVYATVWSFGSALSQDV 2677
            .|....|.:...|...........:.:.|             :|:.: |::|.:|.||:.|..
Human  2240 PGPEDLSYSDPVAQSFRSSKSSFLNRSQVDSDDVPDKCREHLLAVSS-FLFALIWGFGAHLPS-- 2301

  Fly  2678 IIDWHREFHKWW----------IGEFKDI-KLPSQGTVFDYQLNVQTLKFQPWSELAAHQSLEGQ 2731
                     ::|          |....:. :.|....|||..::.:.....|::.......::|.
Human  2302 ---------RFWPIFDTFIRDSISRLSNYPEPPPSALVFDLHVSPEDGTLVPFTGQYLSSHIKGT 2357

  Fly  2732 IDSETPLQNVLISTAETIRLAYFLKLLIDRNLACMLVGNSGCGKGAIFRQLFGQYANDQELLEVA 2796
            :.:..|       :.:|.||.|.:.||:......:|.|.:..||.|              .:||.
Human  2358 LGTFHP-------SIQTERLLYVVDLLLSGGQPVLLAGEAATGKSA--------------FVEVL 2401

  Fly  2797 VSAATAGDSSHQQQSGNPAGAVVVRRKASSSATPLLTTVQATHFNFYTSSEIFQKMLDRPLEKKS 2861
            |       ..|.....:|                       .|..|  ||...:.:|.|.::
Human  2402 V-------EPHHPYIYSP-----------------------IHPAF--SSSHLRLLLSRGIQ--- 2431

  Fly  2862 GRCYAPSGP------KRRLIYFVNDLNMPEVDAYGTVQP-HTIMRQFMDYRQWYDRQRLQLKDIR 2919
            |:..|...|      |..|::.:.||::...|...:.|| ...:||.|| ...|....|:|:.::
Human  2432 GQTQASPQPGHHQDSKPSLLFLLEDLHLATSDPEKSCQPVLETLRQAMD-GTVYAHSTLELQTLQ 2495

  Fly  2920 -------------HCQFAACMNPTAGSFTIDPRLQRHFCVFSVAPPGEDTLHHIYGSILSSHLES 2971
                         :|:...|           |||.|.|.|.::....:.||...:..|:.:.||.
Human  2496 PTVNFLATVTVPGYCERPLC-----------PRLFRLFTVLALESMTQATLLERHVPIIQAWLER 2549

  Fly  2972 -PSQGFTKEIRSIGSLLVRVGIALHRRVEYAFLPTALKFHYLFNLRDLTGIYQGLMNSVGAPASA 3035
             ||   .:..|::...|||..:.....|...|:|:.|..||.|:|..::.:...|..   .|...
Human  2550 FPS---VERERALARGLVRASVEAWEAVCNCFMPSPLHPHYHFSLHSVSHLLSSLQL---LPNRT 2608

  Fly  3036 GGGG-------------ASGFGG---TICSRPSELMRLYVHEAFRVYHDRL-------------- 3070
            |..|             .||..|   |:......::||::|||.|.:.|||
Human  2609 GSRGFVDYPNHQEHLRRVSGLRGTCLTVMMATRNVVRLWLHEAQRTFCDRLDSPRERSYCAKLLL 2673

  Fly  3071 ---------------------------------------------------------VDPYDIK- 3077
                                                                     .:||.::
Human  2674 VVAQSVFCCGPGPQHLGKDHQESEEEEEEERVPEVESEGELAQWEDFSNSNSETEEEEEPYGLQV 2738

  Fly  3078 ---------------------------------------SFKSSIRDIFKKDF------------ 3091
                                                   :::..:|..||..:
Human  2739 ARVSNSRDPSLTPSIGPVSRGMKESISHKIRQEKGTRASNYRLQVRRSFKTWWQKKPQMDLISPL 2803

  Fly  3092 ---------EDFDEDFVFAEPLIYSHFAQSLVDQKYMPLKSWDSLYQLLIEAQASYNEVVGYMNL 3147
                     ::...|.||::.||..  ..|.....|:. :.|:.|.:.|..:.|   ::....:|
Human  2804 LLPVLLLHPQEKPSDLVFSQELILG--PNSETPNLYLE-RQWEKLEEQLATSAA---QLKLSPHL 2862

  Fly  3148 VLFEDAMIHVCRINRILESPRGNALLI-GVGGSGKQTLARLAAFISSLNVSQIQIKRGFGLL--- 3208
            ........||.|:.|:|..||.:.||: |..|:|:.|...||:.|...:...:.......:|
Human  2863 ARCHSMAQHVARLVRVLARPRQHGLLLSGALGTGRHTAITLASSICQAHFFHLPSGSEEAILQCL 2927

  Fly  3209 -DMREEIGNLYMKVGLKNLASVFLISDAQIPDESILMLINDLLA---SGEIPELFNDDQLDTITN 3269
             |.....|.|...|.|            .:|....|..::.|||   ||..|..:.:..||.|..
Human  2928 RDASWHAGMLSQPVAL------------LVPSGVDLTTLHRLLALATSGSFPGQYTEADLDRIGE 2980

  Fly  3270 -------GIRNEVKQSGTLDTKENCWRYFVEKVRRLLKVVLCFSPVG---------QTLRVRARK 3318
                   |::..:|       ||...:.|.::|...|.:   |..:|         .||.:|..:
Human  2981 HLPRENLGVKQNIK-------KEMVLQRFHQQVCSHLHL---FFLIGDKQAHKQLPSTLFLRLLQ 3035

  Fly  3319 FPAIISRTAIDWFHEWPKSALESVSQKFLNEINGI-LE---------PALVPPIGCFMAYVHGTV 3373
                ::..:||.:..|.::||..|:|..|.....: |:         .|.:|.:...||.:|
Human  3036 ----LATASIDRYEPWDQAALAKVAQHHLEGAQSVPLDDGSWKYPDLQASIPSVAKAMALIH--- 3093

  Fly  3374 NQISRIYLQNE--KRYNYTTPKTFLEYIFLYRKLLVDKNGEFAERIARLQSGMSKLAECARQVDT 3436
              :|..:....  ......||||||:::..:..|......:...:..|:|:.:..|....::..|
Human  3094 --LSATHYHEHLCPALPLVTPKTFLDFLDTFLMLQQQTILKIKNKAQRVQNALENLRMLIKEHGT 3156

  Fly  3437 LKHQLAIQEVQLAAKNAAADKLIVIVSAESEKVKRERYIASEEEKRVRIIEEDVSIKTKMCEEDL 3501
              |...|.:::...|::...     :|...:::::.:.:..::.:..|..|..:        |:|
Human  3157 --HANLIFDLEQQLKDSGKS-----LSMFQQQLEQSKLLYKQQLEECRHQENLI--------ENL 3206

  Fly  3502 RQAEPALVAAQAA------------LNTLNKNNLTELKSFGSPPKAVVNVCAAVMVLLASNGKIP 3554
            .:...||.|.:.|            |:.|...:..|::|:.:||::||.|..|:..|      ..
Human  3207 ARQRDALQAQREAFLEQMSKAFLEPLSQLQVADFEEIRSYRAPPESVVRVTDAMCDL------FH 3265

  Fly  3555 RDRSWKASKLMMVRVDQFLNDLLNYNKDNIHPNIIETLQEYLKDPEFNPDKVVQKSVAAAGLCAW 3619
            .:..|.::|.::...| |..:|:.:.|:.|..:.:..|...||.|..:...:...|..||.|.||
Human  3266 HETGWASAKQLLCTED-FYQELVFFPKEKITDSELIKLHLILKAPGMDDAALRAVSRPAASLAAW 3329

  Fly  3620 VINLHRYHQVFLIVGPKQQALQDSHQELLEARERLQYLKAKI-----NNLE-AKLAEIQAEFENA 3678
            :..:..|........|....||.....|...:.||.|.:.:.     :||. ||:.|......|.
Human  3330 LWAVLHYGLAHCRGLPTDLLLQQVEATLTREQARLGYYQFQAQETLEHNLALAKMVEDAQASHNC 3394

  Fly  3679 VGEKQRCQREADKTAFTIDLAHR--LVNGLANENVRWKESVQSLLAKIGTLPGDILLISSFLSYV 3741
            |. |...|.:..:       .|:  :...|......|...:|.|..:..|:.||.||.|:.:.|:
Human  3395 VA-KTLSQAQCGQ-------YHKWPMKAALLTPMRAWTTQLQKLKGRCMTVFGDTLLCSAAIIYL 3451

  Fly  3742 GCFTRRYREELQHKMWLPNFR----------------------KIDPHIP----HTEGVDTLALF 3780
            |.|....|:||..: ||...|                      .|.|..|    |:. ...|:|.
Human  3452 GPFPPLRRQELLDE-WLALCRGFQEALGPDDVAQALKRKQKSVSIPPKNPLLATHSP-FSILSLL 3514

  Fly  3781 SDDAQIAAWNNEGLPMDRMSTENATILQ----YST-RWPLMIDPQLQGIKWI------KNR-FGT 3833
            |.:::...|:....|..:.:.....:|:    ||: ||||::||..:.:.|:      :|| |..
Human  3515 SSESEQYQWDGNLKPQAKSAHLAGLLLRSPTHYSSCRWPLLLDPSNEALIWLDPLPLEENRSFAP 3579

  Fly  3834 DLVVLRLRQKGFL-------------------------------------------------EAL 3849
            .|.  ..|.||.:                                                 :..
Human  3580 ALT--EGRGKGLMRNQKRESKTDMKEEDDESEESNEAEDQTKEQKAEERKNEQEKEQEENEEKEE 3642

  Fly  3850 EKSISQG---------------------DTVLIEQIEESMDTVLEPLLSRALIKKGRYLRIGDKE 3893
            ||:.|||                     |..|..|::|:....|..||:..      .|.:|.:|
Human  3643 EKTESQGSKPAYETQLPSLPYLSVLSGADPELGSQLQEAAACGLPVLLTNV------ELGLGCEE 3701

  Fly  3894 IEFHASFRLILHTKMANPHYKPE--MQAQTTL-------------------INFTVTPDGLEEQL 3937
            :::     |:...:::.|..:|.  :...|||                   ::..:..:.||||:
Human  3702 LQW-----LLQREQLSPPQVQPGFCLYLSTTLSLCAMEKVLGCELLKGLNVLDLGLNMEILEEQM 3761

  Fly  3938 LAEVVKIERPDLEQMKTEVTVQQNKFKISLKALEDELLARLASSGENVLDDHALVINLENTKRTV 4002
            |.|::..|.|:||....::.::......:::|.|:.||..|.............:.|:...:..:
Human  3762 LHEILCREYPELETRWQDLKIRALDTCKAVEAAEERLLTMLLFQNPKRQKPAKFLRNIVRAQGKL 3826

  Fly  4003 DEIEAKVREARVTTLQIDDTRNIYRSAAKRAAILYFVLTDLSRINPIYKFSLKSFMNVFRQAI-A 4066
            .::.|...|.....||.......||........:...|:.|..:.|::..|.::::.|.:||: :
Human  3827 CQLRAHCEELEGQKLQEMVLWAPYRPVVWHGMAMVKALSQLQNLLPLFCMSPENWLAVTKQALDS 3891

  Fly  4067 MAAESKNY-EKRVLHLVE---SITLQTYRYTLRGLFEADKLTFTSHMTLRILIAAEQVAKDETDF 4127
            |.....|: |....||::   .:|.|....|:..|.........:...|.:|.|..:.:  |.:.
Human  3892 MKPREINHGEDLASHLLQLRAHLTRQLLGSTVTALGLTQVPLVGALGALALLQATGKAS--ELER 3954

  Fly  4128 LLRFP---HDPTTL--SPLDFVGRSAWGGIKS------LTLIEHFYGIDKDMENYTKRWRKFMAS 4181
            |..:|   ..|:|:  .|:..|.|.||.|.|:      |.|:..|.|:...:..::..|:.:::.
Human  3955 LALWPGLAASPSTVHSKPVSDVARPAWLGPKAWHECEMLELLPPFVGLCASLAGHSSAWQAYLSL 4019

  Fly  4182 DTPEREQFPGEW-KHRTPLQKLCIIRSLRPDRMTYAMRQFVEQTMGR-----SYAEIQTPPFGAI 4240
            .:......||.. :..:.||||.:.|.|||:.:..|:..|....:||     :||  .|.|
Human  4020 SSTVLGPAPGPGPEPLSLLQKLILWRVLRPECLAGALADFTTSLLGRPLDENTYA--PTMP---- 4078

  Fly  4241 FQELNAATPAFFILSP------GVDPIRDVER------YGQRQGFHSESDTLVNISLGQGQELLA 4293
            |:...|..|...:|.|      .:.|:..:::      .||:|        |..|:|| .:....
Human  4079 FKHSQATQPMLILLPPPGHPSATLHPLTVIQKLAAKYQQGQKQ--------LQVIALG-SEAWDP 4134

  Fly  4294 EQAIIGALESGQ---QWVILQNIHLVVNWLPTLEKLI---------------ERIVLQSESKGES 4340
            ...::..|....   .|::|.|.||:.:|...|.:|:               |:::.|.||:..|
Human  4135 VSVVVSTLSQAMYEGHWLVLDNCHLMPHWPKELLQLLLELLGRAKVVADLESEQLLDQPESRNVS 4199

  Fly  4341 ----NFRLF--ISAEPAPDPQYHVIPQGILESSLKVVNEPPSGMAANLHKAWDNFSQ------DA 4393
                :|||:  :.||.:..     :|..:.:.|:.|.              |:...:      |:
Human  4200 TVHRDFRLWLIVPAESSAS-----LPAVLTQHSMPVF--------------WNQSLELGHVLIDS 4245

  Fly  4394 LETCTQEAEFKSILF--------ALCYFHAVAGERRKFGPQ------GWNKVYPFNIGDLTISSN 4444
            :|...|      :|:        .|...|.:...|:.:|.:      .|::|
Human  4246 VELAQQ------VLYMQPPTQALPLLLLHGLLLHRQLYGTRLQAHRGRWSQV------------- 4291

  Fly  4445 VLHNYLEGSNRIPWEDL-------RYLFGEIMYGGHITDDWDRR----LCQ--------TYLEEL 4490
            .|...|:..::: |..|       :.|...:.|||.:.|..||.    |.|        ::::..
Human  4292 TLTQVLQTQDQL-WASLSNPRAAMQELAASVFYGGPLGDTEDREALISLTQACLSPSSGSWVQPH 4355

  Fly  4491 LQQDLIDGDFELCPGFPAPPNLDFEGYHSYITEMLPE-ESPLLYGLHPNAEIGFLTTASEQLLRT 4554
            ..|.|:   ..|.| .|....||..........:||. ..|.|.||....:...|...|..||..
Human  4356 TPQSLL---ATLMP-LPELRELDAMAECKAQMHLLPSPPEPRLCGLSEGPQAWLLRRQSRALLSA 4416

  Fly  4555 IFELQP---RESELSSHCGAPREELVKIMIDDFLDKLQDEFNLQALLNRVER------------- 4603
            :....|   .||...:.....|.....:.::..|:.|||      ||..|.|
Human  4417 LQRSSPVWVPESRRGAQLAERRLRQRLVQVNRRLESLQD------LLTHVIRQDESDAPWSVLGP 4475

  Fly  4604 --KTPFVVVALQECERMNALIREIKRSLRELMLGLRGELTI-TQEMERLDHAIFYDHVPAAWARL 4665
              :.|...|...|...::.|:..::|.|..|:..|:|.... ::....:.||::...:|..|...
Human  4476 NARRPLEGVLETEALELSQLVGTLQRDLDCLLQQLKGAPPCPSRRCAAVAHALWTGRLPLPWRPH 4540

  Fly  4666 AYPSMLGLQSWFADLLHRIKELAGWLN-----DFKLPCAIW-LGGLFNPQSFLTAIMQESARKHD 4724
            |.........|...|..|.:.|..:|.     ...:|..:: |....:|:..|.|:..|:|...:
Human  4541 APAGPQPPWHWLRQLSRRGQLLVRYLGVGADASSDVPERVFHLSAFRHPRRLLLALRGEAALDQN 4605

  Fly  4725 LPL-----DRMLISCDVTKKQKDDVTLP-------------PMEGAFVHDLYMDGASWDCQLNSI 4771
            :|.     .|..:|..:..|:.:..:.|             |..|..:..|.:..|.|| .:...
Human  4606 VPSSNFPGSRGSVSSQLQYKRLEMNSNPLHFRVENGPNPTVPERGLLLIGLQVLHAEWD-PIAGA 4669

  Fly  4772 VALRPKEMLCAMPVIYIKSIVQEKQELQ-----RVYECPLY--------KTRSRGNTYVWTFNLK 4823
            :...|......:|.:.|.:......:|.     .||.||:|        |.:||  ..|....|.
Human  4670 LQDSPSSQPSPLPPVSISTQAPGTSDLPAPADLTVYSCPVYMGGPLGTAKLQSR--NIVMHLPLP 4732

  Fly  4824 TRERPS 4829
            |:..|:
Human  4733 TKLTPN 4738

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG3339	NP_001036762.2	DHC_N1	276..903	CDD:285571	90/442 (20%)
		DHC_N2	1535..1944	CDD:285579	103/507 (20%)
		P-loop_NTPase	2095..2324	CDD:304359	66/258 (26%)
		P-loop_NTPase	2409..2544	CDD:304359	42/156 (27%)
		P-loop_NTPase	2731..3061	CDD:304359	77/366 (21%)
		P-loop_NTPase	3138..3406	CDD:304359	67/303 (22%)
		MT	3419..3759	CDD:289543	79/359 (22%)
		AAA_9	3789..4001	CDD:289547	56/314 (18%)
		Dynein_heavy	4142..4832	CDD:281078	170/832 (20%)
DNHD1	NP_653267.2	DHC_N2	1019..1467	CDD:285579	101/484 (21%)
		P-loop_NTPase	1649..1867	CDD:304359	60/222 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	2688..2766		2/77 (3%)
		P-loop_NTPase	2870..3119	CDD:304359	66/279 (24%)
		MT	<3193..3467	CDD:289543	70/297 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	3580..3657		9/78 (12%)
		AAA_9	<3664..3802	CDD:289547	30/148 (20%)
		Dynein_heavy	3979..4741	CDD:281078	168/827 (20%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	4669..4697		3/27 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5245
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.900