DRSC/TRiP Functional Genomics Resources

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Protein Alignment Hmu and T12G3.4

DIOPT Version :10

Sequence 1:NP_477159.1 Gene:Hmu / 43294 FlyBaseID:FBgn0015737 Length:579 Species:Drosophila melanogaster
Sequence 2:NP_502282.1 Gene:T12G3.4 / 178141 WormBaseID:WBGene00011739 Length:447 Species:Caenorhabditis elegans


Alignment Length:447 Identity:124/447 - (27%)
Similarity:190/447 - (42%) Gaps:94/447 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     1 MGLLYALRV------RIMNFMIFFLLIILMPGLPPRTTFPFKDYIVTPPKDLKGALESNFHLEGA 59
            :|||.:|.:      ||:|..|            ....|...|.|     .|:|.|..|..|..|
 Worm    54 LGLLGSLIIAGLLTNRIINAPI------------KAVEFDLGDKI-----PLEGVLAVNKRLTDA 101

  Fly    60 ERLLEGRVYGPECLI--ARNNEIYTGIHGGEVIKLTSNH----VTHVTKIGQ---PCEDIYEE-S 114
            |.||..:|||||.|:  .:|:::|.|...|.:.::....    :.|..::.|   .|:..|:: :
 Worm   102 ELLLVDQVYGPESLVLDEKNSKLYAGFKTGIIAEIDMKEGREKIVHAVQLAQGNHDCDGSYKKMN 166

  Fly   115 RCGRPLGLAFDTQGNNLIIADAYYGL----WQVDLGTNKKTLLVSPAQELAGKSIN-RPAKIFNG 174
            .|||||||.....| .|:|||||.||    ||     .:|.:.:..|.||...:.| .|.|..|.
 Worm   167 LCGRPLGLRLSDVG-ELVIADAYLGLFAINWQ-----EEKVVKILGAGELPANNENAAPIKYLND 225

  Fly   175 VTVSKEGDVYWTDSSSDFTIEDLVFASFAN-PSGRLFKYNRSKNVSEVLLDELAFANGLALSPNE 238
            :.:..:|.|.:|:||:.|...|.:...|.: |:|||..|:..|....||.|.|.|.||:.||..:
 Worm   226 LDILPDGRVIFTESSTKFDDRDFILDLFEHRPNGRLLIYDPRKKDLRVLKDGLYFPNGVQLSIEK 290

  Fly   239 DF-------IVVAETGAMRLTKY-----HLKGAKAGQSEVFVDGLPGLPDNLTPDAEG-IWVPLV 290
            ..       ::.:|.|..|:.:.     |...|....|.: ::.|||.|||:.....| :.:|:.
 Worm   291 GMGKNAPWRVLYSEMGLARVMQIWVPRDHYSTAPVKTSPL-IENLPGYPDNIRLTKSGHLLIPIA 354

  Fly   291 QSADSEHPNGFTLFTRF----PSVRLFLARMLALFELPFRYLNSVYPNKFSQRFVHFVGHMESIT 351
            .....|        .||    ||||.|:.::|:...|.:              ..::|..:|.:.
 Worm   355 SHRSEE--------DRFLEQNPSVREFITKILSPQALGY--------------VANYVADVEGLV 397

  Fly   352 VLAPKRTTVVRVDWNGNIVGSLHGFDKSAATVSHVL-EFQDFLFLGSPTNQYLARVK 407
            :.....|        |.|:.|.|........||..: :.:..:.|||..|.|:||.|
 Worm   398 IKVNTET--------GQIIESYHDQTGRVEAVSIAIDDGKGRMLLGSDVNYYIARAK 446

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
HmuNP_477159.1 YvrE 61..>287 CDD:442613 78/254 (31%)
T12G3.4NP_502282.1 YvrE 112..>351 CDD:442613 73/245 (30%)
Str_synth 224..315 CDD:354965 27/90 (30%)

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