DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment bigmax and mlx

DIOPT Version :9

Sequence 1:	NP_651556.2	Gene:	bigmax / 43293	FlyBaseID:	FBgn0039509	Length:	254	Species:	Drosophila melanogaster
Sequence 2:	XP_017209811.1	Gene:	mlx / 554119	ZFINID:	ZDB-GENE-050522-316	Length:	253	Species:	Danio rerio

Alignment Length:	257	Identity:	103/257 - (40%)
Similarity:	153/257 - (59%)	Gaps:	34/257 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     1 MSDNNNALATKEDVF-----------GMEH----DQDHTSKHYSRCSSAGSTHTPNSSAHNSDDD 50
            |::|:   |:.||.:           |.:|    :........||.:|.|||..  ||..|:||:
Zfish     1 MTENS---ASPEDPWLKQTDGTFSDNGFDHSFFAESARKGSLVSRANSIGSTSA--SSVPNTDDE 60

  Fly    51 DDSGDARHSAAANSTLSYKERRREAHTQAEQKRR------DAIKKGYDSLQELVPRCQPNDS--- 106
            |  .|.||......  |||:|||.||||||||||      ||.:||||.||.:||.||....
Zfish    61 D--SDNRHETPYKE--SYKDRRRHAHTQAEQKRRDNQGMCDAFQKGYDDLQSIVPTCQQQSDFSM 121

  Fly   107 SGYKLSKALILQKSIEYIGYLNQQKLKQEDEGSALQKEVTALRIIKNGYENMLQHQQANPGPEEA 171
            :..|:|||.:|||:|:||.:|:::|.|||::.|.|:|||.||:|:|..||::::..|.||.....
Zfish   122 ATQKMSKATVLQKTIDYIQFLHKEKKKQEEDVSTLRKEVMALKIMKTNYEHIVKAHQNNPQQGSE 186

  Fly   172 RLTDEAKFQVFQAIMEEMFETFQ-HIPMENFKQLTTGIIPWLEEHCKPHILRNILSRTLQQM 232
            :::|:.||.|||:||:.:|::|. .:.:.:|::|:..:..|:||||||..||..:...|||:
Zfish   187 QVSDQVKFSVFQSIMDSLFQSFSASVSVSSFQELSACVFSWIEEHCKPQTLREFVVTVLQQV 248

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
bigmax	NP_651556.2	HLH	69..130	CDD:238036	37/69 (54%)
mlx	XP_017209811.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170574616
Domainoid	1	1.000	94	1.000	Domainoid score	I7482
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H7969
Inparanoid	1	1.050	141	1.000	Inparanoid score	I4461
OMA	1	1.010	-	-		QHG45474
OrthoDB	1	1.010	-	-		D1234389at2759
OrthoFinder	1	1.000	-	-		FOG0007499
OrthoInspector	1	1.000	-	-		oto41425
orthoMCL	1	0.900	-	-		OOG6_106895
Panther	1	1.100	-	-	LDO	PTHR15741
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X6384
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	13	12.910