DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hmu and SSL4

DIOPT Version :9

Sequence 1:	NP_477159.1	Gene:	Hmu / 43294	FlyBaseID:	FBgn0015737	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_190710.1	Gene:	SSL4 / 824305	AraportID:	AT3G51420	Length:	370	Species:	Arabidopsis thaliana

Alignment Length:	422	Identity:	117/422 - (27%)
Similarity:	194/422 - (45%)	Gaps:	78/422 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 RIMNFMIFFLLIILM---------PGLPPRTTFPFKDYIVTPPKDLKGALESNFHLEGAERLLEG 65
            |.:.|.|||..:|.:         |...|      .|.::|.|..:...|...| |.|||.:..|
plant     8 RFLFFSIFFPCLISITLYQLDSFEPASLP------ADSLITSPTSIPPLLNDRF-LTGAEFIGVG 65

  Fly    66 RVYGPECLIAR--NNEIYTGIHGGEVIKLTSNHVTHVTKIGQPCEDIYEE--SRCGRPLGLAFDT 126
            .:..||.:...  :|.||||...|.|.:::.:...:        :.|.|:  :..|||||:||..
plant    66 LLNNPEDIAYHKDSNLIYTGCVDGWVKRVSVHDSAN--------DSIVEDWVNTGGRPLGIAFGL 122

  Fly   127 QGNNLIIADAYYGLWQVDLGTNKKTLLVSPAQELAGKSINRPAKIFNGVTVSKEGDVYWTDSSSD 191
            .| .:|:|||..||..:..|..|..||...|..:.       .|:.:.|||:..|.:|:||:||.
plant   123 HG-EVIVADANKGLLSISDGGKKTELLTDEADGVR-------FKLTDAVTVADNGVLYFTDASSK 179

  Fly   192 FTIEDLVFASF-ANPSGRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAETGAMRLTKYH 255
            :.....:|... ..|.||:..::.:...:.|||.:|.||||:::||::...|..||...|.:||:
plant   180 YDFYQFIFDFLEGKPHGRVMSFDPTTRATRVLLKDLYFANGISMSPDQTHFVFCETIMRRCSKYY 244

  Fly   256 LKGAKAGQSEVFVDGLPGLPDNLTPDAEG-IWVPLVQSADSEHPNGFTLFTRFPSVRLFLARMLA 319
            :...:.   |||:.||||.|||:..|.:| .|:.|:    ||....:.|..::    |||.:::
plant   245 ISEERV---EVFIQGLPGYPDNIRYDGDGHYWIALI----SEVTTSWKLSMKY----LFLRKLI- 297

  Fly   320 LFELPFRYLNSVYPNKFSQRFVHFVGHMESITVLAPKRTTVVRVDWNGNIVGSLHGFDKSAATVS 384
                   |:.:.|                .:.:|:.|...|::||.:||.:...|  |...:.::
plant   298 -------YMAAKY----------------GVELLSIKNAAVLQVDLDGNPIAMYH--DHPFSHIT 337

  Fly   385 HVLEFQDFLFLGSPTNQYLAR---VKSPKAKQ 413
            ..::..:.|:.||..:.|:.|   :|.|..|:
plant   338 SGVKIGNHLYFGSLLHSYITRLDLLKYPAQKK 369

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmu	NP_477159.1	YvrE	61..>287	CDD:225921	73/231 (32%)
Hmu	NP_477159.1	Str_synth	173..258	CDD:304606	29/85 (34%)
SSL4	NP_190710.1	YvrE	70..>278	CDD:225921	74/230 (32%)
SSL4	NP_190710.1	Str_synth	161..248	CDD:281131	29/86 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	63	1.000	Domainoid score	I3710
eggNOG	1	0.900	-	-		E1_COG1185
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	131	1.000	Inparanoid score	I1870
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D757814at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101875
Panther	1	1.100	-	-	O	PTHR10426
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	9	8.830