DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hmu and SS3

DIOPT Version :9

Sequence 1:	NP_477159.1	Gene:	Hmu / 43294	FlyBaseID:	FBgn0015737	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_177540.3	Gene:	SS3 / 843738	AraportID:	AT1G74000	Length:	329	Species:	Arabidopsis thaliana

Alignment Length:	352	Identity:	90/352 - (25%)
Similarity:	145/352 - (41%)	Gaps:	88/352 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 GRVYGPECLI--ARNNEIYTGIHGGEVIKLTSN-------HVTHVTKIGQPCEDIY---EESRCG 117
            |...|||...  :.....|||:.||:::|....       .:|:.:| ...|:...   ...:||
plant    36 GNRTGPEAFAFDSTGKGFYTGVTGGKILKYLPKKGYVDFAQITNSSK-SSLCDGALGTTNVEKCG 99

  Fly   118 RPLGLAFDTQGNNLIIADAYYGLWQVDL--GTNKKTLLVSPAQELAGKSINRPAKIFNGVTVS-K 179
            ||.|:||:|:..:|.:|||..||..:..  |..||.     |..:.||    |....:|:.|. .
plant   100 RPAGIAFNTKTGDLYVADAALGLHVIPRRGGLAKKI-----ADSVGGK----PFLFLDGLDVDPT 155

  Fly   180 EGDVYWTDSSSDFTIEDLVFA-SFANPSGRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVV 243
            .|.||:|..||.|...|::.| :..:.:|:.|||:.||.|..||::.|:.:.|.|:|.:..|::|
plant   156 TGVVYFTSFSSTFGPRDVLKAVATKDSTGKFFKYDPSKKVVTVLMEGLSGSAGCAVSSDGSFVLV 220

  Fly   244 AETGAMRLTKYHLKGAKAGQSEVFVDGLPGLPDNL--TPDAEGIWVPLVQSADSEHPNGFTLFTR 306
            .:.....:.:|.:||:|||.||.|.:.:.. |||:  .......||..|
plant   221 GQFTKSNIKRYWIKGSKAGTSEDFTNSVSN-PDNIKRIGSTGNFWVASV---------------- 268

  Fly   307 FPSVRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVG 371
                                 :||                     ...|...:.|:|...|.::.
plant   269 ---------------------VNS---------------------ATGPTNPSAVKVSSAGKVLQ 291

  Fly   372 SLHGFDKSAAT-VSHVLEFQDFLFLGS 397
            ::...||...| ||.|.|::..|::|:
plant   292 TIPLKDKFGDTLVSEVNEYKGQLYIGA 318

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmu	NP_477159.1	YvrE	61..>287	CDD:225921	72/239 (30%)
Hmu	NP_477159.1	Str_synth	173..258	CDD:304606	27/86 (31%)
SS3	NP_177540.3	YvrE	46..295	CDD:225921	77/317 (24%)
SS3	NP_177540.3	Str_synth	148..236	CDD:354965	28/87 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	48	1.000	Domainoid score	I4480
eggNOG	1	0.900	-	-		E1_COG1185
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1870
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757814at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm3471
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR10426
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X608
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	10	9.930