DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hmu and LAP3

DIOPT Version :9

Sequence 1:	NP_477159.1	Gene:	Hmu / 43294	FlyBaseID:	FBgn0015737	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001325620.1	Gene:	LAP3 / 825122	AraportID:	AT3G59530	Length:	403	Species:	Arabidopsis thaliana

Alignment Length:	408	Identity:	107/408 - (26%)
Similarity:	174/408 - (42%)	Gaps:	95/408 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 PFKDYIVTPPKDLKGALESNFHLEGAERLLEGRVYGPECL----IARNNEIYTGIHGGEVIKLTS 94
            |:|:.:.:.|:|....|.::..||..:     :|:|||.|    :.|..  |||:..|.|::...
plant    54 PYKEVMGSWPRDNLSRLGNHGKLEFVD-----QVFGPESLEFDSLGRGP--YTGLADGRVVRWMG 111

  Fly    95 NHV-----THVTK--IGQPC---------EDIYEESRCGRPLGLAFDTQGNNLIIADAYYGLWQV 143
            ..:     :.||.  ..:.|         :....|..|||||||.|..:..||.||||||||
plant   112 EAIGWETFSVVTSKWSEEACVRGVDSTTNKQWKHEKLCGRPLGLRFHKETGNLYIADAYYGL--- 173

  Fly   144 DLGTNKKTLLVSP----AQELAGKSINRPAKIFNGVTVSKEGDVYWTDSSSDFTIEDLVFASFAN 204
                    |:|.|    |..||.....:|....|.:.:.:.|.:::||:|..:...:..|.....
plant   174 --------LVVGPEGGIATPLATHVEGKPILFANDLDIHRNGSIFFTDTSKRYDRANHFFILLEG 230

  Fly   205 PS-GRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAETGAMRLTKYHLKGAKAGQSEVFV 268
            .| |||.:|:.....:.::|:.|||.||:.||.::.|::..||...||.||.|:|.|.|:.||..
plant   231 ESTGRLLRYDPPTKTTHIVLEGLAFPNGIQLSKDQSFLLFTETTNCRLVKYWLEGPKMGEVEVVA 295

  Fly   269 DGLPGLPDNLTPDAEG-IWVPL------VQSADSEHPNGFTLFTRFPSVRLFLARMLALFELPFR 326
            | |||.|||:..:.|| .||.:      .|...:.:|...:::.|.|.....||:.:.:
plant   296 D-LPGFPDNVRINEEGQFWVAIDCCRTPAQEVLTNNPWIRSIYFRLPIPMKLLAKTMGM------ 353

  Fly   327 YLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVGSLHGFDKSAATVSHVLEFQD 391
               .:|                         |.:.|.|..|.::..|.  |:....:.
plant   354 ---RMY-------------------------TVISRFDEEGKVLEVLE--DRQGKVMK------- 381

  Fly   392 FLFLGSPTNQYLARVKSP 409
             |::|:..:.::|.:..|
plant   382 -LWIGTVAHNHIATLPYP 398

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmu	NP_477159.1	YvrE	61..>287	CDD:225921	81/251 (32%)
Hmu	NP_477159.1	Str_synth	173..258	CDD:304606	27/85 (32%)
LAP3	NP_001325620.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	63	1.000	Domainoid score	I3710
eggNOG	1	0.900	-	-		E1_COG1185
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1870
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757814at2759
OrthoFinder	1	1.000	-	-		FOG0001350
OrthoInspector	1	1.000	-	-		otm3471
orthoMCL	1	0.900	-	-		OOG6_101875
Panther	1	1.100	-	-	O	PTHR10426
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X608
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.830