DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Hmu and Pnpt1

DIOPT Version :9

Sequence 1:	NP_477159.1	Gene:	Hmu / 43294	FlyBaseID:	FBgn0015737	Length:	579	Species:	Drosophila melanogaster
Sequence 2:	NP_001135843.1	Gene:	Pnpt1 / 360992	RGDID:	1307987	Length:	784	Species:	Rattus norvegicus

Alignment Length:	308	Identity:	62/308 - (20%)
Similarity:	106/308 - (34%)	Gaps:	92/308 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly   185 WTDSSSDFTIEDLVFASFANPSGRLFKYNRSKNVSEVLLDELAFANGLALSPNEDFIVVAETGAM 249
            |:.:.|.....||........||:|.:                ||:|.|:..:.|..|:..  |:
  Rat    39 WSGTRSRAVTVDLGHRKLEISSGKLAR----------------FADGCAVVQSGDTAVMVT--AV 85

  Fly   250 RLTK------------YHLKGAKAGQSEVFVDGLPGLPDNLTPDAEGIWVPLVQSADSEHPNGFT 302
            ..||            |..|.|.||:          :|.|......|       |:|.|
  Rat    86 SKTKPSPSQFMPLVVDYRQKAAAAGR----------IPTNYLRREIG-------SSDKE------ 127

  Fly   303 LFTRFPSVRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESITVL-APKRTTVVRVDWN 366
            :.|.    |:....:..||...:.|...|..|..:   |..:...:.:.:. |....::..:.||
  Rat   128 ILTS----RVIDRSIRPLFPAGYFYDTQVLCNLLA---VDGINEPDILAINGASAALSLSDIPWN 185

  Fly   367 GNI----VGSLHG--------FDKSAATVSHVLEFQDFLFLGSPTNQYLARVKSPK--------- 410
            |.:    :|.:.|        .:.|::|::.|:       .|:|.:|.:....|.:
  Rat   186 GPVGAVRIGMIDGECVVNPTRKEMSSSTLNLVV-------AGAPKSQIVMLEASAENILQQDFCH 243

  Fly   411 AKQPTLKVRNVRVEG-EGLEASIGVPPSKATPKPKAAPSTTTPKPTTT 457
            |.:..:|.....::. :.|...|||  :|.||:....||....|.|.|
  Rat   244 AIKVGVKYTQQIIQSIQQLVKEIGV--AKRTPQKIFTPSAEIVKYTHT 289

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Hmu	NP_477159.1	YvrE	61..>287	CDD:225921	24/113 (21%)
Hmu	NP_477159.1	Str_synth	173..258	CDD:304606	17/84 (20%)
Pnpt1	NP_001135843.1	PRK11824	47..752	CDD:236995	60/300 (20%)
		RNase_PH_PNPase_1	47..273	CDD:206768	53/282 (19%)
		PNPase	290..363	CDD:281688	62/308 (20%)
		RNase_PH_PNPase_2	366..596	CDD:206769
		KH-I	605..664	CDD:294072
		S1	679..750	CDD:197648
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1185
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900