DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hmu and SS2

DIOPT Version :9

Sequence 1:	NP_477159.1	Gene:	Hmu / 43294	FlyBaseID:	FBgn0015737	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_177542.1	Gene:	SS2 / 843740	AraportID:	AT1G74020	Length:	335	Species:	Arabidopsis thaliana

Alignment Length:	366	Identity:	94/366 - (25%)
Similarity:	156/366 - (42%)	Gaps:	90/366 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    69 GPECLI--ARNNEIYTGIHGGEVIK-LTSNHVTHVTKIGQPCEDIYEE--------SRCGRPLGL 122
            |||...  :.....|||:.||:::| |.........:|.:.....:.:        .|||||.|:
plant    38 GPEAFAFDSTGKGFYTGVSGGKILKYLPETGYVDFAQITESSNSSWCDGTIGTALAGRCGRPAGI 102

  Fly   123 AFDTQGNNLIIADAYYGLWQVDLGTNKKTLLVSPAQELAGK---SIN-RPAKIFNGVTVS-KEGD 182
            ||:.:..:|.:|||..||.           ::|||..||.|   |:: :|.|..:|:.|. ..|.
plant   103 AFNEKTGDLYVADAPLGLH-----------VISPAGGLATKITDSVDGKPFKFLDGLDVDPTTGV 156

  Fly   183 VYWTDSSSDFT-IEDLVFASFANPSGRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAET 246
            ||:|..||.|: |:.|:.....:.:|:|:||:.|..|..||::.|:.:.|.|:|.:..|::|::.
plant   157 VYFTSFSSRFSPIQVLIALGLKDATGKLYKYDPSTKVVTVLMEGLSGSAGCAVSSDGSFVLVSQF 221

  Fly   247 GAMRLTKYHLKGAKAGQSEVFVDGLPGLPDNL--TPDAEGIWVPLVQSADSEHPNGFTLFTRFPS 309
            ....:.:|.:||.|||.||.|.:.:.. |||:  .......||..|
plant   222 TKSNIKRYWIKGPKAGSSEDFTNSVSN-PDNIKRIGSTGNFWVASV------------------- 266

  Fly   310 VRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVGSLH 374
                                   .||                ::.|...:.|:|:.||.::.::.
plant   267 -----------------------VNK----------------IIVPTNPSAVKVNSNGEVLQTIP 292

  Fly   375 GFDKSAAT-VSHVLEFQDFLFLGSPTNQYLARVKSPKAKQP 414
            ..||...| :|.|.||:..|::|:.|..:...:|..|...|
plant   293 LKDKFGDTLLSEVNEFEGNLYIGTLTGPFAGILKLEKGSCP 333

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmu	NP_477159.1	YvrE	61..>287	CDD:225921	71/236 (30%)
Hmu	NP_477159.1	Str_synth	173..258	CDD:304606	26/86 (30%)
SS2	NP_177542.1	YvrE	44..293	CDD:225921	78/318 (25%)
SS2	NP_177542.1	Str_synth	146..234	CDD:281131	27/87 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	48	1.000	Domainoid score	I4480
eggNOG	1	0.900	-	-		E1_COG1185
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757814at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3471
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10426
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X608
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.880